After six years, this will be my tenth survey review here – and last. Since these reviews are intended to enable some sense of the state of the evolving field, I thought I might in this swansong try to offer not just the usual smorgasbord of Roman entertainment but an attempt at a synthesis of five key directions in research. A whole host of qualifications immediately raise their heads, of course – anglophone dominance, incomplete representation of presses, and my own not inconsiderable limitations of time, ability, and interest. Still, since opportunities for such overviews over time are sparse, the exercise will hopefully be instructive even so hamstrung.

Family caregivers are essential inpatient pediatric care partners, yet their handwashing knowledge and compliance are rarely studied. Through hand hygiene audits and self-administered questionnaires, we observed 9% compliance, significantly lower than self-reported practice. We suggest interventions to improve caregiver handwashing behaviors to decrease infection transmission risk to hospitalized children.

The figure of the Roman emperor – ubiquitous yet ever-elusive – remains the flame to which Roman historians are ever drawn. And Fergus Millar's The Emperor in the Roman World remains the yardstick against which all subsequent efforts are judged, and with which they are all inevitably in dialogue. That is true too of Caesar Rules, the major new offering from Olivier Hekster, a one-time doctoral student of Millar's, and now one of the leading contenders for his crown. Hekster's core interest is what the emperor was; in particular, how this institution could survive and adapt to changing circumstances despite the fact that formally it did not exist, certainly was not defined, and practically existed in a society antithetical on principle to both monarchy and change. Hekster finds the key for this long-worried lock in ‘the presentation and perception of power’ (10), and in particular the expectations – from all sides, and at all times – that both consolidated and constrained emperors’ authority. To demonstrate this he conceives a largely unprecedented ambition in this context: to consider source material in all media from the late Republic to the reign of Justinian.

Do you want to hear something worth knowing? If so, you're in luck, because Pliny the Elder has 20,000 such nuggets ready for your delectation. Even better, one of the elder statesmen of Roman history, Richard Saller, has provided a fresh study of them in his new book, Pliny's Roman Economy. Saller is famous for publications that have painted in broad brush strokes the landscape of Roman economic and social history as we now understand it. Here, instead, he offers a brief, focused study of a single author, albeit one whose Natural History is of extraordinarily ambitious scope. Published in ‘The Princeton Economic History of the Western World’ series, this is a book for both classicists and economic historians with a focused aim: to use Pliny to intervene in the long-standing debate over whether the Roman imperial economy enjoyed sustainable growth in the first two centuries ce (behind which lurks, as Saller notes, the more existential question as to whether the oppression of the Roman imperial project came with benefits). This question arises from a controversial methodological contention – that scholars’ efforts to develop sophisticated proxies to enable quantitative assessment of ancient economic growth (now largely associated with New Institutional Economics) have so far failed, and thus that we should return, at least in part, to more traditional use of literary sources: ‘at this point none [of those proxies] is reliable enough to justify neglecting our aristocratic authors’ (3). Pliny is particularly interesting here because eighteenth-century encyclopaedias have been seen (in part by the series editor, Joel Mokyr) as part of a culture of innovation that in turn fed the pronounced economic growth of that period.

Robots and inertial measurement units (IMUs) are typically calibrated independently. IMUs are placed in purpose-built, expensive automated test rigs. Robot poses are typically measured using highly accurate (and thus expensive) tracking systems. In this paper, we present a quick, easy, and inexpensive new approach to calibrate both simultaneously, simply by attaching the IMU anywhere on the robot’s end-effector and moving the robot continuously through space. Our approach provides a fast and inexpensive alternative to both robot and IMU calibration, without any external measurement systems. We accomplish this using continuous-time batch estimation, providing statistically optimal solutions. Under Gaussian assumptions, we show that this becomes a nonlinear least-squares problem and analyze the structure of the associated Jacobian. Our methods are validated both numerically and experimentally and compared to standard individual robot and IMU calibration methods.

Another bumper edition, again by way of apology for absenteeism in the spring issue (though this time due to paternity rather than plague). We begin with the latest Beard blockbuster. In her Twelve Caesars, based on her 2011 A.W. Mellon Lectures in the Fine Arts, Mary Beard turns her trademark combination of penetrating gaze and jovial tongue to the reception of the famed group of elite first-century ce Roman men who span a key moment in the transformation of ancient politics. Belying their importance for ancient historians and archaeologists, they have been rather neglected by art historians of later periods. With an extraordinarily wide lens, spanning from Alexander the Great to the 2017 modern art of Alison Wilding, Beard corrects that omission, demonstrating their central place in the history of Western art, and exploring not just how those emperors have been represented, repackaged, and reused, but what that says about the identities, worlds, and priorities of those who so mobilized them. The result is a tour de force of art and intellectual history. Not only is the reader presented with gloriously arcane anecdotes on almost every page, but their sum amounts to a sustained inquiry into the role that past power has played, and continues to play, in our history, politics, art, and culture.

