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The interactions between two identical starting jets (twin-starting jets) are numerically investigated, focusing on the influence of initiation with temporal differences (the dimensionless time difference $\Delta \widetilde {t}\gt 0$) and spatial differences (the dimensionless axial distance $\Delta \widetilde {X}\gt 0$). Temporal differences mainly weaken the mutual interaction between the two leading vortex rings, while spatial differences weaken both the vortex-ring interactions and the influence of mutually induced pressure. In both cases, two leading vortex rings become non-coplanar, increasing their spatial distance along the jet direction and thereby weakening their mutual interaction. For propulsive characteristics, both temporal and spatial differences mitigate the reduction in average thrust caused by jet interactions, whereas only spatial differences significantly suppress the overall thrust fluctuations. In addition, both types of difference induce a net lateral force on the nozzle outer walls. The combined effects of $\Delta \widetilde {X}$ and the dimensionless nozzle spacing $S/D$, where $S$ is the distance between the axes of the two nozzles, and is the nozzle diameter. are incorporated into the mutually induced pressure model. Finally, the influence distance $S_3/D$ is introduced to quantify the weakening of vortex-ring interactions by temporal and spatial differences. This parameter also unifies the effects of $\Delta \widetilde {t}$ and $\Delta \widetilde {X}$, which contribute comparably to mitigating the reduction in the average thrust.
Alfalfa is a widely cultivated forage crop with high nutritional value, and it relies heavily on pollinators for successful reproduction owing to its keel petal structure. Numerous studies have shown the differences in pollinator diversity at different landscapes and/or regions, subsequently impacting plant reproduction. However, there is still insufficient evidence on variation in pollinator diversity at different sites with different landscapes and its effects on alfalfa reproduction. In this study, we investigated the diversity and abundance of floral visitors, and their impacts on alfalfa seed yield, across three sites represented by different landscapes, i.e. urban (Gongzhuling), semi-natural grassland (Changling), and farmland (Harbin) in north-eastern China. Our results showed that the diversity and abundance of all visitors, including bees in Changling were significantly higher than those of the other two sites. Changes in visitor diversity and abundance of alfalfa were closely related to climate variables, with positive effects of air temperature, and complex effects of precipitation. Meanwhile, the differences in pollinators may also be attributed to landscape types due to different habitat heterogeneity. Alfalfa seed yield in Changling was also significantly higher than that in the other two sites. Among these factors, air temperature, and diversity of floral visitors, particularly bees were positively related to alfalfa seed yield, indicating that pollinators combined with climate have an important contribution to changes in alfalfa seed yield. The findings from this study emphasise the importance of conserving pollinators to sustain and even enhance alfalfa yields, especially in the context of climate change and alterations in landscape types.
The effects arising from interactions between two identical starting jets on their propulsive characteristics have been investigated numerically for different dimensionless distances $S/D$ (the distance between two jet axes normalised by nozzle diameter, from 1.1 to 4) and stroke ratios $L/D$ (the length-to-diameter ratio of jet column, from 2 to 5). The two jets are arranged in parallel and initiated simultaneously with identical conditions. Their leading vortical structures evolve from an axisymmetric to a plane-symmetric configuration, with deceleration in regions where the two jet wakes approach each other. The generation of axial thrust is affected, primarily dominated by variations in the pressure thrust component. This results from the combination of the mutually induced pressure (MIP) and the coupling effects of vortex rings (CEVR for $S/D\gt1.5$ and CEVR-R for $S/D\lt1.5$). The MIP governs the fluctuations introduced into thrust development, while CEVR (CEVR-R) is responsible for the reduction in average thrust. These effects become more pronounced as $S/D$ decreases, but remain almost unaffected by $L/D$. Adjusting the acceleration and deceleration rates of the velocity program shows limited effects on either the thrust fluctuations or the average thrust reduction. Furthermore, the interaction induces two lateral force components with equal magnitude but opposite directions on the outer walls of the two nozzles, with their magnitude exceeding $15\,\%$ of the axial thrust. The introduction of an additional vertical wall within the nozzle exit plane effectively eliminates the lateral force. However, it consequently enhances both the average thrust reduction and the thrust fluctuations induced by the interaction.
