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We are showing a significant enhancement in the temporal contrast by reducing the coherent noise of the 10 PW laser system at the Extreme Light Infrastructure - Nuclear Physics facility. The temporal contrast was improved by four orders of magnitude at 10 picoseconds and by more than one order of magnitude at 50 picoseconds before the main peak. This improvement of the picosecond contrast is critical for the experiments using thin solid targets.
Antenna arrays are a main driver of next generation millimeter-wave communication and radar systems as shrinking antenna sizes leverage larger arrays to compensate for reduced link budget. However, conventional phase controlled arrays exhibit a frequency dependent scan angle that appears as loss to a fixed counterpart. Bandwidth limitations introduced by the so-called beam squint effect hinder larger array sizes and data rates thereby generating a demand for timed arrays as a solution. This paper gives a quantified overview of the beam squint phenomenon, different hardware architectures as well as evaluation parameters and common shortcomings of true-time delay (TTD) elements. A broad variety of TTD realizations from literature are compared by their operational principles and performance. Finally, the delay interpolation principle, its non-idealities, and their impact on a hierarchically time delay controlled D-band antenna array are described. Extended content on a previously published, continuously tunable TTD implementation at a center frequency of 144 GHz with a bandwidth of 26 GHz and a delay range of 1.75 ps that requires only 0.53 × 0.3 mm2 of core chip area is presented. Measurement results have been obtained from a demonstrator manufactured in 130 nm BiCMOS technology.
The International Psychogeriatric Association (IPA) published a provisional consensus definition of agitation in cognitive disorders in 2015. As proposed by the original work group, we summarize the use and validation of criteria in order to remove “provisional” from the definition.
Methods:
This report summarizes information from the academic literature, research resources, clinical guidelines, expert surveys, and patient and family advocates on the experience of use of the IPA definition. The information was reviewed by a working group of topic experts to create a finalized definition.
Results:
We present a final definition which closely resembles the provisional definition with modifications to address special circumstances. We also summarize the development of tools for diagnosis and assessment of agitation and propose strategies for dissemination and integration into precision diagnosis and agitation interventions.
Conclusion:
The IPA definition of agitation captures a common and important entity that is recognized by many stakeholders. Dissemination of the definition will permit broader detection and can advance research and best practices for care of patients with agitation.
To develop an agitation reduction and prevention algorithm is intended to guide implementation of the definition of agitation developed by the International Psychogeriatric Association (IPA)
Design:
Review of literature on treatment guidelines and recommended algorithms; algorithm development through reiterative integration of research information and expert opinion
Setting:
IPA Agitation Workgroup
Participants:
IPA panel of international experts on agitation
Intervention:
Integration of available information into a comprehensive algorithm
Measurements:
None
Results
The IPA Agitation Work Group recommends the Investigate, Plan, and Act (IPA) approach to agitation reduction and prevention. A thorough investigation of the behavior is followed by planning and acting with an emphasis on shared decision-making; the success of the plan is evaluated and adjusted as needed. The process is repeated until agitation is reduced to an acceptable level and prevention of recurrence is optimized. Psychosocial interventions are part of every plan and are continued throughout the process. Pharmacologic interventions are organized into panels of choices for nocturnal/circadian agitation; mild-moderate agitation or agitation with prominent mood features; moderate-severe agitation; and severe agitation with threatened harm to the patient or others. Therapeutic alternatives are presented for each panel. The occurrence of agitation in a variety of venues—home, nursing home, emergency department, hospice—and adjustments to the therapeutic approach are presented.
Conclusions
The IPA definition of agitation is operationalized into an agitation management algorithm that emphasizes the integration of psychosocial and pharmacologic interventions, reiterative assessment of response to treatment, adjustment of therapeutic approaches to reflect the clinical situation, and shared decision-making.
Societal concern for animals under human care has influenced our approaches to advance animal welfare in a variety of contexts. The Animal Programs Department at the Columbus Zoo and Aquarium sought partnership with the Center for Human-Animal Interactions Research & Education (CHAIRE) at The Ohio State University to develop a holistic welfare approach for the animals within their department using a focal species, the cheetah (Acinonyx jubatus). A one-year project using the Five Domains Animal Welfare Model collected data over six 60-day periods to evaluate long-term cortisol production and behavioural observations of cheetahs under changing environmental factors. Species and individual histories were incorporated with behavioural observations and hair cortisol production, giving a holistic view of welfare. Cortisol and behavioural data were analysed using linear models to compare cheetahs at population and individual levels. Participation in a cheetah run activity, housing occupancy, and 60-day period were found to influence all behaviours within the population and stereotypic behaviour also differed within individual cheetahs. No differences in hair cortisol concentrations were found for the group, but further analysis revealed differences within individuals throughout the study. No correlation of stereotypic behaviour and cortisol levels were found. This study created a welfare assessment protocol that can be used within zoological institutes and was the first to measure cortisol concentrations in hair in cheetahs.
