Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

18 results

  • Chapter 9 - A Neuroimaging Network-Level Approach to Drug-Resistant Epilepsy

  • Edited by Rod C. Scott, University of Vermont, J. Matthew Mahoney, University of Vermont
  • Book:
    A Complex Systems Approach to Epilepsy
    Published online:
    06 January 2023
    Print publication:
    26 January 2023, pp 127-134

  • Summary

    Epilepsy affects approximately 1% of the population [1]. Although generally treatable, up to 30% of patients do not achieve seizure freedom from anticonvulsive medication alone. Due to its relationship with cognitive abilities [2], quality of life [3], and the associated risk of premature death [4], drug-refractory epilepsy should be treated promptly. Temporal lobe epilepsy (TLE) associated with mesiotemporal sclerosis [5] and extra-temporal lobe epilepsy related to focal cortical dysplasia (FCD) [6] constitute the most common refractory epilepsy syndromes. Surgical resection of these lesions remains the treatment of choice [7], with success rates approaching 80% [8]. By allowing the detection of epileptogenic lesions and offering system-level mechanisms of the disease process, MRI has shifted the field from electro-clinical correlations toward a multidisciplinary approach.

Imaging Biomarkers in Epilepsy
  • Edited by Andrea Bernasconi, Neda Bernasconi, Matthias Koepp
  • Published online:
    07 January 2019
    Print publication:
    10 January 2019
  • Epilepsy is a prevalent and serious neurological disorder. This vital textbook addresses the role of neuroimaging as a unique tool to provide in vivo biomarkers aimed at furthering our understanding of causes and consequences of epilepsy in a day-to-day clinical context. Unique in its approach, this translational book presents a critical appraisal of advanced pre-clinical biomarkers that allows capturing epileptogenesis at molecular, cellular, and neuronal system levels. The book is divided into four sections. Part I includes a series of chapters focused on imaging of early disease stages. Part II discusses lesion detection and network analysis methods. Part III focuses on imaging methods used to predict response to antiepileptic drugs and surgery. Finally, Part IV presents imaging techniques used to evaluate disease consequence.