The purpose of this article is to describe a series of recent studies from the authors and many of their colleagues aimed at improving the food environments of adolescents in the Netherlands and thereby improving their food choices. These studies are performed in the wider context of national and local strategies for the prevention of overweight and obesity in the Netherlands. Interventions were developed with local stakeholders and carried out in schools, supermarkets and low-income neighbourhoods. We conclude that current national policies in the Netherlands are largely ineffective in reducing the prevalence of overweight and obesity. Local integrated programmes in the Netherlands, however, seem to result in a reduction of overweight, especially in low-income neighbourhoods. It is impossible to say which elements of such an integrated approach are effective elements on their own. We found very little evidence for the effectiveness of separate interventions aimed at small changes in the food environment. This suggests that such interventions are only effective in combination with each other and in a wider systems approach. Future studies are needed to further develop the practical methodology of implementation and evaluation of systems science in combination with participatory action research.

The analysis of the geographical distribution of hospital cases is obviously important for the purpose of planning hospital services, but it is of even greater significance in the planning of psychiatric services. This concern motivated our seven-year-long study, which examined hospitalization risks among various categories of psychiatric disorders in the major German city of Hamburg. Our database encompassed 77% (n = 64,000) of all psychiatric admissions in a total of 41 hospitals, most of which are general hospitals. In order to carry out the geographical analysis we employed a new statistical method based on a mixture distribution model. According to our findings, the strongest indications of an increased frequency were among male cases of schizophrenia, drug abuse and organic psychoses, and female cases of neurotic disorders, personality disorders, drug abuse and schizophrenia. We found that some areas are exposed to a risk of hospitalization for these diagnostic categories which is more than 50% above the reference. Contrary to other authors we did not identify an increased frequency of admission concentrated in the inner-city area for any of the diagnostic groups. The risk of hospitalization for schizophrenics was almost entirely associated with the close proximity of psychiatric units, while the risks for neuroses and personality disorders, as well as alcohol and drug abuse, appeared to be concentrated in areas of low social status. However, a statistically relevant correlation between an increased risk of hospitalization and low social status could be determined only for drug abuse and alcoholism. In the end, we did identify two areas in which there was an increased risk of hospitalization for several diagnostic groups, and this information will undoubtedly facilitate the planning of hospital and psychiatric services. The fact that our findings deviate to some extent from other authors – especially with respect to neuroses and personality disorders, but also to addiction – can be attributed to the inclusion of psychiatric cases from general hospitals in our geographic analysis.

We introduce the Galaxy IFU Spectroscopy Tool (GIST), a convenient, all-in-one and multi-purpose tool for the analysis and visualisation of already reduced (integral-field) spectroscopic data. In particular, the pipeline performs all steps from read-in and preparation of data to its scientific analysis and visualisation in publication-quality plots. The code measures stellar kinematics and non-parametric star formation histories using the pPXF routine (Cappellari & Emsellem 2004; Cappellari 2017), performs an emission-line analysis with the GandALF procedure (Sarzi et al. 2006; Falcón-Barroso et al. 2006), and determines absorption line-strength indices and their corresponding single stellar population equivalent population properties (Kuntschner et al.2006; Martín-Navarro et al. 2018). The dedicated visualisation routine Mapviewer facilitates the access of all data products in a sophisticated graphical user interface with fully interactive plots.

We study the stellar content of three galactic bulges with the high resolution gratings (R=7000) of the WiFeS integral field unit in order to better understand their formation and evolution. In all cases we find that at least 50% of the stellar mass already existed 12 Gyrs ago, more than currently predicted by simulations. A younger component (age between ∼1 to ∼8 Gyrs) is also prominent and its present day distribution seems to be much more affected by morphological structures, especially bars, than the older one. This in-depth analysis supports the notion of increasing complexity in bulges which cannot be achieved by mergers alone, but requires a non-negligible contribution from secular evolution.

The ability to perform the instrumental activities of daily living (IADLs) is an important focus for the promotion of independent living in old age. If strategies to enable older people to remain in their own homes are to be developed, advances must be made in understanding the demands associated with IADLs. This paper reports on a study of how activity demands – the body postures, actions and hand functions involved in cooking, housework, laundering and shopping – relate to the capabilities of a sample of older people in Great Britain. Task data were analysed for 4,886 community-dwelling 55–93-year-olds who were enrolled in a follow-up survey to the 1996/97 Family Resources Survey. Logistic regression models were used to calculate adjusted odds ratios for associations between functional limitations and IADL difficulty. Attributable fraction estimates were also used to assess the population impact of the functional limitations. Comparable effect sizes were observed across activities for limitations in body postures (standing, reaching and bending/stooping), actions (lifting/lowering and holding/carrying) and hand functions. Most of the difficulties were attributable to limitations in body postures, primarily bending/stooping, whereas actions and hand functions accounted for much less difficulty. We present a matrix of the potential impact that design changes to alleviate each limitation would have on the ability to perform the activities studied. This can help to prioritise interventions aimed at supporting continued independent living.

