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Ultra-processed foods (UPF), defined using the Nova classification system, are associated with increased chronic disease risk. More recently, evidence suggests the UPF subgroup of whole-grain breads and cereals is in fact linked with reduced chronic disease risk. This study aimed to explore associations of cardiometabolic risk measures with Nova UPF intake v. when foods with ≥ 25 or ≥ 50 % whole grains are excluded from the definition. We considered dietary data from the Australian National Nutrition and Physical Activity Survey 2011–2012. Impacts on associations of UPF intake (quintiles) and cardiometabolic risk measures were analysed using regression models. The median proportion of UPF intake from high whole-grain foods was zero for all quintiles. Participants in the highest Nova UPF intake quintile had significantly higher weight (78·1 kg (0·6)), BMI (27·2 kg/m2 (0·2)), waist circumference (92·7 cm (0·5)) and weight-to-height ratio (0·55 (0·003)) compared with the lowest quintile (P< 0·05). Associations were the same when foods with ≥ 25 and ≥ 50 % whole grains were excluded. Adjusted R-squared values remained similar across all approaches for all outcomes. In Australia, high whole-grain foods considered UPF may not significantly contribute to deleterious cardiometabolic risk associations. Until conclusive evidence on Nova UPF is available, prioritisation should be given to the nutrient density of high whole-grain foods and their potential contribution to improving whole-grain intakes and healthful dietary patterns in Australia.
We present observations of the Mopra carbon monoxide (CO) survey of the Southern Galactic Plane, covering Galactic longitudes spanning $l = 250^{\circ}$ ($-110^{\circ}$) to $l = 355^{\circ}$ ($-5^{\circ}$), with a latitudinal coverage of at least $|b|<1^\circ$, totalling an area of $>$210 deg$^{2}$. These data have been taken at 0.6 arcmin spatial resolution and 0.1 km s$^{-1}$ spectral resolution, providing an unprecedented view of the molecular gas clouds of the Southern Galactic Plane in the 109–115 GHz $J = 1-0$ transitions of $^{12}$CO, $^{13}$CO, C$^{18}$O, and C$^{17}$O.
Despite becoming increasingly represented in academic departments, women scholars face a critical lack of support as they navigate demands pertaining to pregnancy, motherhood, and child caregiving. In addition, cultural norms surrounding how faculty and academic leaders discuss and talk about tenure, promotion, and career success have created pressure for women who wish to grow their family and care for their children, leading to questions about whether it is possible for these women to have a family and an academic career. This paper is a call to action for academia to build structures that support professors who are women as they navigate the complexities of pregnancy, the postpartum period, and the caregiving demands of their children. We specifically call on those of us in I-O psychology, management, and related departments to lead the way. In making this call, we first present the realistic, moral, and financial cases for why this issue needs to be at the forefront of discussions surrounding success in the academy. We then discuss how, in the U.S. and elsewhere, an absence of policies supporting women places two groups of academics—department heads (as the leaders of departments who have discretion outside of formal policies to make work better for women) and other faculty members (as potential allies both in the department and within our professional organizations)—in a critical position to enact support and change. We conclude with our boldest call—to make a cultural shift that shatters the assumption that having a family is not compatible with academic success. Combined, we seek to launch a discussion that leads directly to necessary and overdue changes in how women scholars are supported in academia.
Livestock welfare assessment helps monitor animal health status to maintain productivity, identify injuries and stress, and avoid deterioration. It has also become an important marketing strategy since it increases consumer pressure for a more humane transformation in animal treatment. Common visual welfare practices by professionals and veterinarians may be subjective and cost-prohibitive, requiring trained personnel. Recent advances in remote sensing, computer vision, and artificial intelligence (AI) have helped developing new and emerging technologies for livestock biometrics to extract key physiological parameters associated with animal welfare. This review discusses the livestock farming digital transformation by describing (i) biometric techniques for health and welfare assessment, (ii) livestock identification for traceability and (iii) machine and deep learning application in livestock to address complex problems. This review also includes a critical assessment of these topics and research done so far, proposing future steps for the deployment of AI models in commercial farms. Most studies focused on model development without applications or deployment for the industry. Furthermore, reported biometric methods, accuracy, and machine learning approaches presented some inconsistencies that hinder validation. Therefore, it is required to develop more efficient, non-contact and reliable methods based on AI to assess livestock health, welfare, and productivity.
