This article examines the significance of a highly unusual stone statue discovered at Teynham, Kent, depicting a triton and a ketos. It discusses the context of the find in what appears to be a mausoleum complex adjacent to Watling Street. It provides a detailed description of the statue itself, alongside a petrological study, and places this in the context of other depictions of marine deities, particularly of tritons, in Britain and beyond. The article considers how the sculpture might have been placed on the exterior or interior of the tomb. It also discusses the possible occupant of the mausoleum (perhaps a villa owner or sailor), taking into account the possible symbolic value of the triton, either as signifier of afterlife beliefs or biographical achievement, as well as the ritual treatment of the statue after the tomb was dismantled. The wider context of the Teynham mausoleum is then analysed in terms of its location and form in relation to comparable monuments found in south-east England and better preserved tombs on the continent.

The locally made colour-coated ware vessel known as the Colchester Vase is argued to be a commissioned piece recording a performance in the town. The inscription on the vessel, cut pre-firing, names individual arena performers depicted en barbotine. One name, Memnon, is argued to be a ‘stage name’ taken from a protagonist in the Trojan war. The connection of another combatant, Valentinus, to the 30th legion is re-considered as evidence for gladiators linked to the Roman army. The Vase's final use was as a cremation urn. Osteological and isotopic analysis reveals the cremated remains to be those of a non-local male of 40+ years; unlikely to be one of the performers, he may nevertheless have been closely connected to the event.

A decorated copper-alloy key handle was recovered during excavation of a town house in Roman Leicester (Ratae Corieltavorum). The decoration comprises two groups of figures modelled in high relief: a bearded, unarmed man fighting with a lion, arranged above four naked male youths embracing one another in a protective manner. This decoration cannot be paralleled among other similarly elaborate Roman key handles and is best interpreted as a scene of damnatio ad bestias, although it does not directly replicate other known scenes of this punishment and spectacle. Other readings of the image are possible, depending on the context and perspective of the viewer as they handled the object.

There is growing interest globally in using real-world data (RWD) and real-world evidence (RWE) for health technology assessment (HTA). Optimal collection, analysis, and use of RWD/RWE to inform HTA requires a conceptual framework to standardize processes and ensure consistency. However, such framework is currently lacking in Asia, a region that is likely to benefit from RWD/RWE for at least two reasons. First, there is often limited Asian representation in clinical trials unless specifically conducted in Asian populations, and RWD may help to fill the evidence gap. Second, in a few Asian health systems, reimbursement decisions are not made at market entry; thus, allowing RWD/RWE to be collected to give more certainty about the effectiveness of technologies in the local setting and inform their appropriate use. Furthermore, an alignment of RWD/RWE policies across Asia would equip decision makers with context-relevant evidence, and improve timely patient access to new technologies. Using data collected from eleven health systems in Asia, this paper provides a review of the current landscape of RWD/RWE in Asia to inform HTA and explores a way forward to align policies within the region. This paper concludes with a proposal to establish an international collaboration among academics and HTA agencies in the region: the REAL World Data In ASia for HEalth Technology Assessment in Reimbursement (REALISE) working group, which seeks to develop a non-binding guidance document on the use of RWD/RWE to inform HTA for decision making in Asia.

A fragment of Roman monumental bronze sculpture was discovered near Lincoln in 2015 and reported to the Portable Antiquities Scheme. This note offers identification of the piece as an over-life-size finger, describes comparable examples and similar pieces from the local area, and makes suggestions as to the original form of the sculpture from which it may have derived. The statue's metallurgical characteristics and making, the possible context of display and the circumstances of deposition are also considered.

A fine-grained, up to 3-m-thick tephra bed in southwestern Saskatchewan, herein named Duncairn tephra (Dt), is derived from an early Pleistocene eruption in the Jemez Mountains volcanic field of New Mexico, requiring a trajectory of northward tephra dispersal of ~1500 km. An unusually low CaO content in its glass shards denies a source in the closer Yellowstone and Heise volcanic fields, whereas a Pleistocene tephra bed (LSMt) in the La Sal Mountains of Utah has a very similar glass chemistry to that of the Dt, supporting a more southerly source. Comprehensive characterization of these two distal tephra beds along with samples collected near the Valles caldera in New Mexico, including grain size, mineral assemblage, major- and trace-element composition of glass and minerals, paleomagnetism, and fission-track dating, justify this correlation. Two glass populations each exist in the Dt and LSMt. The proximal correlative of Dt1 is the plinian Tsankawi Pumice and co-ignimbritic ash of the first ignimbrite (Qbt1g) of the 1.24 Ma Tshirege Member of the Bandelier Tuff. The correlative of Dt2 and LSMt is the co-ignimbritic ash of Qbt2. Mixing of Dt1 and Dt2 probably occurred during northward transport in a jet stream.

OBJECTIVES/SPECIFIC AIMS: The objective of this project is the application of complex fusion models, which combine observed and modeled data, to areas with sparse monitoring networks with multiple chemical components is under-developed. Such models could provide improved accuracy and coverage for air quality measurement predictions, an area greatly limited by the amount of missing data. METHODS/STUDY POPULATION: This project focuses on the development of methods for improved estimation of pollutant concentrations when only sparse monitor networks are found. Sparse monitoring networks are defined as areas where fewer than three criteria air pollutants (based on EPA standards) are monitored. Particularly, a multivariate air pollutant statistical model to predict spatio-temporally resolved concentration fields for multiple pollutants simultaneously is developed and evaluated. The multivariate predictions allow monitored pollutants to inform the prediction of nonmonitored pollutants in sparse networks. RESULTS/ANTICIPATED RESULTS: Daily, ZIP code level pollutant concentration estimates will be provided for 8 pollutants across South Carolina, and goodness of fit metrics for model variants and previously established methods will be compared. DISCUSSION/SIGNIFICANCE OF IMPACT: These methods utilize only widely available data resources, meaning that the improved predictive accuracy of sparsely monitored pollutant concentrations can benefit future studies in any US area by improving estimation of health effects and saving resources needed for supplemental air pollutant monitoring campaigns. Our method for estimation attempts to improve predictive accuracy and data availability for sparsely monitored pollutants and areas.