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Engineering machines are becoming increasingly complex and possess more control variables, increasing the complexity and versatility of the control systems. Different configurations of the control system, named a policy, can result in similar output behavior but with different resource or component life usage. There is therefore an opportunity to find optimal policies with respect to economic decisions. While many solutions have been proposed to find such economic policy decisions at the asset level, we consider this problem at the fleet level. In this case, the optimal operation of each asset is affected by the state of all other assets in the fleet. Challenges introduced by considering multiple assets include the construction of economic multi-objective optimization criteria, handling rare events such as failures, application of fleet-level constraints, and scalability. The proposed solution presents a framework for economic fleet optimization. The framework is demonstrated for economic criteria relating to resource usage, component lifing, and maintenance scheduling, but is generically extensible. Direct optimization of lifetime distributions is considered in order to avoid the computational burden of discrete event simulation of rare events. Results are provided for a real-world case study targeting the optimal economic operation of a fleet of aerospace gas turbine engines.
Based on the best-selling Stahl's Prescriber's Guide, this essential guide to psychiatric prescribing has been developed by leading psychiatrists and medical students from the University of Cambridge to support all mental health professionals in achieving optimal care for their patients. Written with the authority of evidence and the guidance of clinical wisdom the formulary covers the psychotropic medications used in daily care including dosing recommendations and drug interactions. With its easy-to-use, full-colour template-driven navigation system, the book combines evidence-based data with clinically informed advice, including guidance on prescribing for children and adolescents and people with addictions. Drugs are presented in the same format to facilitate rapid access to information and are broken down into sections designated by a unique colour background thereby clearly distinguishing information presented on therapeutics, side effects, dosing and use, and the art of psychopharmacology. Popular prescribing 'tips and pearls are included throughout.
Radiocarbon data are the most commonly used chronometric measurement technique in archaeology. The introduction of the radiocarbon method offered new potential for independent, internationalized research projects. Today millions of radiocarbon measurements exist globally. However, the many strengths of radiocarbon for research in archaeology have also created an internationally significant challenge in heritage practice. How can we attempt to curate huge volumes of radiocarbon “legacy” data in systematic ways that facilitate interdisciplinary, international research? How can we contend with a dataset that is rapidly scalable, and needs to be kept live—updated, validated, curated, and related to existing national archives and data systems—beyond the timescale of any individual project? In this paper we introduce an international project, “Project Radiocarbon; Big Data, integrated cross-national heritage histories”, working across the historic environment sector in Ireland and the United Kingdom, that is developing a solution to these issues. We argue that we need to think critically about how we classify and curate radiocarbon data, to render them interoperable and findable. Such work requires inter-sector approaches to ensure sustainability and scalability, and to anticipate the increasing value of these data into the future.
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust
Edited by
Sepehr Hafizi, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,Peter B. Jones, University of Cambridge,Stephen M. Stahl, University of California, San Diego
Edited in association with
Veronika Dobler, Cambridgeshire and Peterborough NHS Foundation Trust,Liliana Galindo, Cambridgeshire and Peterborough NHS Foundation Trust and University of Cambridge,George Griffiths, Cambridgeshire and Peterborough NHS Foundation Trust,Neil Hunt, University of Cambridge,Mohammad Malkera, University of Cambridge,Asha Praseedom, Cambridgeshire and Peterborough NHS Foundation Trust,Pranathi Ramachandra, Cambridgeshire and Peterborough NHS Foundation Trust,Judy Rubinsztein, University of Cambridge,Shamim Ruhi, Norfolk and Suffolk NHS Foundation Trust