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Narrowleaf goldenrod [Euthamia graminifolia (L.) Nutt.] is the most common goldenrod species in lowbush blueberry (Vaccinium angustifolium Aiton) fields in Nova Scotia, Canada. Knowledge of ramet emergence and phenological development of this weed is limited, and it is unknown if seedling emergence contributes to the maintenance of established populations. The objectives of this research were to (1) develop predictive GDD models for E. graminifolia ramet emergence and phenological development, (2) determine whether E. graminifolia forms seedbanks in lowbush blueberry fields, and (3) establish whether E. graminifolia seedlings emerge in lowbush blueberry fields. Cumulative E. graminifolia ramet emergence was explained as a function of GDD using a four-parameter Weibull equation that predicted emergence to begin at 72 GDD and 90% emergence to occur at 458 GDD. Cumulative ramets at the flower bud and flowering stages were explained as a function of GDD using a three-parameter Gompertz equation that predicted initiation of the flower bud and flowering stages at 644 and 1,369 GDD, respectively, and 90% of ramets at the flower bud and flowering stages at 1,522 and 2,113 GDD, respectively. Cumulative E. graminifolia seedling emergence ranged from 2.4 ± 0.8 to 4 ± 1 seedlings m−2, suggesting limited seedling emergence in lowbush blueberry fields. Seedling density from soil core samples, however, ranged from 38 ± 25 to 10,940 ± 1,456 seedlings m−2. These results suggest that E. graminifolia forms seedbanks in lowbush blueberry fields, despite the low levels of seedling emergence observed. Euthamia graminifolia seedling management should therefore be considered in current weed control programs, and growers can use the developed GDD models to aid the management of established plants.
To provide an up-to-date review of existing and current literature in the field of radiological and nuclear disasters to support the needs of research applications for health care and public health preparedness and response.
Methods
A systematic literature search using 4 databases to identify articles which included a multitude of topics relevant to preparedness for nuclear and radiological disasters. One hundred articles that met inclusion criteria were summarized into 7 themes addressing medical and health care preparedness for nuclear and radiological events.
Results
The review generated evidence supporting and defining various measures health care and government entities can take to improve nuclear and radiological disaster readiness and responsiveness in health systems. Strengthening preventive measures and policies, prehospital and hospital mechanisms, training and education, regional collaboration, communication, and infrastructure support were the main gaps identified.
Conclusions
An overarching concern regarding the inadequacies of the modern health care system’s radiological disaster preparedness was a clear-cut conclusion from the literature. The major challenges and proposed solutions for public safety to the growing threat of radiologic disasters were identified.
To successfully recruit and retain faculty members from underrepresented backgrounds (URBs), we need to understand the factors that attract them to research careers in the first place. However, scholarship in this area has focused largely on students who are contemplating research careers rather than faculty members who are currently in such careers.
Methods:
This study explores the career motivations of early-career health researchers (faculty members and postdoctoral fellows) from URBs. It was conducted as part of a cluster randomized trial across 25 academic institutions investigating a support intervention. We conducted 1-hour semi-structured qualitative interviews with scholars from URBs in both the intervention and control arms of the trial. To our knowledge, this is the largest qualitative study of early-career faculty members from URBs to date.
Results:
Seventy-eight individuals were interviewed. Our analysis revealed six key themes pertinent to participants’ motivations to pursue research careers: (1) love of science; (2) making a larger impact; (3) happenstance and economic considerations; (4) family, community, and a path out of poverty; (5) the role of mentors and role models; and (6) support programs for scholars from URBs.
Conclusions:
Our results align with prior studies while offering new insights into the motivations of URB faculty members in research careers. These insights can and should inform the design of programs to both recruit and retain URM faculty members in research careers.