To describe pathogen distribution and rates for central-line–associated bloodstream infections (CLABSIs) from different acute-care locations during 2011–2017 to inform prevention efforts.
Methods:
CLABSI data from the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) were analyzed. Percentages and pooled mean incidence density rates were calculated for a variety of pathogens and stratified by acute-care location groups (adult intensive care units [ICUs], pediatric ICUs [PICUs], adult wards, pediatric wards, and oncology wards).
Results:
From 2011 to 2017, 136,264 CLABSIs were reported to the NHSN by adult and pediatric acute-care locations; adult ICUs and wards reported the most CLABSIs: 59,461 (44%) and 40,763 (30%), respectively. In 2017, the most common pathogens were Candida spp/yeast in adult ICUs (27%) and Enterobacteriaceae in adult wards, pediatric wards, oncology wards, and PICUs (23%–31%). Most pathogen-specific CLABSI rates decreased over time, excepting Candida spp/yeast in adult ICUs and Enterobacteriaceae in oncology wards, which increased, and Staphylococcus aureus rates in pediatric locations, which did not change.
Conclusions:
The pathogens associated with CLABSIs differ across acute-care location groups. Learning how pathogen-targeted prevention efforts could augment current prevention strategies, such as strategies aimed at preventing Candida spp/yeast and Enterobacteriaceae CLABSIs, might further reduce national rates.
The Planck all-sky submillimetre observations have made it possible to study Galactic cold clumps in diverse environments, to probe dust properties and to examine the earliest stages of star formation. The TOP-SCOPE joint survey program aims to statistically study the evolution of molecular clouds and the initial conditions of star formation in a wide variety of environments. In this work we carry out an investigation of the 200 brightest compact sources detected by Planck.
In an earlier study on the variations in micro-structure during large volumetric deformations of snow, the authors observed that, contrary to expectations, the length of necked regions connecting adjacent grains did not necessarily decrease during compression. Rather, there was no discernible or predictable change in neck length, in some cases increasing and in others decreasing. Further evaluations of the data and an analysis of the mechanics of neck deformation determined that the process is complicated by three different effects: (1) increase in coordination number (number of bonds per grain), (ii) plastic deformation of the neck, and (iii) a geometric effect determined by bond growth and grain geometry. It is found that the first two effects tend to decrease the neck length and that the third produces an increase in mean neck length. A set of coupled differential equations is developed describing the variation of neck length and bond radius, and solved numerically for conditions consistent with the experimental data. Calculated results agree well with the data for the bond radius but the results for the neck length are less satisfactory. Reasons for this lie with difficulty in making accurate measurements of mean neck length from two-dimensional surface-section data and in the criteria for the definition of necks.
Epilepsy is a common medical condition for which physicians perform driver fitness assessments. The Canadian Medical association (CMA) and the Canadian Council of Motor transportation administrators (CCMTA) publish documents to guide Canadian physicians’ driver fitness assessments.
Objectives:
We aimed to measure the consistency of driver fitness counseling among epileptologists in Canada, and to determine whether inconsistencies between national guidelines are associated with greater variability in counseling instructions.
Methods:
We surveyed 35 epileptologists in Canada (response rate 71%) using a questionnaire that explored physicians’ philosophies about driver fitness assessments and counseling practices of seizure patients in common clinical scenarios. Of the nine scenarios, CCMTA and CMA recommendations were concordant for only two. Cumulative agreement for all scenarios was calculated using Kappa statistic. Agreement for concordant (two) vs. discordant (seven) scenarios were split at the median and analyzed using the Wilcoxon signed rank sum test.
Results:
Overall the agreement between respondents for the clinical scenarios was not acceptable (Kappa=0.28). For the two scenarios where CMa and CCMta guidelines were concordant, specialists had high levels of agreement with recommendations (89% each). A majority of specialists disagreed with CMa recommendations in three of seven discordant scenarios. The lack of consistency in respondents’ agreement attained statistical significance (p<0.001).
Conclusions:
Canadian epileptologists have variable counseling practices about driving, and this may be attributable to inconsistencies between CMa and CCMta medical fitness guidelines. This study highlights the need to harmonize driving recommendations in order to prevent physician and patient confusion about driving fitness in Canada.
