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Although active flow control based on deep reinforcement learning (DRL) has been demonstrated extensively in numerical environments, practical implementation of real-time DRL control in experiments remains challenging, largely because of the critical time requirement imposed on data acquisition and neural-network computation. In this study, a high-speed field-programmable gate array (FPGA) -based experimental DRL (FeDRL) control framework is developed, capable of achieving a control frequency of 1–10 kHz, two orders higher than that of the existing CPU-based framework (10 Hz). The feasibility of the FeDRL framework is tested in a rather challenging case of supersonic backward-facing step flow at Mach 2, with an array of plasma synthetic jets and a hot-wire acting as the actuator and sensor, respectively. The closed-loop control law is represented by a radial basis function network and optimised by a classical value-based algorithm (i.e. deep Q-network). Results show that, with only ten seconds of training, the agent is able to find a satisfying control law that increases the mixing in the shear layer by 21.2 %. Such a high training efficiency has never been reported in previous experiments (typical time cost: hours).
Although family factors are considered important for children’s language acquisition, the evidence comes primarily from affluent societies. Thus, this study aimed to examine the relations between family factors (family’s socioeconomic status [SES], home literacy activities, access to print resources, and parental beliefs) and children’s vocabulary knowledge in both urban and rural settings in China. Data from 366 children (urban group: 109, 4.85 years; rural group: 257, 4.89 years) were collected. Results showed that whereas family’s SES significantly predicted access to print resources and children’s vocabulary knowledge in the rural group, parental beliefs directly predicted children’s vocabulary knowledge in the urban group. Multigroup analysis showed that the associations of family’s SES and access to print resources with children’s vocabulary knowledge were stronger in the rural group than in the urban group. Our findings highlight the importance of considering contextual settings when conceptualising the role of family factors in children’s language acquisition.
Statisticians typically estimate the parameters of latent class and latent profile models using the Expectation-Maximization algorithm. This paper proposes an alternative two-stage approach to model fitting. The first stage uses the modified k-means and hierarchical clustering algorithms to identify the latent classes that best satisfy the conditional independence assumption underlying the latent variable model. The second stage then uses mixture modeling treating the class membership as known. The proposed approach is theoretically justifiable, directly checks the conditional independence assumption, and converges much faster than the full likelihood approach when analyzing high-dimensional data. This paper also develops a new classification rule based on latent variable models. The proposed classification procedure reduces the dimensionality of measured data and explicitly recognizes the heterogeneous nature of the complex disease, which makes it perfect for analyzing high-throughput genomic data. Simulation studies and real data analysis demonstrate the advantages of the proposed method.
Based on a contingent valuation method survey on air quality improvement in northern China, we construct several subjective perception determinants of respondents' valuation uncertainty from both the demand and perceived supply sides. Using the individual-level uncertainty measurements initially proposed by Wang and He (2011) and their alternative transformations, we analyze how these factors of demand and perceived supply sides affect people's valuation uncertainty. Our results demonstrate the significant contribution of these determinants in explaining respondents' uncertainty. On the demand side, people who ‘don't know much’ about benefits-related factors have the highest level of uncertainty, and those claiming to ‘know nothing’ most often report the lowest level of uncertainty. On the supply side, people who either do not trust or are not satisfied with the control policies tend to be more certain of their valuation. The subsequent analyses also suggest that these results be interpreted as negative certainty, which is attributed to a lack of interest.
As the southernmost part of the central segment of the Central Asian Orogenic Belt, the northern Alxa area is characterized by abundant Permian magmatism and records key information on the geological evolution of the Palaeo-Asian Ocean. This study reports new zircon U–Pb and Lu–Hf isotopic and whole-rock geochemical data of the early Permian (285–286 Ma) Huisentala gabbro and Huodonghaer diorites from the Zhusileng–Hangwula Belt in the northern Alxa area. The gabbro is characterized by high Al, Ca, Mg# and light rare-earth elements, and low K, P and high field strength elements (e.g., Ti, Nb and Ta). Furthermore, the gabbro shows heterogeneous zircon ϵHf(t) value (−2.5 to +2.6). The Huodonghaer diorites show high MgO (3.46–6.32 wt%), Mg# (49–58), Sr (408–617 ppm) and Ba (223–419 ppm), and low FeOT/MgO (1.27–1.83) and TiO2 (0.48–0.90 wt%), with geochemical features similar to the high-Mg andesite/diorite. They show radiogenic zircon ϵHf(t) values of +1.2 to +4.9 and high Th/Nb ratios. These features suggest that the Huisentala gabbro and the Huodonghaer diorites were derived from the partial melting of mantle peridotite that was metasomatized by subduction-related fluids and by subducted sediment-derived melts, respectively.