This cross-sectional study examined the association between diet price and diet quality in a national sample of Australian adults (n 1956). Diet recall data from the 2020 International Food Policy Study were linked to a national food and beverage price dataset. Daily diet price was calculated by summing the median non-promotional prices of all foods and beverages recorded in diet recall data, priced per gram (or millilitre) and adjusted for edible portions. Diet quality was determined using the Australian Dietary Guideline Index 2013 (scored out of 115). Linear regression models tested the association between the diet price (per dollar and per ten-dollar increments) and diet quality, adjusted for education, age and sex. A positive association was observed, where diet quality increased by 0·09 units (95 % CI 0·05, 0·14) for every $AU 1 increase in diet price. Daily diet price explained approximately 8 % of the variation in diet quality across the sample (R2 = 0·08). When categorised in ten-dollar increments, participants with diet prices < $AU 10/d had a lower mean diet quality score (51·96) compared with all other diet price categories, 5–6 points lower than those whose diet was > $30/d. Diet price appeared to be a modest yet significant determinant of diet quality for Australian adults in 2020. Additional analyses are needed to investigate these associations during recent food inflation. As diet quality appears to be lowest for people who spend the least on food, government action to increase priority communities’ food budgets may help improve the nutritional quality of population diets.
This chapter explores a form of anticolonial resistance that has gone relatively unnoticed by social theorists – insurrections aboard slaving ships. How might social theorists effectively represent, theorize, and contextualize these moments of anticolonial action? Drawing on the materials from the newly opened Lloyd’s archives, we discuss the importance of the insurance archive to histories of slavery and how these materials – despite their colonial ontologies – can offer novel understandings of anticolonial action. The materials permit scholars to uncover a complex set of financial logics that convey multiple different meanings about the category of the human and allow social theorists to ask different questions. Even the smallest details in the most highly localized spaces can provide insight into the nature of resistance and revolution.
Repetitive negative thinking (RNT) in major depressive disorder (MDD) involves a persistent focus on negative self-related experiences. Resting-state fMRI shows that the functional connectivity (FC) between the anterior insula and the superior temporal sulcus is associated with RNT intensity. This study examines how insular FC patterns differ between resting state and RNT induction in MDD and healthy control (HC) participants.
Methods
Forty-one individuals with MDD and 28 HCs (total n = 69) underwent resting-state and RNT-induction fMRI scans. Seed-to-whole brain analysis using insular subregions as seeds was performed.
Results
No diagnosis-by-run interaction effects were observed across insular subregions. MDD participants showed greater FC between the bilateral anterior, middle, and posterior insular regions and the cerebellum (z = 4.31–6.15). During RNT induction, both MDD and HC participants demonstrated increased FC between bilateral anterior/middle insula and prefrontal cortices, parietal lobes, posterior cingulate cortex (PCC), and medial temporal gyrus, encompassing the STS (z = 4.47–8.31). In exploratory correlation analyses, higher trait RNT was associated with increased FC between the right dorsal anterior/middle insula and the PCC, middle temporal gyrus, and orbital frontal gyrus in MDD participants (z = 4.31–6.15). Greater state RNT was linked to increased FC in similar insular regions, as well as the bilateral angular gyrus and right middle temporal gyrus (z = 4.47–8.31).
Conclusions
Hyperconnectivity in insula subregions during active rumination, especially involving the default mode network and salience network, supports theories of heightened self-focused and negative emotional processing in depression. These findings emphasize the neural basis of RNT when actively elicited in MDD.
Scientific teams that are comprised of different types of researchers have higher research productivity, and there is a need for evidence-based methods to improve the biomedical research workforce. Building Up a Biomedical Research Workforce (Building Up) was a multi-center, cluster-randomized, unblinded controlled trial with one intervention arm and one control arm, conducted at 25 United States academic medical centers. The authors tested the hypothesis that participants from backgrounds underrepresented in science who are randomized to the intervention will have greater numbers of peer-reviewed publications and increased Psychological Capital, compared to the control group.
Methods:
The study included a 10-month intervention period and follow-up assessments occurring one, two, and three years after the intervention began. The intervention arm received a 10-month intervention with monthly meetings, near-peer mentoring, networking opportunities, and grant- and scientific-writing coursework. Participants in the control arm experienced the usual forms of mentoring, networking, and coursework that their institutions provided.
Results:
Of the 220 participants who completed the pre-intervention assessment (98% of all enrolled participants), 71% completed the post-intervention assessment at year 1, 60% at year 2, and 66% at year 3. Individuals in the intervention arm had significantly higher levels of self-efficacy, resilience, and optimism in the three years following the start of the intervention, compared to the control arm.
