Product architecture decisions are made early in the product development process and have far-reaching effects. Unless anticipated through experience or intuition, many of these effects may not be apparent until much later in the development process, making changes to the architecture costly in time, effort and resources. Many researchers through the years have studied various elements of product architecture and their effects. By using a repeatable process for aggregating statements on the effects of architecture strategies from a selection of the literature on the topic and storing them in a systematic database, this information can then be recalled and presented in the form of a Product Architecture Strategy and Effect (PASE) matrix. PASE matrices allow for the identification, comparison, evaluation, and then selection of the most desirable product architecture strategies before expending resources along a specific development path. This paper introduces the PASE Database and matrix and describes their construction and use in guiding design decisions. This paper also provides metrics for understanding the robustness of this database.

Late Postclassic lowland Maya civic-ceremonial masonry architecture appears in two main configurations—temple assemblages and basic ceremonial groups—first identified at Mayapan. Around the Peten lakes, these two architectural complexes have been tied to northern immigrant Kowojs and Itzas, respectively, and their distributions map the varying control over the lakes by these two ethnopolities. Temple assemblages exhibit considerable variation in their structural components and arrangements throughout the lowlands, but they have not been studied comparatively. Here, we examine 14 temple assemblages at 12 lowland sites. We consider one of the two assemblages at Zacpeten (Sak Peten), Group A, to have been built by Kowojs, who asserted their identity and earlier (Late/Terminal Classic) ties to the site by reusing carved monuments. “Blended” assemblage Group C is more difficult to parse, but reflects cosmo-calendrical principles of statecraft and the builders’ and users’ broader ties to Mayapan and Topoxte.

Suicide is a leading cause of death in the United States, particularly among adolescents. In recent years, suicidal ideation, attempts, and fatalities have increased. Systems maps can effectively represent complex issues such as suicide, thus providing decision-support tools for policymakers to identify and evaluate interventions. While network science has served to examine systems maps in fields such as obesity, there is limited research at the intersection of suicidology and network science. In this paper, we apply network science to a large causal map of adverse childhood experiences (ACEs) and suicide to address this gap. The National Center for Injury Prevention and Control (NCIPC) within the Centers for Disease Control and Prevention recently created a causal map that encapsulates ACEs and adolescent suicide in 361 concept nodes and 946 directed relationships. In this study, we examine this map and three similar models through three related questions: (Q1) how do existing network-based models of suicide differ in terms of node- and network-level characteristics? (Q2) Using the NCIPC model as a unifying framework, how do current suicide intervention strategies align with prevailing theories of suicide? (Q3) How can the use of network science on the NCIPC model guide suicide interventions?

The emergence and dissemination of new legal ideas can play an important role in sparking change in the way activists in marginalized communities understand their rights and pursue their objectives. How and why do the legal beliefs of such communities evolve? We argue that the vigorous advocacy of new legal ideas by entrepreneurs and the harnessing of specialized media to help disseminate those ideas are important mechanisms in this evolution. We use the rise of marriage equality as a central legal priority in the mainstream American LGBTQ+ rights movement as a case study to illustrate this phenomenon. Using a mixed-methods analysis of Evan Wolfson’s legal advocacy and an examination of The Advocate, we investigate how Wolfson developed and disseminated legal ideas about same-sex marriage. We show how this advocacy eventually dominated discussion of the issue among elite LGBTQ+ legal actors and the nation’s largest LGBTQ+ publication. However, Wolfson’s advocacy tended to emphasize LGBTQ+ integration into “mainstream” American culture and prioritized the interests and values of relatively privileged subgroups within the LGBTQ+ community. Our research informs our understanding of the interplay between legal advocacy and media reporting in the development of LGBTQ+ rights claims and the strategies adopted to achieve them.

In an attempt to resolve the structure of opal-CT and opal-C more precisely, 24 opal samples from bentonites, Fuller's Earths, zeolite tuffs, biogenic silicas and silicified kaolins have been analyzed by high resolution transmission electron microscopy (HRTEM) and X-ray diffraction (XRD). Results of this examination demonstrate that opal-C and opal-CT are part of a continuous series of intergrowths between end-member cristobalite and tridymite stacking sequences.