The development of high power ion diodes for inertial confinement fusion is in progress on the PBFA I accelerator. The three main types of magnetically-insulated ion diodes, the Applied-B, Hybrid, and Pinch Reflex diodes, are compared. This paper presents the results from the first series of tests of the Hybrid diode.

Fully electromagnetic, relativistic, two-dimensional, particle-in-cell (PIC) simulations of barrel-type and extractor-type Applied-B ion diodes have increased our confidence in the design of present and future diodes for the Particle Beam Fusion Accelerator II (PBFA II). In addition, the data from various experiments on Pro to I, Proto II, and PBFA I Applied-B ion diodes are inconsistent with previous models of diode operation, based on anode-cathode gap closure from expanding plasmas. A new model has been devised and applied to the PBFA II diode to explain the diode impedance and its time history, and to suggest methods for controlling the impedance.

The CRESST-II direct Dark Matter search is located in the Gran Sasso underground laboratories, Italy. CaWO4 crystals are used as scintillating targets for WIMP (weakly interacting massive particle) interactions. They are operated as cryogenic calorimeters in combination with a second cryogenic detector used to measure the scintillation light produced in the target crystal. For each particle interaction, the combination of phonon and light signals provides an event by event discrimination which allows to distinguish known particles (alphas, betas, gammas, neutrons) from the expected signal of WIMPs. A major upgrade of the setup comprises modifications of the shielding, installation of a muon-veto, and new read out electronics, as well as a new detector-support structure to accommodate up to 33 detector modules, i.e. 10 kg of target mass. The experiment was thereafter successfully commissioned in 2007. Data obtained during this commissioning phase from 2 detector modules are presented here. Combining the data collected with these two detector modules with data from one single module obtained during the CRESST-I phase, the experiment could already place a limit of ~6 × 10-7 pb for the spin independent WIMP-nucleon scattering cross section at a WIMP mass of ~60 GeV/c2.

EURECA (European Underground Rare Event Calorimeter Array) is an astro-particle physics facility aiming to directly detect galactic dark matter. The Laboratoire Souterrain de Modane has been selected as host laboratory. The EURECA collaboration unites CRESST, EDELWEISS and the Spanish-French experiment ROSEBUD, thus concentrating and focussing effort on cryogenic detector research in Europe into a single facility. EURECA will use a target mass of up to one ton, enough to explore WIMP – nucleon scalar scattering cross sections in the region of 10-9 – 10-10 picobarn. A major advantage of EURECA is the planned use of more than just one target material (multi target experiment for WIMP identification).

CVC plus® is a worldwide established and well proventechnology package to control profile and flatness in hot stripmills and plate mills. Latest developments of this technologyare the application of CVC plus® grindings on work and backuprolls, CVC plus® grindings of higher order and intelligentshifting strategies. The capability of the developments isdemonstrated with recent operational results.

Mechanical Q-factor measurements of single crystalline calcium fluoride CaF2 bulk material are presented. Resonant modes between 27 and 100 kHz were investigated on a cylindrical test sample ( $\varnothing$ $75~{\rm mm} \times 75~{\rm mm}$ ). For selected modes low temperature measurements of the mechanical Q-factor were done within a temperature range from 5 to 300 K. For the Q-measurements a ring-down technique was used. The substrate was suspended as a pendulum by means of a tungsten wire loop. The highest Q-factor has been achieved around 60 K with 3 × 108 which is the highest Q-factor reported on CaF2 up to now.

Summary

Background and objectives: Salt-water aspiration results in pulmonary oedema and hypoxia. We tested the hypothesis that partial liquid ventilation has beneficial effects on gas exchange and rate of survival in acute and extended salt water-induced lung injury. Methods: Anaesthetized, ventilated rats (tidal volume 6 mL kg−1, PEEP 5 cmH2O) received a tracheal salt-water instillation (3%, 8 mL kg−1 body weight) and were randomly assigned to three groups (n = 10 per group). While lungs of Group 1 were gas-ventilated, lungs of Group 2 received a single perfluorocarbon instillation (30 min after the injury, 5 mL kg−1 perfluorocarbon) and lungs of Group 3 received an additional continuous perfluorocarbon application into the treachea (5 mL kg−1 h−1). Arterial blood gases were measured with an intravascular blood gas sensor. Results: Salt-water instillation resulted in a marked decrease in PaO2 values within 30 min (from 432 ± 65 to 83 ± 40 mmHg, FiO2 = 1.0, P < 0.01). Arterial oxygenation improved in all three groups irrespective of treatment. We observed no significant differences between groups in peak PaO2 and PaCO2 values. Conclusions: Our results suggest that partial liquid ventilation has no additional beneficial effects on gas exchange after life-threatening salt water-induced lung injury when compared to conventional gas ventilation with positive end-expiratory pressure.