This paper presents an experimental and analytical investigation of the turbulent transport and flame geometric characteristics of free turbulent buoyant diffusion flames under different fuel mass fluxes and burner boundary conditions (i.e. with/without a flush floor). The stereo particle image velocimetry technique was utilised to measure the three-dimensional instantaneous velocity fields of the free methane buoyant flames with a burner diameter (d) of 0.30 m and dimensionless heat release rates ($\dot{Q}^{*}$) of 0.50–0.90. The results showed that, compared with the configuration without a floor, the time-averaged axial velocity fluctuations squared and the time-averaged radial velocity fluctuations squared decreased, and the peak values of the time-averaged radial velocity, the time-averaged radial velocity fluctuations squared and the time-averaged axial and radial fluctuation product shifted towards the burner centreline in the configuration with a flush floor. Based on the dimensional analysis and the gradient transport assumption, the mean turbulent viscosity within the mean flame height ($\nu _{t}^{=}$) was scaled. Compared with the configuration without a floor of under equal $\dot{Q}^{*}$, the turbulent viscosity decreased in the configuration with a flush floor, resulting in an increase in mean flame height and a reduction in mean flame width. Based on the concepts of turbulent mixing and equal axial convection and radial diffusion times, semi-physical models were derived for the mean flame height and the mean flame width, respectively. The two correlations agreed well with the experimental data of this work for the two burner configurations with and without a flush floor.
Directional freezing of brine is widely found in numerous environmental and industrial settings. Despite extensive studies, the microscopic evolution of ice-brine structures remains unclear. By combining in situ micro-computed tomography visualisation and theoretical analyses, we reveal new details inside the porous ice structure and its evolution towards a cleaner ice layer. We identify three distinct stages characterised by different brine exclusion rates during solidification: a rapid initial stage possibly lasting seconds from nucleation to local equilibrium without long-range heat or mass transfer; a second stage where the system reaches global thermal equilibrium, involving brine expulsion by volume expansion and convection associated with gravity; and a final prolonged stage dominated by diffusion. Comparison between analytical solutions and the migration rates of microstructural features such as brine stripes, columns and pockets extracted from photographic images confirms these understandings. Morphologically, we capture the formation of random striped patterns together with brine columns during downward freezing and brine skirts during upward freezing, all of which gradually transform into vertically aligned polygonal patterns. The volume fraction of brine pockets in porous ice near the cold end reduces to less than 10 % after 22 h in most experiments. The residual brine pockets, however, are not rejected out of the porous ice as fast as predicted by diffusion and remain persistent. Our findings provide new insights into the brine freezing dynamics, with implications ranging from sea ice formation to freeze desalination and general solidification of binary melts.
The formation process of a vortex pair generated by a two-dimensional starting jet has been investigated numerically over a range of Reynolds numbers from 500 to 2000. The effects of stroke ratio and nozzle configuration are examined. Only a single vortex pair can be observed in the vorticity field generated by small stroke ratios less than 10 while the leading vortex pair formed by larger stroke ratios eventually disconnects from the trailing jet. The formation numbers (13.6 and 9.3) for a straight nozzle and an orifice nozzle have been identified by the circulation criterion and they are further analysed by four other criteria. Using the contraction coefficient, formation numbers can be transformed into a universal value at about 16.5 for both nozzles. The effect of Reynolds number on the formation number is found to be within 12 % for parallel flow cases but it will increase up to 27 % for non-parallel flow cases due to shear-layer instability. A modified contraction-based slug model is proposed, and it can accurately predict the total invariants (e.g. circulation, hydrodynamic impulse and kinetic energy) shedding from the nozzle edge. Analytical estimation of the formation number is further conducted by matching the predicted total invariants to the Pierrehumbert model of steady vortex pairs. By assuming that pinch-off starts when the vortex pair achieves the steady state, two analytical models are proposed in terms of vortex impulse and translational velocity. The latter appears to be more appropriate to predict the formation number for two-dimensional flows.
The formation mechanism for the stopping vortex ring (SVR) and its effects on the development of starting jets have been systematically investigated. The radial inward flow near the nozzle exit, arising from the pressure difference caused by the deceleration of starting jets, is considered to be the main contributing factor to the formation of the SVR. The formation process can generally be divided into (i) the rapid accumulation stage ($t_d^*\leq 1$) and (ii) the development stage ($t_d^*>1$), where $t_d^*$ is the formation time defined by the duration of the deceleration stage. For starting jets with different $(L/D)_d$, the final circulation value and circulation growth rate of the SVR can be scaled by $[(L/D)_d]^{-0.5}$ and $[(L/D)_d]^{-1.5}$, respectively. Here $(L/D)_d$ represents the stroke ratio during the deceleration stage. Analysing the temporal evolution of fluid parcels in the vicinity of the nozzle exit reveals that SVR entrains fluid from both inside and outside of the nozzle. Additionally, the influence of the SVR on the leading vortex ring and the trailing jet has been examined, with particular attention to its effects on the propulsive performance of the starting jet. The SVR affects the profiles of axial velocity and gauge pressure at the nozzle exit, thereby enhancing the generation of total thrust during the deceleration stage. Analysis has shown that depending on the deceleration rate, SVR can enhance the average velocity thrust by at least $10\,\%$ and compensate for up to a $60\,\%$ reduction in pressure thrust due to deceleration.
