Closed-loop control of an amplifier flow is experimentally investigated. A feed-forward algorithm is implemented to control the flow downstream of a backward-facing step (BFS) perturbed by upstream perturbations. Upstream and downstream data are extracted from real-time velocity fields to compute an ARMAX model used to effect actuation. This work, done at Reynolds number 430, investigates the practical feasibility of this approach which has shown great promise in a recent numerical study by Hervé et al. (J. Fluid Mech., vol. 702, 2012, pp. 26–58). The linear nature of the regime is checked, two-dimensional upstream perturbations are introduced, and the degree to which the flow can be controlled is quantified. The resulting actuation is able to effectively reduce downstream energy levels and fluctuations. The limitations and difficulties of applying such an approach to an experiment are also discussed.