These findings are consistent with Flörke's (1955) interpretation of the most intense opal peak at ~4 Å as a combination of the (101) cristobalite and (404) tridymite peaks. The position and width of this peak are controlled by the relative volume of the two stacking types and the mean crystallite size. Direct evidence obtained by HRTEM provides data showing various stacking sequences in opals. Broadening due to crystallite size alone was determined by directly measuring crystallite size by TEM and comparing the measured size to the apparent size calculated using the Scherrer equation. XRD peak broadening is also described in terms of various contributions from structural disorder. The mean opal crystallite size ranges from 120 to 320 Å. For samples at either end of the size range, the crystallite size plays a larger role, relative to stacking disorder, in controlling peak broadening.

Scholars have long questioned whether and how courts influence society. We contribute to this debate by investigating the ability of judicial decisions to shape issue attention and affect toward courts in media serving the LGBTQ+ community. To do so, we compiled an original database of LGBTQ+ magazine coverage of court cases over an extended period covering major decisions, including Lawrence v. Texas (2003), Goodridge v. Massachusetts Department of Public Health (2003), and Lofton v. Secretary of Department of Children & Family Services (2004). We argue these cases influence the volume and tone of LGBTQ+ media coverage. Combining computational social science techniques with qualitative analysis, we find increased attention to same-sex marriage after the decisions in Lawrence, Goodridge, and Lofton, and the coalescence of discussions of courts around same-sex marriage after Lawrence. We also show how LGBTQ+ media informed readers about the political and legal implications of struggles over marriage equality.

Patients diagnosed with attention-deficit hyperactivity disorder (ADHD) are at an elevated risk for suicide. No prior work has assessed the association between stimulant prescriptions and death by suicide in this population. This retrospective cohort study included Department of Veterans Affairs patients with an active ADHD diagnosis that received stimulant medications between 2016 and 2019. We found that months with active stimulant medication prescription was associated with decreased risk of suicide mortality compared with months without stimulant medication (odds ratio 0.57, 95% CI 0.36–0.88). Our results suggest that prescribing stimulant medications for patients diagnosed with ADHD is associated with decreased risk of suicide mortality.

This paper explores the processes of specialized viticulture in the province of Gallia Narbonensis over the first three centuries CE and brings this evidence to bear on broader economic questions, particularly as they relate to the effects of connectivity and globalization on Roman economic development. Evidence from small farms to sprawling villas suggests that specialized production stretched across multiple strata of society in Narbonensis, from so-called peasants to the wealthiest elites. The existence of specialized agricultural production at the scale documented in Narbonensis required significant demand, well-connected and integrated markets, sustained trade, and an awareness of these economic factors by the residents of the province. The evidence presented here demonstrates that the residents of Narbonensis recognized that they were part of an economic environment in which high levels of connectivity and integrated markets allowed them to pursue more profitable production strategies and that they pursued these opportunities.

I propose a “Milky Way / creation hypothesis” for the elongated eastern structures in early Maya E Groups: they were modeled on the Milky Way galaxy. These architectural arrangements, beginning in the Preclassic period (c. 900 B.C.–A.D. 200) in the southern Maya Lowlands, were adopted from predecessors in the Early Preclassic neighboring Gulf Coast region. The widespread overall similarity of E Groups suggests a shared belief system centered on myths about creation, and many of the characters (e.g., Maize God) and events of creation in Maya myths are set in the Milky Way. The general north–south axial orientation of the eastern platform, frequently pivoted northeast–southwest, is proposed to be related to the rainy season position of the Milky Way overhead. E Groups were probably multifunctional ritual theaters, the eastern platforms serving as stages for nighttime performances of creation stories. Late modifications into a tripart edifice, with structures or superstructures in the center and at both ends, replicated the major asterisms of the visible galaxy and/or the creator gods.

There are accumulating international data in a number of livestock industries that show that a negative attitude by stockpeople towards interacting with pigs, dairy cattle and poultry is correlated with increased levels of fear and stress in farm animals and in turn reduced animal productivity. While most of this research has been on-farm, one study has shown similar attitude-behaviour correlations in a pig abattoir. The major aim of this research was to examine the stockperson attitude-behaviour at sheep and cattle abattoirs. Twenty-two Australian abattoirs participated in the collection of stockperson attitudes and behaviour (81 stockpeople — 35 cattle stockpeople and 46 sheep stockpeople; six abattoirs slaughtering cattle, six slaughtering sheep and ten slaughtering both cattle and sheep). Several significant correlations between stockperson attitudes and behaviour were detected. In particular, the perceived pressures imposed by perceived lack of control over their actions, perceived time constraints, perceived effect of poor facilities and inappropriate beliefs about arousing livestock were all associated with frequent use of forceful handling behaviours by the stockperson. These results were similar to observations in pig abattoirs that have been reported previously. These relationships at cattle and sheep abattoirs indicate that there may be an opportunity to improve stockperson behaviour and consequently reduce stress in sheep and cattle at abattoirs by targeting attitudes (and behaviour) for improvement, with appropriate educational and training material in a way that is similar to the uses of such training with livestock species in farm settings.

