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We study the dynamics of thermal and momentum boundary regions in three-dimensional direct numerical simulations of Rayleigh–Bénard convection for the Rayleigh-number range $10^5\leq Ra \leq 10^{11}$ and $Pr=0.7$. Using a Cartesian slab with horizontal periodic boundary conditions and an aspect ratio of 4, we obtain statistical homogeneity in the horizontal $x$- and $y$-directions, thus approximating best an extended convection layer relevant for most geo- and astrophysical flow applications. We observe upon canonical use of combined long-time and area averages, with averaging periods of at least 100 free-fall times, that a global coherent mean flow is practically absent and that the magnitude of the velocity fluctuations is larger than the mean by up to 2 orders of magnitude. The velocity field close to the wall is a collection of differently oriented local shear-dominated flow patches interspersed by extensive shear-free incoherent regions which can be as large as the whole cross-section, unlike for a closed cylindrical convection cell of aspect ratio of the order 1. The incoherent regions occupy a 60 % area fraction for all Rayleigh numbers investigated here. Rather than resulting in a pronounced mean flow with small fluctuations about such a mean, as found in small-aspect-ratio convection, the velocity field is dominated by strong fluctuations of all three components around a non-existent or weak mean. We discuss the consequences of these observations for convection layers with larger aspect ratios, including boundary layer instabilities and the resulting turbulent heat transport.
To expedite the use of evidence-based smoking cessation interventions (EBSCIs) in primary care and to thereby increase the number of successful quit attempts, a referral aid was developed. This aid aims to optimize the referral to and use of EBSCIs in primary care and to increase adherence to Dutch guidelines for smoking cessation.
Methods:
Practice nurses (PNs) will be randomly allocated to an experimental condition or control condition, and will then recruit smoking patients who show a willingness to quit smoking within six months. PNs allocated to the experimental condition will provide smoking cessation guidance in accordance with the referral aid. Patients from both conditions will receive questionnaires at baseline and after six months. Cessation effectiveness will be tested via multilevel logistic regression analyses. Multiple imputations as well as intention to treat analysis will be performed. Intervention appreciation and level of informed decision-making will be compared using analysis of (co)variance. Predictors for appreciation and informed decision-making will be assessed using multiple linear regression analysis and/or structural equation modeling. Finally, a cost-effectiveness study will be conducted.
Discussion:
This paper describes the study design for the development and evaluation of an information and decision tool to support PNs in their guidance of smoking patients and their referral to EBSCIs. The study aims to provide insight into the (cost) effectiveness of an intervention aimed at expediting the use of EBSCIs in primary care.
Obsessive-compulsive (OC) symptoms may begin at any point of the life span. Comorbid psychiatric disorders in OCD is more a rule than an exception and can contribute to the OCD-related burden.
Objectives:
The goal of this study is to understand the trajectory of comorbid disorders in OCD according to the first manifested psychiatric disorder and their impact in the clinical manifestation of OCD and.
Methods:
1001 consecutive OCD outpatients from the Brazilian Obsessive-Compulsive Disorder Consortium were evaluated. Inclusion criterion: OCD as the main psychiatric diagnosis (DSM-IV). Exclusion criteria: comorbid schizophrenia and mental retardation. The instruments applied were: SCID-I; Y-BOCS; DY-BOCS, YGTSS (significant level =5%). To investigate the age at comorbidities onset Bayesian approach was performed. Those distributions contain all the information obtained by the data for the mean age at onset.
Results:
OCD patients that presented separation anxiety disorder (N=175, age of onset SAD 5.35) as first diagnosis had higher frequency of social phobia, simples phobia, generalized anxiety disorder and panic disorder (78.3%; p=0.05), somatoform disorders (13.1%; p=0.05) and post-traumatic stress disorder (30.3% p=0.003). OCD patients that presented ADHD (N=50, age of onset ADHD 6.42; age of onset OCD 13.08) as first diagnosis had higher frequency of substance abuse (16.0%; p=0.00001). OCD patients that presented tic disorders (N=44, age of onset tic disorder 6.86; age of onset OCD 16.18) as first diagnosis had higher frequency of OC spectrum disorders (50.0%; p=0.03).
Conclusion:
First psychopathological manifestation in OCD patients is associated with distinct long-term trajectory of comorbid psychiatric disorders.