Foodborne diseases are ongoing and significant public health concerns. This study analysed data obtained from the Foodborne Outbreaks Surveillance System of Wenzhou to comprehensively summarise the characteristics of foodborne outbreaks from 2012 to 2022. A total of 198 outbreaks were reported, resulting in 2,216 cases, 208 hospitalisations, and eight deaths over 11 years. The findings suggested that foodborne outbreaks were more prevalent in the third quarter, with most cases occurring in households (30.8%). Outbreaks were primarily associated with aquatic products (17.7%) as sources of contamination. The primary transmission pathways were accidental ingestion (20.2%) and multi-pathway transmission (12.1%). Microbiological aetiologies (46.0%), including Vibrio parahaemolyticus, Salmonella ssp., and Staphylococcus aureus, were identified as the main causes of foodborne outbreaks. Furthermore, mushroom toxins (75.0%), poisonous animals (12.5%), and poisonous plants (12.5%) were responsible for deaths from accidental ingestion. This study identified crucial settings and aetiologies that require the attention of both individuals and governments, thereby enabling the development of effective preventive measures to mitigate foodborne outbreaks, particularly in coastal cities.
The AIMTB rapid test assay is an emerging test, which adopted a fluorescence immunochromatographic assay to measure interferon-γ (IFN-γ) production following stimulation of effector memory T cells in whole blood by mycobacterial proteins. The aim of this article was to explore the ability of AIMTB rapid test assay in detecting Mycobacterium tuberculosis (MTB) infection compared with the widely applied QuantiFERON-TB Gold Plus (QFT-Plus) test among rural doctors in China. In total, 511 participants were included in the survey. The concordance between the QFT-Plus test and the AIMTB rapid test assay was 94.47% with a Cohen’s kappa coefficient (κ) of 0.84 (95% CI, 0.79–0.90). Improved concordance between the two tests was observed in males and in participants with 26 or more years of service as rural doctors. The quantitative values of the QFT-Plus test was higher in individuals with a result of QFT-Plus-/AIMTB+ as compared to those with a result of QFT-Plus-/AIMTB- (p < 0.001). Overall, our study found that there was an excellent consistency between the AIMTB rapid test assay and the QFT-Plus test in a Chinese population. As the AIMTB rapid test assay is fast and easy to operate, it has the potential to improve latent tuberculosis infection testing and treatment at the community level in resource-limited settings.
This study assesses the difference in professional attitudes among medical students, both before and after coronavirus disease 2019 (COVID-19), and identifies the determinants closely associated with it, while providing precise and scientific evidence for implementing precision education on such professional attitudes.
Methods:
A pre-post-like study was conducted among medical students in 31 provinces in mainland China, from March 23, to April 19, 2021.
Results:
The proportion of medical students whose professional attitudes were disturbed after the COVID-19 pandemic, was significantly lower than before the COVID-19 pandemic (χ2 = 15.6216; P < 0.0001). Compared with the “undisturbed -undisturbed” group, the “undisturbed-disturbed” group showed that there was a 1.664-fold risk of professional attitudes disturbed as grade increased, 3.269-fold risk when others suggested they choose a medical career rather than their own desire, and 7.557-fold risk for students with COVID-19 in their family, relatives, or friends; while the “disturbed-undisturbed” group showed that students with internship experience for professional attitudes strengthened was 2.933-fold than those without internship experience.
Conclusions:
The professional attitudes of medical students have been strengthened during the COVID-19 pandemic. The results provide evidence of the importance of education on professional attitudes among medical students during public health emergencies.
Product graphics interchange formats (GIFs) employ this format to show the features of the product and make up for the lack of physical experience online. These GIFs have been widely applied in domains such as e-shopping and social media, aiming to interest and impress viewers. Contrary to this wide application, most designers in this domain lack expertise and produce GIFs of varied quality. Moreover, the knowledge of techniques to enhance viewers’ engagement with product GIFs is also lacking. To bridge the gap, we conducted a series of studies. First, we collected and summarized seven design factors referring to existing literature and semi-structured interviews. Then, the impacts of these design factors were revealed through an online study with 106 product GIFs among 307 participants. The results showed that visual-related factors such as color contrast and moving intensity mainly impact viewers’ interest, while content-related factors such as scenario and style matching impact viewers’ impressions. The simplicity of GIFs also impressed viewers with a quick viewing mode. Finally, we conducted a workshop and verified that these results support large-scale production of product GIFs. Our studies might support the codesign methods of product GIFs and enhance their quality in design practice.