Discussion:
This finding suggests that the Building Up intervention can increase participants’ Psychological Capital.
Understanding the properties of lower-carbon concrete products is essential for their effective utilization. Insufficient empirical test data hinders practical adoption of these emerging products, and a lack of training data limits the effectiveness of current machine learning approaches for property prediction. This work employs a random forest machine learning model combined with a just-in-time approach, utilizing newly available data throughout the concrete lifecycle to enhance predictions of 28 and 56 day concrete strength. The machine learning hyperparameters and inputs are optimized through a novel unified metric that combines prediction accuracy and uncertainty estimates through the coefficient of determination and the distribution of uncertainty quality. This study concludes that optimizing solely for accuracy selects a different model than optimizing with the proposed unified accuracy and uncertainty metric. Experimental validation compares the 56-day strength of two previously unseen concrete mixes to the machine learning predictions. Even with the sparse dataset, predictions of 56-day strength for the two mixes were experimentally validated to within 90% confidence interval when using slump as an input and further improved by using 28-day strength.
We co-designed a bee sequence with a specialist primary science teacher at an Australian government school. Year 6 students learned about European honeybees and Australian native bees, including through Cli-Fi. In this paper, we explore the pedagogical power of providing students with opportunities to create Cli-Fi about bee futures in the Anthropocene. We present and thematically analyse examples of students’ bee Cli-Fi to argue that they generated these narratives to express how we ought to value bees and how we ought to conduct ourselves towards bees to realise more desirable futures. We propose that these students were futuring as normative myths. Students generated dystopian views of bee futures in adopting a human perspective, but also present were glimmers of hope for a more positive outlook that embraced more-than-human perspectives. We adopt a pragmatist semiotic approach to propose that these young people’s bee Cli-Fi constituted normative claims about the future of bees, as they outlined the aesthetics (how and what we ought to value) and ethics (how and in what way we ought to act) of humans caring for bees in an epoch of polycrisis. We suggest that Cli-Fi ought to be an integral part of climate change education in empowering students to assert their agency.
Efficacy of gastric inlet patch (GIP) ablation using argon plasma coagulation (APC) for patients presenting with persistent throat symptoms was evaluated.
Methods
Retrospective observational study from a single university hospital. Consecutive patients who had GIP ablation for persistent throat symptoms between 01/10/2018-31/10/2023 were reviewed and patients who met all of the set inclusion and exclusion criteria were included in this study for analysis.
Results
50% (n = 18/36) of patients responded to APC ablation (median follow-up 3 months) with their post-ablation GETS score decreasing by 30-100%. Long-term follow-up results could be obtained from 22 patients (n = 22/36) and 75% (n = 9/12) had their clinical effects maintained (median follow-up 4.5 years; range 2.7–5.8 years).
Conclusion
GIP ablation can be a very effective treatment for patients with persistent throat symptoms with its therapeutic effects long-lasting. Future studies should focus on evaluating the optimal patient selection process for GIP ablation for persistent throat symptoms.
Governments are increasingly implementing policies to improve population diets, despite food industry resistance to regulation that may reduce their profits from sales of unhealthy foods. However, retail food environments remain an important target for policy action. This study analysed publicly available responses of industry actors to two public consultations on regulatory options for restricting unhealthy food price and placement promotions in retail outlets in Scotland.
Design:
We conducted a qualitative content analysis guided by the Policy Dystopia Model to identify the discursive (argument-based) and instrumental (tactic-based) strategies used by industry actors to counter the proposed food retail policies.
Setting:
Scotland, UK, 2017–2019.
Participants:
N/A.
Results:
Most food and retail industry responses opposed the policy proposals. Discursive strategies employed by these actors commonly highlighted the potential costs to the economy, their industries and the public in the context of a financial crisis and disputed the potential health benefits of the proposals. They claimed that existing efforts to improve population diets, such as nutritional reformulation, would be undermined. Instrumental strategies included using unsubstantiated and misleading claims, building a coordinated narrative focused on key opposing arguments and seeking further involvement in policy decision-making.