The production of beef cattle has historically been an important component of the Southeast's agricultural economy. In 1977 the region had 24.6 million cattle and calves, accounting for more than 28 percent of the total mature beef animals in the United States [3]. Despite this large and active cattle industry, however, the region is substantially deficient in carcass beef production.
The B fields in OB stars (BOB) survey is an ESO large programme collecting spectropolarimetric observations for a large number of early-type stars in order to study the occurrence rate, properties, and ultimately the origin of magnetic fields in massive stars. As of July 2014, a total of 98 objects were observed over 20 nights with FORS2 and HARPSpol. Our preliminary results indicate that the fraction of magnetic OB stars with an organised, detectable field is low. This conclusion, now independently reached by two different surveys, has profound implications for any theoretical model attempting to explain the field formation in these objects. We discuss in this contribution some important issues addressed by our observations (e.g., the lower bound of the field strength) and the discovery of some remarkable objects.
It is now well established that a fraction of the massive (M > 8 M⊙) star population hosts strong, organised magnetic fields, most likely of fossil origin. The details of the generation and evolution of these fields are still poorly understood. The BinaMIcS project takes an important step towards the understanding of the interplay between binarity and magnetism during the stellar formation and evolution, and in particular the genesis of fossil fields, by studying the magnetic properties of close binary systems. The components of such systems are most likely formed together, at the same time and in the same environment, and can therefore help us to disentangle the role of initial conditions on the magnetic properties of the massive stars from other competing effects such as age or rotation. We present here the main scientific objectives of the BinaMIcS project, as well as preliminary results from the first year of observations from the associated ESPaDOnS and Narval spectropolarimetric surveys.
The Magnetism in Massive Stars (MiMeS) project represents the largest systematic survey of stellar magnetism ever undertaken. Based on a sample of over 550 Galactic B and O-type stars, the MiMeS project has derived the basic characteristics of magnetism in hot, massive stars. Herein we report preliminary results.
Titanium (IV) oxide, TiO2, has been the object of intense scrutiny for energy applications. TiO2 is inexpensive, non-toxic, and has excellent corrosion resistance when exposed to electrolytes. A major drawback preventing the widespread use TiO2 for photolysis is its relatively large band gap of ∼3eV. Only light with wavelengths shorter than 400 nm, which is in the ultraviolet portion of the spectrum, has sufficient energy to be absorbed. Less than 14 percent of the solar irradiation reaching the earth’s surface has energy exceeding this band gap. Adding dopants such as transition metals has long been used to reduce the gap and increase photocatalytic activity by accessing the visible part of the solar spectrum. The degree to which the band gap is reduced using transition metals depends in part on the overlap of the d-orbitals of the transition metals with the oxygen p-orbitals. Therefore, doping with anions such as nitrogen to modify the cation-anion orbital overlap is another approach to reduce the gap. Recent studies suggest that using a combination of transition metals and nitrogen as dopants is more effective at introducing intermediate states within the band gap, effectively narrowing it. Here we report the synthesis of mesoporous TiO2 spheres, co-doped with transition metals and nitrogen that exhibit a nearly flat absorbance response across the visible spectrum extending into the near infrared.
Buran-Kaya III is a rockshelter located in Crimea (Ukraine). It provides an exceptional stratigraphic sequence extending from the Middle Paleolithic to the Neolithic. Nine Paleolithic layers have been attributed to the Streletskaya or eastern Szeletian, Micoquian, Aurignacian, Gravettian, and Swiderian cultural traditions. Human remains from the richest Gravettian layer (6-1) are radiocarbon dated to 31.9 ka BP, and therefore represent, with Peştera cu Oase (Romania), one of the oldest anatomically modern humans in Europe. The aim of this study is to obtain a controlled stratigraphic sequence of Buran-Kaya III with new 14C dates from faunal and human bones, in their paleoenvironmental context. During our new excavations (2009–2011), sediments, bones, and teeth from the stratigraphical layers were sampled for sedimentological, geochemical, and 14C analyses. Fossil bones from the 2001 excavations were also analyzed. Accelerator mass spectrometry (AMS) 14C dating, including cross-dating, was performed at Groningen, Saclay/Gif-sur-Yvette, and Oxford. Biogeochemical analysis was used to test the integrity of the bone collagen. Dates were modeled using a Bayesian approach. The sedimentological, paleoenvironmental, and chronological data are mutually consistent and show that the Paleolithic human occupations at Buran-Kaya III range from the end of MIS 3 to early MIS 1. These results provide a new chronological and paleoenvironmental framework for the human settlements in eastern Europe during the late Middle and the Upper Paleolithic.