Shaded coffee systems can mitigate climate change by fixation of atmospheric carbon dioxide (CO2) in soil. Understanding soil organic carbon (SOC) storage and the factors influencing SOC in coffee plantations are necessary for the development of sound land management practices to prevent land degradation and minimize SOC losses. This study was conducted in the main coffee-growing regions of Yunnan; SOC concentrations and storage of shaded and unshaded coffee systems were assessed in the top 40 cm of soil. Relationships between SOC concentration and factors affecting SOC were analysed using multiple linear regression based on the forward and backward stepwise regression method. Factors analysed were soil bulk density (ρb), soil pH, total nitrogen of soil (N), mean annual temperature (MAT), mean annual moisture (MAM), mean annual precipitation (MAP) and elevations (E). Akaike's information criterion (AIC), coefficient of determination (R2), root mean square error (RMSE) and residual sum of squares (RSS) were used to describe the accuracy of multiple linear regression models. Results showed that mean SOC concentration and storage decreased significantly with depth under unshaded coffee systems. Mean SOC concentration and storage were higher in shaded than unshaded coffee systems at 20–40 cm depth. The correlations between SOC concentration and ρb, pH and N were significant. Evidence from the multiple linear regression model showed that soil bulk density (ρb), soil pH, total nitrogen of soil (N) and climatic variables had the greatest impact on soil carbon storage in the coffee system.
The risk of environmental contamination by severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in the intensive care unit (ICU) is unclear. We evaluated the extent of environmental contamination in the ICU and correlated this with patient and disease factors, including the impact of different ventilatory modalities.
Methods:
In this observational study, surface environmental samples collected from ICU patient rooms and common areas were tested for SARS-CoV-2 by polymerase chain reaction (PCR). Select samples from the common area were tested by cell culture. Clinical data were collected and correlated to the presence of environmental contamination. Results were compared to historical data from a previous study in general wards.
Results:
In total, 200 samples from 20 patient rooms and 75 samples from common areas and the staff pantry were tested. The results showed that 14 rooms had at least 1 site contaminated, with an overall contamination rate of 14% (28 of 200 samples). Environmental contamination was not associated with day of illness, ventilatory mode, aerosol-generating procedures, or viral load. The frequency of environmental contamination was lower in the ICU than in general ward rooms. Eight samples from the common area were positive, though all were negative on cell culture.
Conclusion:
Environmental contamination in the ICU was lower than in the general wards. The use of mechanical ventilation or high-flow nasal oxygen was not associated with greater surface contamination, supporting their use and safety from an infection control perspective. Transmission risk via environmental surfaces in the ICUs is likely to be low. Nonetheless, infection control practices should be strictly reinforced, and transmission risk via droplet or airborne spread remains.
In this paper, we survey some results on infinite planar graphs with nonnegative combinatorial curvature, related to the total curvature, the number of vertices with positive curvature and the automorphism group.
Image stitching is important for the perception and manipulation of undersea robots. In spite of a well-developed technique, it is still challenging for undersea images because of their inevitable appearance ambiguity caused by the limited light in the undersea environment, and local disturbance caused by moving objects, ocean current, etc. To get a clean and stable background panorama in the undersea environment, this paper proposes an undersea image-stitching method by introducing graph-based registration and blending procedures. Specifically, in the registration procedure, matching the features in each undersea image pair is formulated and solved by graph matching, to incorporate the structural information between features. In the blending procedure, an energy function on the indirect graph Markov random field is proposed, which takes both image consistency and neighboring consistency into consideration. Coincidentally, both graph matching and energy minimization can be mathematically formulated by integer quadratic programming problems with different constraints; the recently proposed graduated nonconvexity and concavity procedure is used to optimize both problems. Experiments on both synthetic images and real-world undersea images witness the effectiveness of the proposed method.