Our previous studies have suggested that spastin, which aggregates on spindle microtubules in oocytes, may promote the assembly of mouse oocyte spindles by cutting microtubules. This action may be related to CRMP5, as knocking down CRMP5 results in reduced spindle microtubule density and maturation defects in oocytes. In this study, we found that, after knocking down CRMP5 in oocytes, spastin distribution shifted from the spindle to the spindle poles and errors in microtubule–kinetochore attachment appeared in oocyte spindles. However, CRMP5 did not interact with the other two microtubule-severing proteins, katanin-like-1 (KATNAL1) and fidgetin-like-1 (FIGNL1), which aggregate at the spindle poles. We speculate that, in oocytes, due to the reduction of spastin distribution on chromosomes after knocking down CRMP5, microtubule–kinetochore errors cannot be corrected through severing, resulting in meiotic division abnormalities and maturation defects in oocytes. This finding provides new insights into the regulatory mechanisms of spastin in oocytes and important opportunities for the study of meiotic division mechanisms.
This study investigates whether the management earnings forecasts of Republican and Democratic CEOs differ due to systematic differences in their information disclosure preferences. We find that Republican CEOs prefer a less asymmetric information environment than Democrat CEOs, and thus make more frequent, timelier, and more accurate disclosures than Democrat CEOs. Results using the propensity score matched sample and difference-in-differences analysis show that our results are unlikely to be driven by potential endogeneity. Our results are robust to controlling for various CEO characteristics and are stronger for firms with higher levels of institutional ownership and litigation risk.
The formation process of the leading vortex ring in starting jets with uniform background co- and counter-flow has been studied numerically for $-0.5\leq R_v\leq 0.5$, where $R_v$ is the ratio of background velocity to jet velocity. For the cases with background counter-flow, the normal formation process of the leading vortex ring would be destroyed when $R_v<-0.4$, i.e. the trailing jet would overtake the leading vortex ring through the centre, a phenomenon reminiscent of vortex leapfrogging. As the velocity ratio $R_v$ increases, the formation number $F_{t^*}$ decreases from $9.6$ at $R_v=-0.4$ to $1.92$ at $R_v=0.5$. An analytical model based on the kinematic criterion has been developed so as to describe the relationship between the formation number $F_{t^*}$ and velocity ratio $R_v$. A linear relationship between the vortex core parameter and stroke ratio of starting jet ($\varepsilon \sim k_1L/D$) for the Norbury vortex ring has been established and used effectively to close the model. For co-flow with $0< R_v\leq 0.5$, the results from this model are consistent with the present numerical simulation and the experiments by Krueger et al. (J. Fluid Mech., vol. 556, 2006, pp. 147–166). For counter-flow, two different equations are proposed for $-0.4\leq R_v\leq -0.2$ and $-0.2< R_v<0$, respectively.
It is very challenging for robots to perform grinding and polishing tasks on surfaces with unknown geometry. Most existing methods solve this problem by modeling the relationship between the force sensing information and surface normal vectors by analyzing the forces on special end tools such as spherical tools and cylindrical tools and simplified friction model. In this paper, we propose a normal vectors learning method to simultaneously control end-effector force and direction on unknown surfaces. First, the relation that mapping the force sensing information to the surface normal vectors is learned from the demonstrated data on the known plane using locally weighted regression. Next, the learned relation is used to estimate surface normal vectors on the unknown surface. To improve the force control precision on the unknown geometry surface, the adaptive force control is developed. To improve the direction control precision due to friction, the iterative learning control is developed. The proposed method is verified by comparative simulations and experiments using the Franka robot. Results show that the end-effector can be controlled perpendicular to the surface with a certain force.
We test the signaling view of corporate social responsibility (CSR) engagement using two complementary quasi-natural experiments that impose exogenous negative pressure on stock prices. Firms under such adverse price pressure increase CSR activities compared to otherwise similar firms. This effect concentrates among firms with stronger signaling incentives, namely, those facing greater information asymmetry, more product market competition, higher shareholder litigation risk, and higher stock price crash risk. Firms under the exogenous negative price pressure mainly improve CSR strengths, including costly environmental investments. We also find that CSR engagement attracts socially responsible investors and lowers the cost of capital for signaling firms.
