The aim of this work is to analyse the spatial distribution of the interregional migration in Spain during the period of economic development and structural change from the last decades of the XIXth century to 1930. The empirical approach reveals that a large part of migrants moved towards very close destinations. We also find that the spatial distribution of the internal migration shows a high spatial focusing, most in-migrants are moving selectively to only a few destinations while most out-migrants are leaving only a few origins. Finally, comparing with the less focused migration in 1960–1970, it is argued that these findings are related with the process of geographical concentration and the later dispersion of the Spanish economic development and employment opportunities during the XIX and XX centuries whose turning point is around 1950 or 1960.