More mobile devices such as mobile phones and robots are wirelessly charged for convenience, simplicity, and safety, and it would be desirable to achieve three-dimensional (3D) wireless charging with high spatial freedom and long range. This paper proposes a 3D wireless charging cube with three orthogonal coils and supporting magnetic cores to enhance the magnetic flux outside the cube. The proposed system is simulated by Ansoft Maxwell and implemented by a downsized prototype. Both simulation and experimental results show that the magnetic cores can strengthen the magnitude of B-field outside the cube. The final prototype demonstrates that the power transfer distance outside the cube for getting the same induced electromotive force in the receiver coil is extended approximately by 50 mm using magnetic cores with a permeability of 2800. It is found that the magnitude of B-field outside the cube can be increased by increasing the width and the permeability of the magnetic cores. The measured results show that when the permeability of the magnetic cores is fixed, the induced electromotive force in the receiver coil at a point 300 mm away from the center of the cube is increased by about 2V when the width of the magnetic cores is increased from 50 to 100 mm. The increase in the induced electromotive force at an extended point implies a greater potential of wireless power transfer capability to the power pickup.
Previous neuroimaging studies demonstrated that retinal detachment (RD) subjects were associated with abnormal spontaneous brain activities; however, whether the altered interhemispheric functional connectivity (FC) occurred in RD patients remains unknown. The current study tried to explore the alternations of interhemispheric FC of the whole brain in unilateral RD patients using the voxel-mirrored homotopic connectivity (VMHC) method and their connections to clinical features. Methods: We recruited 30 patients with RD (16 males and 14 females) and 30 healthy controls (HCs) (16 males and 14 females) whose age and sex were closely matched. All subjects underwent the rs-fMRI scans. The VMHC method was applied to directly assess the hemispheres’ functional interaction. The VMHC in these brain areas, which could be used as biomarkers to differentiate RD from HC, was identified by the receiver operating characteristic (ROC) curve analyses. The relations between these patients’ clinical features and their mean VMHC signal values in multiple brain regions were calculated by Pearson correlation analysis. Results: RD patients had significantly lower VMHC values than HCs in the bilateral occipital lobe (Brodmann areas, BA 18), bilateral superior temporal gyrus (BA 39), and bilateral cuneus (BA 19). Moreover, the mean VMHC signal values of the bilateral cuneus were in positive correlation with the duration of the RD (r = 0.446, P = 0.013). Conclusion: Our results provided an evidence of disturbed interhemispheric FC in the visual area occurred in RD patients, which might provide some useful information to understand the neural mechanism of RD patients with acute vision loss. Furthermore, the VMHC values might indicate the progress of the RD.
A coaxial-output rolled strip pulse-forming line (RSPFL) with a dry structure is researched for the purpose of miniaturization and all-solid state of pulse-forming lines (PFL). The coaxial-output RSPFL consists of a coaxial-output electrode (COE) and a rolled strip line (RSL). The COE is characterized by quasi-coaxial structure, making the output pulse propagate along the axial direction with a small output inductance. The RSL is rolled on the COE, whose transmission characteristics are analyzed theoretically. It shows that the RSL can be regarded as a planar strip line when the rolling radius of the strip line is larger than 60 times of the thickness of the insulation dielectric layer of RSL. CST modeling was carried out to simulate the discharging characteristic of the coaxial-output RSPFL. It shows that the coaxial-output RSPFL can deliver a discharging pulse with a rise time <6 ns when the impedance of the RSL matches that of the COE, which confirms the theoretical analysis. A prototype of the coaxial-output RSPFL was developed. A 49-kV discharging pulse on a matched load was achieved when it was charged to 100 kV. The discharging waveform has a pulse width of 32 ns, with a rise time of 6 ns, which is consistent with the simulation waveform. An energy-storage density of 1.9 J/L was realized in the coaxial-output RSPFL. By the method of multi-stage connection in series, a much higher output voltage is convenient to be obtained.
Alligatorweed is well known for its potassium (K+)-accumulating
capabilities and its strong resistance to undesired growth conditions. The
results of this study revealed properties of K+ accumulation and
its contribution to drought stress in alligatorweed. In addition, we
attempted to characterize the molecular mechanisms of K+
accumulation in this plant. Alligatorweed plants showed a consistent
increase in biomass in response to external K+ concentrations,
ranging from micromolar levels up to 50 mmol L−1; K+
was also accumulated accordingly in the plants. The stem was the most
K+-accumulating organ, accumulating up to 13% of the
K+. Moreover, this K+ superaccumulation caused
improved resistance to drought stress. The apparent K+ uptake by
the roots showed a typical high-affinity property, and the Michaelis
constant increased at higher rates of plant K+ in the starting
materials. Furthermore, three putative, K+-uptake transporter
complementary DNAs (cDNAs) were isolated from alligatorweed (ApKUP1,
ApKUP2, and ApKUP3, respectively) using
degenerated primers and rapid amplification of cDNA end techniques. The
expression of ApKUP1 and ApKUP3 was
predominately localized to the leaves, whereas ApKUP2 was
expressed throughout the entire plant. The expression of
ApKUP1 and ApKUP3 was stimulated in the
stems and roots when K+ was depleted from the external medium.
