Samuel Johnson's remark on the Quaker custom of allowing women to preach has become one of the most famous comments on female ministry in English literature. In the nineteenth century, women were perceived to be more religious than men and to be the guardians of their family's spiritual and moral development. This chapter focusses on women's ministry in the transatlantic Protestant world, in particular, the United States and Great Britain. Methodism, the most significant outgrowth of the Evangelical Revival, gave women positive roles in its early days. In 1912, the congregation received Vatican permission for its Indian Affiliated Sisters, a group established in the 1860s and canonically incorporated into the congregation in 1909, to be admitted to permanent vows and religious status. This history, particular and complex in its detail, typified the individual elements that made up the general and larger history of new religious orders in the nineteenth and twentieth centuries.