The election of Kamala Harris as the first South Asian American Vice President of the United States has expanded interest in the long history of connections between the United States and South Asia. Harris joins an impressive roster of Indian American politicians—a roster that spans the political spectrum from conservative Republican governors like Nikki Haley and Bobby Jindal to progressive Democratic members of congress like Ro Khanna and Pramila Jayapal. It would be a mistake to see the growing political prominence of the South Asian American community as a clear marker of the unity or visibility of that community. Indeed, questions of identity and authenticity mark many of the most prominent Indian American politicians—including Harris, Haley, and Jindal. What it means to be South Asian American—or Indian American—has long been bound up with complex and ever-shifting boundaries of race, nation, and religion. Those boundaries were in turn linked to larger and longer histories of mutual perception, multifaceted entanglements and concrete interactions between the United States and South Asia.
For decades, the historiography on modern South Asia has been tethered to the signposts of Empire and the nation-state as its recurrent referents. Even as postcolonial theory, Subaltern studies and feminist theory sought to expand the intellectual terrain, the dominance of the nation-Empire dyad has continued more or less unabated. The gradual waning of the Cold War, concurrent with the rise of Global History, has, however, brought into sharper focus the methodological limitations and shortcomings of both Imperial history and Area Studies. This edited volume offers a fresh approach to the intellectual, cultural, economic and literary histories that have “entangled” the United States of America and the Indian subcontinent. After global history had been initially dominated by transregional comparisons and the study of (unilateral) long-distance transfers, the more dynamic and process-oriented concept of “entanglement” became increasingly prominent in the field from the late 1990s onwards, producing myriad studies on the “back and forth of people ideas and things across boundaries”. The shift toward interactive “transnational” histories at times risked an uncritical celebration of connections and entanglements of various kinds, as if such histories could themselves usher in a new and more just way of looking at the human past. A “breathless sense of freedom,” to use the words of historian Paul Kramer, tinged even many of the richest transnational histories.
For parasites in natural systems, the most common pattern of spatial distribution is aggregation among hosts. The main causes of such aggregation are variable exposure of hosts to parasites and heterogeneity in host susceptibility. The objective of this study was to determine if there are differences in the aggregation pattern of two species of ectoparasitic flies between the Pantanal and Cerrado regions of Brazil on the bat Artibeus planirostris. We collected the ectoparasites from bats captured between 2002 and 2017 with mist nets in 21 sites in the Pantanal and 15 sites in the surrounding plateaus. The results showed that the aggregation of ectoparasitic flies in Pantanal was more pronounced than in Cerrado. The discrepancy aggregation index (D) of the bat fly Megistopoda aranea was 0.877 in Pantanal and 0.724 in Cerrado. The D values of Aspidoptera phyllostomatis was even higher, with 0.916 and 0.848 in the Pantanal and Cerrado, respectively. Differences in the shelters used may be the main factor shaping variation in aggregation, since the Pantanal does not have rock formations, with only foliage, crowns and hollow tree trunks. These differences likely affect host exposure to the parasites, leading to an increase in parasite aggregation.