An energy resource is the first step in the chain that supplies energy services (for a definition of energy services, see Chapter 1). Energy services are largely ignorant of the particular resource that supplies them; however, often the infrastructures, technologies, and fuels along the delivery chain are highly dependent on a particular type of resource. The availability and costs of bringing energy resources to the market place are key determinants to affordable and accessible energy services.
Energy resources pose no inherent limitation to meeting the rapidly growing global energy demand as long as adequate upstream investment is forthcoming – for exhaustible resources in exploration, production technology, and capacity (mining and field development) and, by analogy, for renewables in conversion technologies.
Hydrocarbons and Nuclear
Occurrences of hydrocarbons and fissile materials in the Earth's crust are plentiful – yet they are finite. The extent of the ultimately recoverable oil, natural gas, coal, or uranium is the subject of numerous reviews, yet still the range of values in the literature is large (Table 7.1). For example, the range for conventional oil is between 4900 exajoules (EJ) for reserves to 13,700 EJ (reserves plus resources) – a range that sustains continued debate and controversy. The large range is the result of varying boundaries of what is included in the analysis of a finite stock of an exhaustible resource, e.g., conventional oil only or conventional oil plus unconventional occurrences, such as oil shale, tar sands, and extra-heavy oils.
Monitoring injecting drug users' (IDUs) health is challenging because IDUs form a difficult to reach population. We examined the impact of recruitment setting on hepatitis C prevalence. Individual datasets from 12 studies were merged. Predictors of HCV positivity were sought through a multilevel analysis using a mixed-effects logistic model, with study identifier as random intercept. HCV prevalence ranged from 21% to 86% across the studies. Overall, HCV prevalence was higher in IDUs recruited in drug treatment centres compared to those recruited in low-threshold settings (74% and 42%, respectively, P < 0·001). Recruitment setting remained significantly associated with HCV prevalence after adjustment for duration of injecting and recent injection (adjusted odds ratio 0·7, 95% confidence interval 0·6–0·8, P = 0·05). Recruitment setting may have an impact on HCV prevalence estimates of IDUs in Europe. Assessing the impact of mixed recruitment strategies, including respondent-driven sampling, on HCV prevalence estimates, would be valuable.
Schizophrenia patients demonstrate impairment on visual backward masking, a measure of early visual processing. Most visual masking paradigms involve two distinct processes, an early fast-acting component associated with object formation and a later component that acts through object substitution. So far, masking paradigms used in schizophrenia research have been unable to separate these two processes.
Method
We administered three visual processing paradigms (location masking with forward and backward masking, four-dot backward masking and a cuing task) to 136 patients with schizophrenia or schizoaffective disorder and 79 healthy controls. A psychophysical procedure was used to match subjects on identification of an unmasked target prior to location masking. Location masking interrupts object formation, four-dot masking task works through masking by object substitution and the cuing task measures iconic decay.
Results
Patients showed impairment on location masking after being matched for input threshold, similar to previous reports. After correcting for age, patients showed lower performance on four-dot masking than controls, but the groups did not differ on the cuing task.
Conclusions
Patients with schizophrenia showed lower performance when masking was specific to object substitution. The difference in object substitution masking was not due to a difference in rate of iconic decay, which was comparable in the two groups. These results suggest that, despite normal iconic decay rates, individuals with schizophrenia show impairment in a paradigm of masking by object substitution that did not also involve disruption of object formation.
We review the interaction in intermediate and high mass stars between their evolution and magnetic and chemical properties. We describe the theory of Ap-star ‘fossil’ fields, before touching on the expected secular diffusive processes which give rise to evolution of the field. We then present recent results from a spectropolarimetric survey of Herbig Ae/Be stars, showing that magnetic fields of the kind seen on the main-sequence already exist during the pre-main sequence phase, in agreement with fossil field theory, and that the origin of the slow rotation of Ap/Bp stars also lies early in the pre-main sequence evolution; we also present results confirming a lack of stars with fields below a few hundred gauss. We then seek which macroscopic motions compete with atomic diffusion in determining the surface abundances of AmFm stars. While turbulent transport and mass loss, in competition with atomic diffusion, are both able to explain observed surface abundances, the interior abundance distribution is different enough to potentially lead to a test using asterosismology. Finally we review progress on the turbulence-driving and mixing processes in stellar radiative zones.