After a focus on social and cultural history in the last issue, this issue's offerings return us to more traditional subjects – political institutions, and historiography. That spring review ended with religion, which is where we start here: an apposite reminder that religion pervades all aspects of the Roman world. It is precisely that principle which undergirds our first book, Dan-el Padilla Peralta's Divine Institutions. Padilla Peralta is interested, at root, in how the Roman state became such through the third and fourth centuries bce. That is a story usually told – in a tradition going back to the ancient historians themselves – via a swashbuckling tale of successive military campaigns. Padilla Peralta, however, sets that anachronistic narrativization aside, and instead builds a careful case that between the siege of Veii and the end of the Second Punic War ‘the Roman state remade and retooled itself into a republic defined and organized around a specific brand of institutionalized ritual practices and commitments’ (1). Specifically, he shows that the construction of temples and the public activities they facilitated were a key mechanism – one as important as warfare – by which the consensus necessary to state formation was generated:

A bumper edition this time, by way of apology for COVID-necessitated absenteeism in the autumn issue. The focus is on three pillars of social history – the economy (stupid), law, and religion. First up is Saskia Roselaar's second monograph, Italy's Economic Revolution. Roselaar sets out to trace the contribution made by economics to Italy's integration in the Roman Republic, focusing on the period after the ‘conquest’ of Italy (post 268 bce). Doing so necessitates two distinct steps: assessing, first, how economic contacts developed in this period, and second, whether and to what extent those contacts furthered the wider unification of Italy under Roman hegemony. Roselaar is influenced by New Institutional Economics (hereafter NIE), now ubiquitous in studies of the ancient economy. Her title may be an homage to Philip Kay's Rome's Economic Revolution, but the book itself is a challenge to that work, which in Roselaar's view neglects almost entirely the agency of the Italians in the period's economic transformation. For Roselaar, the Italians were as much the drivers of change as the Romans; indeed, it is this repeated conviction that unifies her chapters.

In order to maximize the utility of future studies of trilobite ontogeny, we propose a set of standard practices that relate to the collection, nomenclature, description, depiction, and interpretation of ontogenetic series inferred from articulated specimens belonging to individual species. In some cases, these suggestions may also apply to ontogenetic studies of other fossilized taxa.

Background: Hand hygiene (HH) is the most effective means of preventing healthcare-associated infections (HAI). HH improvement strategies primarily focus on healthcare staff, often overlooking the significant contribution of caregivers to HAI risk. We sought to understand caregivers’ HH knowledge and practices to identify improvement opportunities. Methods: A self-administered survey was developed and distributed to families from June to August 2019; open-ended questions and Likert scales assessed caregivers’ perceptions and practices regarding HH at home and in hospital. HH compliance audits of caregivers entering and exiting inpatient rooms were performed in the same time period. Results: Among 81 caregivers surveyed, median patient age was 4.0 (IQR, 0.9–13.0) years. This was the first admission for 42 patients (53.8%). During this admission, 22 (27.2%) patients had been admitted for ≤1 day and 45 (55.6%) for >3 days. Caregivers reported good knowledge of HH practice, with strongly positive responses to knowledge of HH moments (94%) and proper technique (96%). Caregivers recognized that HH is required of hospital visitors (96%) to protect others (99%) and prevent illness in hospital (93%). Responses were less consistent for performing HH before entering a hospital room (83%), after exiting the room (70%), or after coughing or sneezing (65%). The attitudes of caregivers of children above 2 years were equivocal regarding expectations of their child to wash hands upon entering (40%), or exiting (41%) the hospital room. Multivariable modeling identified higher self-reported HH compliance in caregivers during first admission to hospital, compared to subsequent admissions (OR, 3.15; 95% CI, 1.11–9.65). Reported barriers to HH included hand irritation (27.2%) and perceived HH frequency (18.5%). At the time of survey completion, 62 caregivers (77%) reported not having received HH information during their child’s admission from a healthcare provider or volunteer. Information was most commonly gained from posters (75%) and information in the room (31%). Most caregivers (58.0%) reported that they would prefer to receive HH information in the first 24 hours of admission. Among 200 audits, overall caregiver compliance with HH was 9%; HH before entering the room was 7.2% compared to 11.2% after exiting (P = .33). Conclusions: Reported caregiver knowledge of HH was not reflected in audited practice. Fewer than 1 in 4 had received HH information from healthcare staff. HH education in the hospital environment within the first day of admission provides an opportunity for caregivers to improve compliance as partners in HAI prevention and safer pediatric care.

Funding: None

Disclosures: None

Some questions never go out of fashion. My main focus in this issue is the spread of Roman power across the Mediterranean, with multiple new publications appearing on this oldest of subjects. First up is Dexter Hoyos’ Rome Victorious. This work of popular history aims to cover what Hoyos dubs in his subtitle The Irresistible Rise of the Roman Empire, though that is rather an odd choice, since Hoyos stresses that Rome's imperial efforts did not always succeed. Hoyos walks us through the unification of Italy and the acquisition of the Republican provinces in the first two chapters, taking the narrative up to the death of Caesar in 44 bc. The next two chapters consider the consequences of those conquests: what a province actually meant, how it was controlled, and the effects both on the new territories’ inhabitants and on Rome's social and political make-up. In Chapter 5, Hoyos turns to the extensive imperial efforts of Augustus and those around him; those of his successors over the next two centuries are dealt with in Chapter 6. Chapter 7 surveys the shifting make-up of the Romans as a result of their conquests, focusing on the spread of citizenship and the changing origins of senators, generals, and artists. Chapter 8 looks at legitimate and illegitimate rule in Rome's provinces, Chapter 9 considers both Rome's self-reflexivity on imperial questions and the view from those regions themselves, and Chapter 10 bolsters the latter by treating concrete resistance to Rome. Chapter 11 looks at the degree to which the provinces became Roman.

