We analyze household inventories from eight excavated residences at El Palmillo (Oaxaca, Mexico) with a focus on a large sample of spindle whorls. Measurement of the whorls provides a basis to suggest that a variety of fibers were spun in these Classic period households; however, the particular mix of fibers varied in each residence. The distribution of whorls by size and production technique was compared with the spatial patterning of other tool classes related to cloth production to illustrate that each household participated with differing intensity in the various steps of the cloth-making process while also being involved in other economic pursuits. The domestic multicrafting, along with the clear procurement of domestic goods through intra- and extracommunity transfers, is indicative of economic practices that incorporate both interdependence and flexibility to operate in a socioeconomic setting prone to fluctuations in both demand and climatic conditions such as those found in the Valley of Oaxaca, Mexico. The model generated from this bottom-up analysis illustrates the limitation of the command-oriented models of the prehispanic Mesoamerican economy and sheds new light on craft specialization and economic strategies that vary not only between elite and nonelite families but among commoner households as well.