The grey wolf optimizer (GWO) as a new intelligent optimization algorithm has been successfully applied in many fields because of its simple structure, few adjustment parameters and easy implementation. This paper mainly aims at the defects of GWO in path planning application, such as easily falling into local optimization, poor convergence and poor accuracy, and turn point grey wolf optimization (TPGWO) algorithm is proposed. First, the idea of cross-mutation and roulette is used to increase the initial population of GWO and improve the search range. At the same time, the convergence factor function is improved to become a nonlinear update. In the early stage, the search range is expanded, and in the later stage, the convergence speed is increased, while the parameters in the convergence factor function can be adjusted according to the number of obstacles and the map area to change the turning point of the function to improve the convergence speed and accuracy of the algorithm. The turning times and turning angles of the obtained path are added to the fitness function as penalty values to improve the path accuracy. The optimization test is carried out through 16 test functions, and the test results prove the convergence and robustness of TPGWO algorithm. Finally, the TPGWO algorithm is applied to the path planning of patrol robot for simulation experiments. Compared with the GWO algorithm and Particle Swarm Optimization, the simulation results show that the TPGWO algorithm has better convergence, stability and accuracy in the path planning of patrol robot.
A dual-band dual-linearly polarized waveguide slot array antenna is proposed in this paper. Two orthogonal slots share a short-circuit wall on broad side. The horizontal and vertical slots, which actualize dual-frequency bands and dual-linear polarization, generate vertically polarized electric fields in 9.39–9.78 GHz and horizontally polarized electric fields in 11.62–12.3 GHz, respectively. The equivalent permittivity of the waveguide is changed by two grooves at the bottom of the waveguide, which improves phase velocity. Two grooves can also reduce the distance between the elements while suppressing the side lobes. Compared to filling the medium in the waveguide, two grooves have less losses. Moreover, the antenna is simple with one input port. The array antenna also overcomes the problems of beam scanning compared with the traditional waveguide slot array antenna. A 1 × 8 antenna array is fabricated and measured to verify the design. The horizontal polarization is formed in 9.39–9.78 GHz, the vertical polarization is generated in 11.62–12.3 GHz, and the antenna gain can reach 15 dBi.
The low maturation rate of oocytes is an important reason for female infertility and failure of assisted pregnancy. The germinal vesicle breakdown (GVBD) is a landmark event of oocyte maturation. In our previous studies, we found that zona pellucida 3 (ZP3) was strongly concentrated in the nuclear region of germinal vesicle (GV) oocytes and interacted with aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) and lamin A to promote GVBD. In the current study, we found that lamin A is mainly concentrated in the nuclear membrane. When ZP3 is knocked down, lamin A will be partially transferred to the nucleus of oocytes. The prelamin A is increased in both the nuclear membrane and nucleus, while phosphorylated lamin A (p-lamin A) is significantly reduced. AIPL1 was also proved to accumulate in the GV region of oocytes, and ZP3 deletion can significantly inhibit the aggregation of AIPL1 in the nuclear region. Similar to ZP3 knockdown, the absence of AIPL1 resulted in a decrease in the occurrence of GVBD, an increase in the amount of prelamin A, and a significant decrease in p-lamin A in oocytes developed in vitro. Finally, we propose the hypothesis that ZP3 can stabilize farnesylated prelamin A on the nuclear membrane of AIPL1, and promote its further processing into mature lamin A, therefore promoting the occurrence of GVBD. This study may be an important supplement for the mechanism of oocyte meiotic resumption and provide new diagnostic targets and treatment clues for infertility patients with oocyte maturation disorder.
The formation and evolution process of the outer vortex ring (denoted as OV0) in annular starting jets has been studied numerically at stroke ratio $3\leqslant L_m/D\leqslant 8$, $\beta \leqslant 0.8$ and Reynolds number $400\leqslant Re_{\triangle R}\leqslant 1400$, where $D$ is the outer diameter of orifice, $L_m$ is the length of the fluid column, $\beta$ and $\triangle R$ are the ratio and difference between inner and outer radii of the annular orifice, respectively. The initial formation process of OV0 is found to be similar to that of the leading vortex ring in a circular starting jet, but the circulation strength is relatively lower and decreases gradually with increasing $\beta$. The pinch-off process will also appear after OV0 grows to a certain size but is different from that of the circular starting jet. On one hand, OV0 is stretched and deformed by the strain field generated by the trailing jet's instability, and vorticity would be shed. On the other hand, OV0 accelerates the irrotational fluids around it under viscous action so as to form the induced velocity field, which would consume energy causing it to shed vorticity further under the limit of the Kelvin–Benjamin variational principle. Furthermore, OV0 would eventually become a stable vortex ring whose non-dimensional circulation ($\varGamma /(U_{0max}D$)) is found to be between 0.59–0.62 and it would not change with different $L_m/D$ at $\beta =0.5$, which is much less than the 2–2.5 of circular starting jets.