El análisis de la distribución geográfica de los casos hospitalarios es obviamente importante con miras a planificar los servicios hospitalarios, pero tiene una significación incluso mayor en la planificación de los servicios psiquiátricos. Esta preocupación motivó nuestro estudio de siete años, que examinó los riesgos de hospitalización entre diversas categorías de trastornos psiquiátricos en la importante ciudad alemana de Hamburgo. Nuestra base de datos abarcaba el 77% (n = 64.000) de todas las admisiones psiquiátricas en un total de 41 hospitales, la mayoría de los cuales son hospitales generales. Para llevar a cabo el análisis geográfico empleamos un método estadístico nuevo basado en un modelo de distribución mixto. Según nuestros resultados, las indicaciones más poderosas de una frecuencia mayor estaban entre los casos masculinos de esquizofrenia, abuso de drogas y psicosis orgánicas, y los casos femeninos de trastornos neuróticos, trastornos de la personalidad, abuso de drogas y esquizofrenia. Encontramos que algunas áreas están expuestas a un riesgo de hospitalización para estas categorías diagnósticas que está más del 50% por encima de la referencia. Contrariamente a otros autores, no identificamos una frecuencia mayor de admisión concentrada en el área céntrica de la ciudad para cualquiera de los grupos diagnósticos. El riesgo de hospitalización para los esquizofrénicos se asociaba casi por entero con la estrecha proximidad de las unidades psiquiátricas, mientras que los riesgos para las neurosis y los trastornos de la personalidad, así como para el abuso de alcohol y de drogas, parecían concentrarse en áreas de posición social baja. Sin embargo, sólo se pudo determinar una correlación estadísticamente pertinente entre un mayor riesgo de hospitalización y posición social baja para el abuso de drogas y el alcoholismo. Al final, identificamos dos áreas en las que había un riesgo mayor de hospitalización para varios grupos diagnósticos, y esta información facilitará sin duda la planificación de los servicios hospitalarios y psiquiátricos. El hecho de que nuestros resultados se desvíen hasta cierto punto de los de otros autores especialmente con respecto a las neurosis y los trastornos de la personalidad, pero también para la adicción- se puede atribuir a la inclusión de casos psiquiátricos de los hospitales generales en nuestro análisis geográfico.

High quality single-crystal CoSi2 layers have been successfully formed on Si(100) using low energy high dose Co ion implantation followed by subsequent annealing method as a buffer layer for the deposition of YBa2Cu3O7−x (YBCO) thin films. Rutherford backscattering spectrometry with channeling (RBS-C) measurements showed that CoSi2 layers after annealing at temperatures between 850 and 950 °C had a minimum yield Xmin of about 3%. X-ray diffraction (XRD) spectra revealed that CoSi2 layers had the same orientation as the Si(100) substrates. Phi scan XRD spectra proved that CoSi2 layers epitaxially grew in the cube-on-cube epitaxial growth mode with respect to the Si(100) substrates. YBCO films and CeO2/YSZ buffer layers were deposited on CoSi2/Si(100) substrates via laser ablation and electron beam evaporation, respectively. θ-2θ, ω, and φ scan XRD spectra illustrated that YBCO films and CeO2/YSZ buffer layers had the epitaxial structure both in a-b plane and along the c-axis. YBCO films grown on this multilayered structure demonstrated excellent superconducting properties with the zero resistance transition temperature Tc0 of 87–90 K. The transition width (ΔTc) was about 1 K. Orientation and epitaxial crystalline quality of YBCO films and CeO2/YSZ buffer layers were confirmed by XRD and RBS-C characterization. All films consisted of c-axis oriented grains. RBS-C spectra indicated a high degree of crystalline perfection with a channeling minimum yield for Ba as low as 8%, and interdiffusion between the YBCO film and buffer layers or between the YBCO film and the substrate was limited. This multilayer system shows the possibility for the application of YBa2Cu3O7−x thin films on technical Si substrates in the field of hybrid superconductor-semiconductor technology.

In high performance integrated circuits, low dielectric constant (low-ε) materials are required as inter-level dielectric (ILD) for on-chip interconnect to provide advantages in high speed, low dynamic power dissipation and low cross-talk noise. A variety of low dielectric constant materials, which include fluorinated silicon-oxide, porous silica and porous organic materials, chemical vapor deposited and spin-on deposited (SOD) organic materials, have been developed or are under development to fulfill this need. In this paper, we first review the need and integration architecture of low-ε materials for on-chip interconnect. Then, we discuss the consequence of using low-ε materials as ILD in advanced interconnect with emphasis on the ILD electrical characteristics and the interconnect reliability. Although the focus is on several new promising SOD low-ε materials, the developed evaluation methodology is applicable to other type low-ε materials as well.