For the sensitive detection of eggs of Echinococcus multilocularis in fox faeces by PCR we have evaluated a method based on the previous concentration of helminth eggs by a combination of sequential sieving of faecal samples and flotation of the eggs in zinc chloride solution. The eggs were microscopically detected in the fractions retained in 40 and 20µm mesh sieves. DNA of the taeniid eggs retained in the 20 µm sieve was obtained after alkaline lysis and PCR was performed using E. multilocularis species-specific primers. Compared to the parasitological findings after examination of the small intestines of the foxes, the specificity of the PCR was 100% (no false-positive result with 20 foxes free of E. multilocularis) and the sensitivity was 94% (33 positive results from total 35 foxes proven to be infected with E. multilocularis). Both false-negative results were obtained with faeces from foxes harbouring immature worms. Using faecal volumes between 2 and 20 ml, no inhibition of PCR was observed as was demonstrated by the amplification of size-modified target in parallel reactions. The tests were undertaken with fresh faeces stored in 70% ethanol, but egg detection by PCR was also possible after inactivation of eggs by freezing the faeces at −80°C for one week or by incubation at +70°C for 2 h.
Magnetic field and their related dynamical effects are thought to be important in stellar radiation zones. For instance, it has been suggested that a dynamo, sustained by a m = 1 MHD instability of toroidal magnetic fields (discovered by Tayler in 1973), could lead to a strong transport of angular momentum and of chemicals in such stable regions. We wish here to recall the different magnetic transport processes present in radiative zone and show how the dynamo can operate by recalling the conditions required to close the dynamo loop (BPol → BTor → BPol). Helped by high-resolution 3D MHD simulations using the ASH code in the solar case, we confirm the existence of the m = 1 instability, study its non-linear saturation, but we do not detect, up to a magnetic Reylnods number of 105, any dynamo action.
Magnetic field is an essential dynamical process in stellar radiation zones. Moreover, it has been suggested that a dynamo action, sustained by a MHD instability which affects the toroidal axisymmetric magnetic field, could lead to a strong transport of angular momentum and of chemicals in such regions. Here, we recall the different magnetic transport and mixing processes in radiative regions. Next, we show that the dynamo cannot operate as described by Spruit (2002) and recall the condition required to close the dynamo loop. We perform high-resolution 3D simulations with the ASH code, where we observe indeed the MHD instability, but where we do not detect any dynamo action, contrary to J. Braithwaite (2006). We conclude on the picture we get for magnetic transport mechanisms in radiation zones and the associated consequences for stellar evolution.
The use of chemical energy in the EAF has increased significantly inrecent years, both for enhancing productivity and reducing electricityconsumption. However, these tools are operated following pre-setpatterns, without any feedback information from the process. Thisleads both to non-optimized operations and to occasional blowbackproblems, resulting in damages to burners, lances, watercooledpanels and refractory lining. CRM has developed an on-line “distance-to-scrap” measurementtechnique that can be fitted inside annular burners. This measurementallows monitoring the melting of scrap in front of each burner,and thus detecting blow-back occurrences before any damage iscreated. This sensor was successfully tested in the Esch-Belval steelplant of ArcelorMittal Profil Luxembourg. Industrial implementation isunder way.
With the first light of COROT, the preparation of KEPLER and the future helioseismology spatial projects such as GOLF-NG, a coherent picture of the evolution of rotating stars from their birth to their death is needed. We describe here the modelling of the macroscopic transport of angular momentum and matter in stellar interiors that we have undertaken to reach this goal. First, we recall in detail the dynamical processes that are driving these mechanisms in rotating stars and the theoretical advances we have achieved. Then, we present our new results of numerical simulations which allow us to follow in 2D the secular hydrodynamics of rotating stars, assuming that anisotropic turbulence enforces a shellular rotation law. Finally, we show how this work is leading to a dynamical vision of the Hertzsprung-Russel diagram with the support of asteroseismology and helioseismology, seismic observables giving constraints on the modelling of the internal transport and mixing processes. In conclusion, we present the different processes that should be studied in the near future to improve our description of stellar radiation zones.