Racially and ethnically minoritized populations have been historically excluded and underrepresented in research. This paper will describe best practices in multicultural and multilingual awareness-raising strategies used by the Recruitment Innovation Center to increase minoritized enrollment into clinical trials. The Passive Immunity Trial for Our Nation will be used as a primary example to highlight real-world application of these methods to raise awareness, engage community partners, and recruit diverse study participants.

Nixtun-Ch'ich', on the western edge of Lake Peten Itza in Peten, northern Guatemala, features an axis urbis and an urban grid dating to the Middle Preclassic period (800–500 b.c.). New research reveals that Middle Preclassic constructions—five circular or oval artificial pools and planned surface drainage—facilitated or impeded the movement of water. Large limestone rubble lines at least two of the pools (aguadas) in the city's core; two pools lie on the axis urbis, demonstrating that they were central ceremonial constructions. The gridded streets facilitated drainage: they consistently slope from west to east and from the center to north and south. In some areas seeing intense water flow, the streets divide into waterways and pedestrian-ways and/or were given special paving. Many scholars argue that water management contributed to the power of despotic kings, but no evidence of such rulers exists among the Middle Preclassic Maya. Nonetheless, we believe that such systems emerged in the Middle Preclassic. Nixtun-Ch'ich' appears to have been cooperative in its organization and its water management system was a public good.

In 1977 concern for the long-range effects of policy-making prompted President Carter to direct the U.S. Council on Environmental Quality and the Department of State to study the “probable changes in the world's population, natural resources, and environment through the end of the century.” The projections of that commission, as detailed in The Global 2000 Report to the President (Barney et al. 1981), foresee a growth in the world's population of as much as 70 percent, combined with staggering increases in demand for the world's resources of water, minerals, soils, and forest products.

Mental health (MH) apps can be used as adjunctive tools in traditional face-to-face therapy to help implement components of evidence-based treatments. However, practitioners interested in using MH apps face a variety of challenges, including knowing which apps would be appropriate to use. Although some resources are available to help practitioners identify apps, granular analyses of how faithfully specific clinical skills are represented in apps are lacking. This study aimed to conduct a review and analysis of MH apps containing a core component of cognitive behaviour therapy (CBT) – cognitive restructuring (CR). A keyword search for apps providing CR functionality on the Apple App and Android Google Play stores yielded 246 apps after removal of duplicates, which was further reduced to 15 apps following verification of a CR component and application of other inclusionary/exclusionary criteria. Apps were coded based on their inclusion of core elements of CR, and general app features including app content, interoperability/data sharing, professional involvement, ethics, and data safeguards. They were also rated on user experience as assessed by the Mobile App Rating Scale (MARS). Whereas a majority of the CR apps include most core CR elements, they vary considerably with respect to more granular sub-elements of CR (e.g. rating the intensity of emotions), other general app features, and user experience (average MARS = 3.53, range from 2.30 to 4.58). Specific apps that fared best with respect to CR fidelity and user experience dimensions are highlighted, and implications of findings for clinicians, researchers and app developers are discussed.

The spectrum of adverse mental health trajectories caused by sexual abuse, broadly defined as exposure to rape and unwanted physical sexual contact, is well-known. Few studies have systematically appraised the epidemiology and impact of sexual abuse among boys and men. New meta-analytic insights (k = 44; n = 45 172) reported by Zarchev and colleagues challenge assumptions that men experiencing mental ill health rarely report sexual abuse exposure. Adult-onset sexual abuse rates of 1–7% are observed in the general population, but for men experiencing mental ill health, adult lifetime prevalence was 14.1% (95% CI 7.3–22.4%), with past-year exposure 5.3% (95% CI 1.6–12.8%). We note that these rates are certainly underestimates, as childhood sexual abuse exposures were excluded. Boys and men with a sexual abuse history experience substantial disclosure and treatment barriers. We draw attention to population health gains that could be achieved via implementation of gender-sensitive assessment and intervention approaches for this at-risk population.