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Over the last 25 years, radiowave detection of neutrino-generated signals, using cold polar ice as the neutrino target, has emerged as perhaps the most promising technique for detection of extragalactic ultra-high energy neutrinos (corresponding to neutrino energies in excess of 0.01 Joules, or 1017 electron volts). During the summer of 2021 and in tandem with the initial deployment of the Radio Neutrino Observatory in Greenland (RNO-G), we conducted radioglaciological measurements at Summit Station, Greenland to refine our understanding of the ice target. We report the result of one such measurement, the radio-frequency electric field attenuation length $L_\alpha$. We find an approximately linear dependence of $L_\alpha$ on frequency with the best fit of the average field attenuation for the upper 1500 m of ice: $\langle L_\alpha \rangle = ( ( 1154 \pm 121) - ( 0.81 \pm 0.14) \, ( \nu /{\rm MHz}) ) \,{\rm m}$ for frequencies ν ∈ [145 − 350] MHz.
To test the presence of significant correlations between psychopathological symptoms in patients with dementia and the stress perceived by the primary caregiver.
Methods
Primary caregivers of patients with a DSM-IV diagnosis of dementia admitted to the neuro-psycho-geriatric-rehabilitation ward of the private hospital “Villa Maria Luigia”, Parma - Italy, between May and November 2008 were asked to take part in the study. The NPI scale (UCLA Neuropsychiatric Inventory - Commings J.L. et al., 1994) and a socio-demographic data collection schedule were administered to the primary caregiver willing to be involved in the study.
Results
Only 30 of the 40 eligible subjects agreed to take part to the study (75%). 35 significant correlations (according to Spearman's Correlation Index) were found. Those most highly significant (p< 0.001) were between stress perception and the following NPI symptom categories: delirium, hallucination, agitation, euphoria, apathy, disinhibition, aberrant physical activity and sleep disorders.
Conclusions
The psychopathological symptoms found to contribute mostly to distress of caregivers were those most showy and disruptive of behaviour; other symptoms, such as anxiety, depression, irritability and eating disorders are better tolerated as considered normal consequences of ageism. Interventions addressed to caregivers should provide them with detailed and structured coping instruments. Clear, therefore, the need for all health professionals, to structure an intervention aimed at caregivers characterized by two different phases:
1. To provide more tools to recognize those disorders which don’t emotionally involve them;
2. To give detailed, structured information useful to cope with these disorders in everyday life.
We report the successful use of the intubating laryngeal mask airway in a patient with maxillo-facial trauma for whom the facemask and laryngoscope were relatively contraindicated and the fibreoptic scope potentially difficult to use.
In order to explore the nature of glucose-6-phosphate dehydrogenase
(G6PD) deficiency in south-east Sicily, we have analysed the G6PD gene in
25 unrelated males with abnormal G6PD activity
and/or electrophoretic mobility, by using the analysis of the
appropriate PCR-amplified fragment
of DNA and subsequent digestion by appropriate restriction-enzymes, looking
for the presence of
certain known G6PD mutations. We amplified the entire G6PD coding
sequence into eight
fragments, followed by single-strand conformation polymorphism (SSCP)
analysis and sequencing of
those individual fragments that were found to be abnormal by SSCP.
Through these methods we
found a total of twelve G6PD Mediterranean variants with the
association of a silent mutation 1311
(also known as polymorphic site Bcl I), one G6PD Mediterranean without
this association, four G6PD A−
Val 68 and two G6PD Santamaria and five G6PD Chatham. In a subject with
normal activity
a mutation was found in exon 5, designated as G6PD Sao Borja. This is the
first report on the
molecular analysis of G6PD mutations in Sicily and we have obtained
evidence for four distinct classes of variants.
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