Moreover, ApKUP3 expression was enhanced in the stem in
response to abscisic acid treatment and drought stress. In conclusion, our
findings provide further insight into the mechanisms of K+
accumulation linked to K+ uptake in alligatorweed.
Intra-uterine growth restriction (IUGR) impairs postnatal growth and skeletal muscle development in neonatal infants. This study evaluated whether dietary β-hydroxy-β-methylbutyrate Ca (HMB-Ca) supplementation during the early postnatal period could improve muscle growth in IUGR neonates using piglets as a model. A total of twelve pairs of IUGR and normal-birth-weight (NBW) male piglets with average initial weights (1·85 (sem 0·36) and 2·51 (sem 0·39) kg, respectively) were randomly allotted to groups that received milk-based diets (CON) or milk-based diets supplemented with 800 mg/kg HMB-Ca (HMB) during days 7–28 after birth. Blood and longissimus dorsi (LD) samples were collected and analysed for plasma amino acid content, fibre morphology and the expression of genes related to muscle development. The results indicate that, regardless of diet, IUGR piglets had a significantly decreased average daily weight gain (ADG) compared with that of NBW piglets (P<0·05). However, IUGR piglets fed HMB-Ca had a net weight and ADG similar to that of NBW piglets fed the CON diet. Irrespective of body weight (BW), HMB-Ca supplementation markedly increased the type II fibre cross-sectional area and the mRNA expression of mammalian target of rapamycin (mTOR), insulin-like growth factor-1 and myosin heavy-chain isoform IIb in the LD of piglets (P<0·05). Moreover, there was a significant interaction between the effects of BW and HMB on mTOR expression in the LD (P<0·05). In conclusion, HMB-Ca supplementation during the early postnatal period could improve skeletal muscle growth and maturity by accelerating fast-twitch glycolytic fibre development in piglets.
Conventional retrogression and re-aging (RRA) treatment could not be put to good use for combination property of Al–Zn–Mg–Cu alloys. The new RRA treatment fitted for spray formed Al–Zn–Mg–Cu alloy was investigated by transmission electron microscope, tensile, and conductivity tests. The results show that the pre-aging treatment with under aging of 120 °C for 16 h is beneficial for the redissolution of matrix precipitates during retrogression treatment. With the retrogression of 200 °C for 8 min, grain boundary precipitates are discrete and the corrosion resistance of the alloy is drastically increased. After re-aging (120 °C for 24 h) the strength of the alloy is increased again. According to the above-mentioned new RRA treatment, the ultimate tensile strength, yield strength, elongation, and conductivity of the alloy are 791 MPa, 736 MPa, 8.5%, and 39.5% IACS respectively, which is higher than that after conventional RRA treatment.
A congruent melting compound LiNaV2O6 has been synthesized by high-temperature solution reaction and it has been grown with sizes up to 11 × 6 × 2 mm3 by the top-seeded growth method for the first time. LiNaV2O6 crystallizes in the monoclinic system with space group C2/c, with a = 10.184(2) Å, b = 9.067(2) Å, c = 5.8324(11) Å, β = 108.965(14)°. UV–Vis–NIR diffuse reflectance spectrum of LiNaV2O6 shows that it has a wide transmittance range from 385 to 2500 nm. The ab initio calculations show that the birefringence of LiNaV2O6 is 0.136 at 589.3 nm. Therefore, LiNaV2O6 may be a new birefringent material. Based on the analysis of the relationship between crystal structure and linear optical properties, it is found that the large birefringence is attributed to the particular arrangement of V–O anionic groups.
Titanium oxide photoelectrodes have been used for water splitting for a few decades, but have low solar-to-hydrogen efficiencies. Perovskite halides (e.g., CH3NH3PbI3) have recently emerged as an efficient light absorber system. We try to combine the two materials to create new photoelectrodes to achieve a higher efficiency for hydrogen production. The photoelectrodes are investigated for water-splitting hydrogen production under Xe light irradiation by photoelectrochemical (PEC) reaction. Since perovskite halides are favorable light harvesters under UV and visible light irradiation, the composite films of titania and perovskite halide would achieve efficient water splitting. The hydrogen production rate using the composite films is higher than that using anatase TiO2 electrode. However, the composite films are not stable in water under light irradiation and the perovskite halide gradually decomposes into lead halide.