Reliable diagnosis of human helminth infection(s) is essential for ongoing disease surveillance and disease elimination. Current WHO-recommended diagnostic assays are unreliable in low-endemic near-elimination settings and typically involve the invasive, onerous and potentially hazardous sampling of bodily fluids such as stool and blood, as well as tissue via biopsy. In contrast, diagnosis by use of non-invasive urine sampling is generally painless, more convenient and low risk. It negates the need for specialist staff, can usually be obtained immediately upon request and is better accepted by patients. In some instances, urine-based diagnostic assays have also been shown to provide a more reliable diagnosis of infection when compared to traditional methods that require alternative and more invasive bodily samples, particularly in low-endemicity settings. Given these relative benefits, we identify and review current research literature to evaluate whether non-invasive urine sampling is currently exploited to its full potential in the development of diagnostic tools for human helminthiases. Though further development, assessment and validation are needed before their routine use in control programmes, low-cost, rapid and reliable assays capable of detecting transrenal helminth-derived antigens and cell-free DNA show excellent promise for future use at the point-of-care in high-, medium- and even low-endemicity elimination settings.

Provisia™ rice was developed recently by the BASF Corporation for control of grass weeds and is complementary to existing Clearfield® technology. Our previous research showed that resistance of Provisia™ rice to the acetyl coenzyme-A carboxylase herbicide quizalofop-p-ethyl (QPE) in laboratory and greenhouse environments is governed by a single dominant Mendelian gene. However, these results may not be consistent in different populations or field environments. Therefore, the first objective of the current research is to determine the inheritance of resistance to QPE in rice using different segregating populations evaluated under U.S. field environments. The second objective is to evaluate the response of QPE-resistant breeding lines to various herbicide concentrations at two U.S. locations. Chi-square tests of 12 F2 populations evaluated in Louisiana during 2014 and 2015 indicated that QPE seedling resistance at 240 g ai ha−1 was governed by a single dominant Mendelian gene with no observable maternal effects. Similar results were obtained in five F3 populations derived from the aforementioned F2 populations. Allele-specific SNP markers for QPE resistance also followed Mendelian segregation in the five F2 populations. For the second objective, six QPE-resistant inbred lines showed transient leaf injury at 1× (120 g ai ha−1) or 2× (240 g ai ha−1) field rates 7 and 21 d after treatment (DAT). However, a trend of reduced injury (recovery) from 7 through 33 DAT was observed for all breeding material. No differences in grain yield were found between untreated QPE-resistant lines and those treated with 1× or 2× QPE field rate. Single gene inheritance and good levels of QPE herbicide field resistance in different genetic populations suggest feasibility for rapid and effective development of new QPE-resistant varieties and effective stewardship of the Provisia™ technology.

As I write this, my wife and I are awaiting the imminent arrival of our first child. A natural tendency to find reassurance in research has led me to read a series of modern takes on fatherhood, which have proved of varying value. Imagine my delight, then, when Infancy and Earliest Childhood in the Roman World arrived on my desk. What better source of information? Unsurprisingly, What to Expect When You're Expecting this is not, though I have noted Soranus’ sage advice not to indulge pregnant women's cravings for charcoal or earth (Gyn. 1.15.48; 50). What Maureen Carroll's major new work does offer is the first systematic study of the youngest Romans, those in their first year of life, a topic which – despite the raft of work on the Roman family and life course over the last few decades – still stands in need of a synthesis. As well as evidence-gathering, Carroll's work has a central thesis; that ‘the evidence from archaeology, funerary epigraphy, and material culture marshalled in this study dispels the long-held notion that the very youngest infants were insignificant beings without a social persona whose lives were treated with indifference’ (7). Instead, what Carroll paints is a picture of the first year of life marked by both regular milestones – ‘from the naming day at eight or nine days, the official registration of birth by the thirtieth day, the release from swaddling bands at forty to sixty days, and the beginning of teething at six months, to the achievement of the child's first birthday’ (12) – and ongoing and substantial parental investment.

The first time I visited Pompeii, I was walking along one of its iconic paved streets when another visitor in front of me stumbled over a rough patch of pavement. Looking down resentfully, she turned to her friend and said in an irritated tone, ‘Look at this! They really need to do something about these roads…’. If that sore-toed tourist had found Eric Poehler's new book, The Traffic Systems of Pompeii, in the Pompeian gift shop, she would have been much illuminated. This long-gestated project represents an exciting new type of scholarship on the ancient world, using evidence gleaned from the scratched and rutted roads of Pompeii and other urban sites across the empire to expose both how ancient traffic worked and the constantly evolving negotiations between residents and government over its control.