In December 2010, a major storm erupted in Saturn’s northern hemisphere near 37° planetographic latitude. This rather surprising event, occurring at an unexpected latitude and time, is the sixth “Great White Spot” (GWS) storm observed over the last century and a half. Such GWS events are extraordinary, planetary-scale atmospheric phenomena that dramatically change the typically bland appearance of the planet. Occurring while the Cassini mission was on orbit at Saturn, the Great Storm of 2010–2011 was well suited for intense scrutiny by the suite of sophisticated instruments onboard the Cassini spacecraft as well by modern instrumentation on ground-based telescopes and onboard the Hubble Space Telescope. This GWS erupted on 5 December close to the peak of a westward jet and generated a major dynamical disturbance that affected the whole latitude band from 25° to 48°N. At the upper cloud level, following the rapid growth of the bright outbreak spot, a blunt aerodynamic-shaped head formed due to interaction of the spot with the westward zonal jet, with the winds reaching velocities of 160 m s−1 along the periphery of the arc. Eastward of the head, the disturbance progressed in the following months forming a turbulent wake or tail with growing vortices, one of them a major enduring anticyclone (called AV) with a size of ~11,000 km. Lightning events were prominent and detected as outbursts and flashes at the head and along the disturbance at both optical and radio wavelengths. The activity of the head ceased after about seven months when AV reached it, leaving the cloud structure and ambient winds perturbed. The tops of the optically dense clouds of the head reached the 300-mbar altitude level (~50 km below tropopause), where a mixture of ices was detected, including (1) a component of water ice lofted over 200 km altitude from its 10-bar condensation level, (2) ammonia ice as the predominant component and (3) a component that might be ammonium hydrogen sulfide ice. The energetics of the frequency and power of lightning, as well as the estimated power generated by the latent heat released in the water-based convection to create the observed dynamical three-dimensional flows, both indicate that the power released for much of the 7-month lifetime of the storm (~1017 Watts) was a significant fraction of Saturn’s total radiated power (~2.2 1017 W). A post-storm depletion of ammonia vapour was also measured in the upper troposphere. The effects of the storm propagated into the stratosphere, forming two warm air masses at the ~0.5- to 5-mbar pressure level altitude that later merged into a so-called “beacon” because of its 80 K temperature excess relative to its surroundings. Related to the stratospheric disturbance, hydrocarbon composition excesses were found, in particular for ethylene (C2H4), in the high stratosphere at the ~0.1- to 0.5-mbar altitude level. Numerical models of the storm dynamics explain the major observed features that essentially result from two processes: (1) a huge and sustained, moist, convective storm at the water clouds (altitude level 10–12 bar, or ~250–275 km below the tropopause) and (2) the interaction of the updraft columns with the ambient winds that generates the turbulent wake consisting of vortices and waves. Model simulations of the GWS require a low vertical shear of the zonal winds and low static stability across the weather layer where the disturbance develops. Its upward propagation into the stratosphere involves Rossby waves and their breaking and energy deposition to form the beacon and induce chemical changes.
The decades-long interval between storms is probably related to the insolation cycle and the long radiative time constant of Saturn’s atmosphere, and several theories for temporarily storing energy have been proposed.
We report a novel concept for the direct integration of capacitors in printed circuit boards using ultra-small BaTiO3 and ZrO2 nanoparticles prepared by a chemical method. Electrical properties comparable to surface mount ceramic capacitors were achieved by proper processing of the nanoparticles, achieving a device-yield of >90% under research environment. The loss factor of the presented integrated capacitors does not exceed 0.05 independent of frequency, capacitor’s electrode area or applied bias voltage.
American wartime policy regarding Russia continues to be disputed heatedly. In these controversies the genesis of Soviet-American relations in World War II, although it obviously played a key role in shaping both the victorious anti-Axis alliance and the uneasy peace that followed, has so far been neglected. To throw light on the initial rapprochement, this paper is presented as a survey of the half-year period in 1941 between the German attack on Russia and the Japanese attack on the United States.
Sumner Welles, Under Secretary of State in 1941, records that “the relations between the United States and the Soviet Union, particularly during the period of the German-Soviet agreement, had been practically non-existent.” The Soviet invasion of Finland, sharply resented by American public opinion, served to exacerbate relations further. Only after the German attack of June 22, 1941, did the two great powers draw together.
PLANET-B is an ISAS spacecraft which will investigate the upper atmosphere and the surroundings of Mars between 1999 and 2001 To clarify the presence and characteristics of the Martian dust ring/torus, an impact ionization dust detector will be on board PLANET-B The detector (PLANET B Mars Dust Counter), which is an improved version of the Munich Dust Counters of HITEN and BREMSAT, will weigh only 630g with an aperture area 140cm2. The detectable mass range will be between 10-16g and more than 10-6g and the velocity range will be from 1km/s to more than 70km/s. Since PLANET-B executes retrograde elliptic orbits close to the zodiacal plane, our detector can investigate the spatial distribution of prograde dust particles from Phobos and Deimos with relative encounter velocity as large as or higher than 1km/s. PLANET-B MDC shall also measure the dust environment around the Earth and interplanetary and possibly interstellar dust particles.
The double quasar 0957+561 was the first discovered instance of multiple imaging via gravitational lensing. The galaxy cluster is an important deflector as well as the first ranked galaxy. This has so far precluded construction of a unique model of the lens, reducing the accuracy of the derived H0 value. We have obtained deep images of the system at CFHT. The cluster is sufficiently massive to cause distortions on distant background galaxy images. We have used a mass map derived from lensing distortions to improve the accuracy of the cluster center location and place new limits on H0.