The evolving COVID-19 pandemic and its likely consequences add to the already substantial psychosocial burden caused by global problems, existential threats and heightened uncertainty, which are increasingly confronting communities worldwide. Here we briefly outline three challenges for clinical psychiatry and research, related to coping with the social epidemiology of negative moods, stress and socially mediated traumatic experiences brought on by these adverse developments.

T1 and T2 relaxation times were examined in four pairs of monozygotic (MZ) twins discordant and concordant for schizophrenia with low and high genetic loading for the illness and five healthy control MZ twin pairs. Patients with schizophrenia (n = 11) showed significant prolongation in T1 relaxation times in the globus pallidus (GP) bilaterally (P < 0.005, Bonferroni corrected) when compared to 14 healthy MZ twins.

The method of analytic continuation in the coupling constant in combination with the use of statistical Padé approximation is applied to the determination of complex S-matrix poles, i.e. to the determination of resonance energy and widths. These parameters are of vital importance in many physical, chemical and biological processes. It is shown that an alternative to the method of analytic continuation in the coupling constant exists which in principle makes it possible to locate several resonances at once, in contrast to the original method which yields parameters of only one resonance. In addition the new approach appears to be less sensitive to the choice of the perturbation interaction used for the analytical continuation than the original method. In this paper both approaches are compared and tested for model analytic separable potential. It is shown that the new variant of the method of analytic continuation in the coupling constant is more robust and efficient than the original method and yields reasonable results even for data of limited accuracy.