Conclusions:
These findings can be used by public health actors to anticipate and prepare for industry opposition when developing policies targeted at reducing the promotion of unhealthy food in retail settings. Government action should ensure robust management of conflicts of interest and establishment of guidance for the use of supporting evidence as part of the public health policy process.
The First Large Absorption Survey in H i (FLASH) is a large-area radio survey for neutral hydrogen in and around galaxies in the intermediate redshift range $0.4\lt z\lt1.0$, using the 21-cm H i absorption line as a probe of cold neutral gas. The survey uses the ASKAP radio telescope and will cover 24,000 deg$^2$ of sky over the next five years. FLASH breaks new ground in two ways – it is the first large H i absorption survey to be carried out without any optical preselection of targets, and we use an automated Bayesian line-finding tool to search through large datasets and assign a statistical significance to potential line detections. Two Pilot Surveys, covering around 3000 deg$^2$ of sky, were carried out in 2019-22 to test and verify the strategy for the full FLASH survey. The processed data products from these Pilot Surveys (spectral-line cubes, continuum images, and catalogues) are public and available online. In this paper, we describe the FLASH spectral-line and continuum data products and discuss the quality of the H i spectra and the completeness of our automated line search. Finally, we present a set of 30 new H i absorption lines that were robustly detected in the Pilot Surveys, almost doubling the number of known H i absorption systems at $0.4\lt z\lt1$. The detected lines span a wide range in H i optical depth, including three lines with a peak optical depth $\tau\gt1$, and appear to be a mixture of intervening and associated systems. Interestingly, around two-thirds of the lines found in this untargeted sample are detected against sources with a peaked-spectrum radio continuum, which are only a minor (5–20%) fraction of the overall radio-source population. The detection rate for H i absorption lines in the Pilot Surveys (0.3 to 0.5 lines per 40 deg$^2$ ASKAP field) is a factor of two below the expected value. One possible reason for this is the presence of a range of spectral-line artefacts in the Pilot Survey data that have now been mitigated and are not expected to recur in the full FLASH survey. A future paper in this series will discuss the host galaxies of the H i absorption systems identified here.
Root research on field-grown crops is hindered by the difficulty of estimating root biomass in soil. Root washing, the current standard method is laborious and expensive. Biochemical methods to quantify root biomass in soil, targeting species-specific DNA, have potential as a more efficient assay. We combined an efficient DNA extraction method, designed specifically to extract DNA from soil, with well-established quantitative PCR methods to estimate the root biomass of 22 wheat varieties grown in field trials over two seasons. We also developed an assay for estimating root biomass for black-grass, a common weed of wheat cultivation.
Methods
Two robust qPCR assays were developed to estimate the quantity of plant root DNA in soil samples, one specific to wheat and barley, and a second specific to black-grass.
Results
The DNA qPCR method was comparable, with high correlations, with the results of root washing from soil cores taken from winter wheat field trials. The DNA qPCR assay showed both variety and depth as significant factors in the distribution of root biomass in replicated field trials.
Conclusions
The results suggest that these DNA qPCR assays are a useful, high-throughput tool for investigating the genetic basis of wheat root biomass distribution in field-grown crops, and the impact of black-grass root systems on crop production.
The purpose of this research was to understand perceptions and experiences of inclusion among underrepresented early-career biomedical researchers (postdoctoral fellows and early-career faculty) enrolled in the Building Up study. Because inclusion is vital to job satisfaction and engagement, our goal was to shed light on aspects of and barriers to inclusion within the academic workforce.
Methods:
We used qualitative interviews to assess workplace experiences of 25 underrepresented postdoctoral fellows and early-career faculty including: their daily work experiences; sense of the workplace culture within the institutions; experiences with microaggressions, racism, and discrimination; and whether the diversity, equity, and inclusion (DEI) policies and practices at their institution enhanced their experiences. Using qualitative methods, we identified themes that highlighted high-level characteristics of inclusion.
Results:
Four distinct themes were identified: (1) participants appreciated the flexibility, versatility, and sense of fulfillment of their positions which enhanced feelings of inclusion; (2) greater psychological safety led to a greater sense of belonging to a research community; (3) participants had varied experiences of inclusion in the presence of microaggressions, racism, and discrimination; and (4) access to opportunities and resources increased feelings of value within the workplace.
Discussion:
Our findings provide new insight into how inclusion is experienced within the institution among underrepresented early-career biomedical researchers. This research points to specific approaches that could be used to enhance experiences of inclusion and to address barriers. More research is needed to understand how to accomplish a balance between the two, so that perceptions of inclusion outweigh negative experiences.
Following inter-/transdisciplinary ideas, environmental education inherently collaborates with other subjects, including physical education. As the work with other subjects might be jeopardised by differing worldviews and paradigms, it is worth illuminating compatible and incompatible positions for inter-/transdisciplinary work. In physical education, the concept of physical literacy (PL) has recently gained considerable attention and adopts a student-centred perspective on human existence and learning. Therefore, the goal of the present narrative integrative review was to review the existing literature at the nexus between physical education and environmental education through a PL lens (five pre-defined concept assumptions). After screening for eligibility, a total of 129 articles were assigned to five different thematic categories: (a) conceptual discussion/argumentative patterns, (b) curricular discussion and international comparisons, (c) programming/intervention content, (d) teacher and enabler perspectives and (e) student outcomes/perspectives. The synthesis revealed that PL can harmonise with the educative work when respecting the disciplinary interests of both physical education and environmental education. However, few intervention studies translate the holistic PL claims into interventions. Accordingly, evaluations with teachers or students less frequently integrated holistic learning experiences in line with PL. In summary, previous research at the nexus has not yet exhausted its full inter-/transdisciplinary potential.
The rising incidence of neurodegenerative diseases in an ageing global population has shifted research focus towards modifiable risk factors, such as diet. Despite potential links between dietary patterns and brain health, inconsistencies in neuroimaging outcomes underscore a gap in understanding how diet impacts brain ageing. This study explores the relationship between three dietary patterns – Mediterranean, Dietary Approaches to Stop Hypertension (DASH) and Mediterranean-DASH Intervention for Neurodegenerative Delay – and cognitive outcomes as well as brain connectivity. The study aimed to assess the association of these diets with brain structure and cognitive function, involving a middle-aged healthy group and an older cohort with subjective cognitive decline. The study included cognitive assessments and diffusion-weighted MRI data to analyse white matter microstructural integrity. Participants comprised fifty-five older individuals with subjective cognitive decline (54·5 % female, mean age = 64) and fifty-two healthy middle-aged individuals (48·1 % female, mean age = 53). Age inversely correlated with certain cognitive functions and global brain metrics, across both cohorts. Adherence to the Mediterranean, DASH and Mediterranean-DASH Intervention for Neurodegenerative Delay diets showed no significant cognitive or global brain metric improvements after adjusting for covariates (age, education, BMI). Network-based statistics analysis revealed differences in brain subnetworks based on DASH diet adherence levels in the subjective cognitive decline cohort. In the healthy cohort, lower white matter connectivity was associated with reduced adherence to Mediterranean-DASH Intervention for Neurodegenerative Delay and DASH diets. Ultimately, the study found no strong evidence connecting dietary patterns to cognitive or brain connectivity outcomes. Future research should focus on longitudinal studies and refine dietary assessments.
Head and neck cancer (HNC) often requires complex management and care. While the primary goal of treatment is curative, some advanced cases require consideration of non-curative pathways to optimize patients’ quality of life (QOL) and survival. This narrative review describes important aspects of palliative care and highlights strategies for employing these non-curative options in HNC.
Methods
We identified peer-reviewed articles on the state of palliative care in HNC and its implementation. We searched for articles using terms including “palliative care,” “non-curative care,” “comfort care,” “head and neck cancer,” and “head and neck squamous cell carcinoma.”
Results
HNC is associated with a high disease burden; patients report high levels of pain, and both disease and treatment often compromise ability to carry out activities of daily living. There exist several non-curative routes of treatment, including palliation of symptoms, acute end-of-life (EOL) care, and hospice and home care. These care options provide comfort and optimize QOL of patients. Unfortunately, non-curative care could be misconstrued as withdrawal of treatment, or the provider team “giving up” on patient; these misconception can discourage patients from embracing palliative measures designed to alleviate symptom burden. Proper physician–patient communication, normalization, and early incorporation of these non-curative strategies into mainstream treatment could potentially ease patient concerns, and, eventually in EOL cases, help patients achieve dignified deaths.
Significance of results
Patients with HNC have unique palliative care needs due to their complex treatment and symptom burden. Early incorporation of non-curative plans such as palliative care alongside active treatment could help reduce symptom burden. Clinicians should strive to build trusting relationships with patients with HNC and effectively communicate with them about palliative care options. Guidelines that include such recommendations can help physicians regularly introduce palliation into the realm of active HNC treatment for advanced/incurable disease.
Birds possess the most diverse assemblage of haemosporidian parasites, although the true diversity is unknown due to high genetic diversity and insufficient sampling across all avian clades. Waterfowl (Order Anseriformes) are an ideal group to discover hidden parasite diversity and examine the role of host ecology in parasite transmission. Waterfowl contain 2 distinct feeding guilds, dabbling and diving, which differ in niche utilization that likely alters vector encounter rates and haemosporidian parasite risk. To determine the role of feeding guild in haemosporidian parasitism we analysed 223 blood samples collected by hunters from the upper Midwest of the United States from 2017 to 2019. Fifty-four individuals were infected by haemosporidian parasites (24·2% prevalence). Infection prevalence differed significantly between dabbling (34·9%, n = 109) and diving (14·0%, n = 114) ducks. Feeding guild was the only host trait that could predict haemosporidian infection risk, with a significantly higher risk in dabbling ducks. Twenty-four haemosporidian lineages were identified, with 9 identified for the first time. Thirteen lineages were found only in dabbling ducks, 5 only in diving ducks and 6 in both feeding guilds. Community analysis showed that each feeding guild harboured a unique parasite community. There was no phylogenetic signal of feeding guild within a phylogenetic reconstruction of North American waterfowl haemosporidian lineages. Our results demonstrate that waterfowl contain a diverse and distinct community of haemosporidian parasites. The unique composition of each feeding guild determines not only haemosporidian infection risk but also community structure. This is the first report of such an impact for waterfowl feeding guilds.
We have conducted a widefield, wideband, snapshot survey using the Australian SKA Pathfinder (ASKAP) referred to as the Rapid ASKAP Continuum Survey (RACS). RACS covers $\approx 90$% of the sky, with multiple observing epochs in three frequency bands sampling the ASKAP frequency range of 700–1 800 MHz. This paper describes the third major epoch at 1 655.5 MHz, RACS-high, and the subsequent imaging and catalogue data release. The RACS-high observations at 1 655.5 MHz are otherwise similar to the previously released RACS-mid (at 1 367.5 MHz) and were calibrated and imaged with minimal changes. From the 1 493 images covering the sky up to declination $\approx +48^\circ$, we present a catalogue of 2 677 509 radio sources. The catalogue is constructed from images with a median root-mean-square noise of $\approx 195$$\unicode{x03BC}$Jy PSF$^{-1}$ (point-spread function) and a median angular resolution of $11{\stackrel{\prime\prime}{\raise-0pt\hbox{.}}}8 \times 8{\stackrel{\prime\prime}{\raise-0pt\hbox{.}}}1$. The overall reliability of the catalogue is estimated to be 99.18%, and we find a decrease in reliability as angular resolution improves. We estimate the brightness scale to be accurate to 10%, and the astrometric accuracy to be within $\approx 0{\stackrel{\prime\prime}{\raise-0pt\hbox{.}}}6$ in right ascension and $\approx 0{\stackrel{\prime\prime}{\raise-0pt\hbox{.}}}7$ in declination after correction of a systematic declination-dependent offset. All data products from RACS-high, including calibrated visibility datasets, images from individual observations, full-sensitivity mosaics, and the all-sky catalogue are available at the CSIRO ASKAP Science Data Archive.