Inflammation is a stereotypical physiological response to infections and tissue injury; it initiates pathogen killing as well as tissue repair processes and helps to restore homeostasis at infected or damaged sites. Acute inflammatory reactions are usually self-limiting and resolve rapidly, due to the involvement of negative feedback mechanisms. Thus, regulated inflammatory responses are essential to remain healthy and maintain homeostasis. However, inflammatory responses that fail to regulate themselves can become chronic and contribute to the perpetuation and progression of disease. Characteristics typical of chronic inflammatory responses underlying the pathophysiology of several disorders include loss of barrier function, responsiveness to a normally benign stimulus, infiltration of inflammatory cells into compartments where they are not normally found in such high numbers, and overproduction of oxidants, cytokines, chemokines, eicosanoids and matrix metalloproteinases. The levels of these mediators amplify the inflammatory response, are destructive and contribute to the clinical symptoms. Various dietary components including long chain ω-3 fatty acids, antioxidant vitamins, plant flavonoids, prebiotics and probiotics have the potential to modulate predisposition to chronic inflammatory conditions and may have a role in their therapy. These components act through a variety of mechanisms including decreasing inflammatory mediator production through effects on cell signaling and gene expression (ω-3 fatty acids, vitamin E, plant flavonoids), reducing the production of damaging oxidants (vitamin E and other antioxidants), and promoting gut barrier function and anti-inflammatory responses (prebiotics and probiotics). However, in general really strong evidence of benefit to human health through anti-inflammatory actions is lacking for most of these dietary components. Thus, further studies addressing efficacy in humans linked to studies providing greater understanding of the mechanisms of action involved are required.
Kaolinite-mudstone bands, widely recoginzed in the Carboniferous of Western Europe, where they are known as tonsteins, are also represented in Britain. On the basis of the probable correlation eight such bands have so far been found in the Coal Measures of the East Midlands. Laterally two of these bands are thought to pass into rocks intermediate in type between tonstein and more normal Coal Measures mudstones.
Feeding trials with sheep, subsisting out-of-doors on typical winter rations of known dry-matter and starch-equivalent content, have been carried out during the winters of 1933–4, 1934–5 and 1935–6. Records have been kept over these periods of the live-weights of the animals and their daily consumption of dry matter and starch equivalent.
It has been found that the standards of appetite, in terms of lb. dry matter, proposed by Prof. T. B. Wood are uniformly too high, a result in harmony with the findings of Prof. J. A. S. Watson and co-workers at Oxford. It is suggested that Prof. Wood's values should be multiplied throughout by the factor 0·85 in order to obtain reasonable measures of the appetites of sheep at different live-weights.
The data from the feeding trials have been used in an attempt to decide between the old and the recently proposed standards for the maintenance starch-equivalent requirement of the 100 lb. sheep, namely, 0·74 and 1·26 lb. of starch equivalent per day. The results point to the reliability of the higher figure, and it is shown that the results of recent work on the energy metabolism of sheep are in harmony with this conclusion.
A table embodying a revision of Prof. Wood's feeding standards for sheep is included in the paper.
A technique for measuring the appetites of sheep on pasture is described.
Results are given to show that sheep consume a bigger ration, in terms of lb. dry matter, when on pasture than when subsisting out-of-doors on the winter type of diet composed of hay, swedes (or kale) and concentrates. This difference was noted even on grass that had deteriorated in quality, in one case as a result of hot, dry weather in early summer, and in a second case as a consequence of cold, dry weather in spring. With young, leafy pasturage at its best, however, the distinction is most marked.
In the March of 1934, to quote but one example, four pure-bred Suffolk wethers, of live-weight varying from 120 to 181 lb., were shown to consume, on a diet of concentrates (350 g. daily), swedes (ad lib.) and chaffed hay (ad lib.), only 80–88 per cent of the amounts of dry matter predicted on the basis of Wood's feeding standards. During the following May, when grazing leafy pasturage of very good quality (digestion coefficient of organic matter = 81·l per cent), the appetites of the same sheep (range of live-weight now from 137 to 201 lb.) were found to have undergone a striking stimulation, the mean daily consumption of dry matter now being from 104 to 117 per cent of the amounts predicted from the standards. This implied that the sheep were consuming 1·13, 1·37, 1·13 and T53 lb. respectively more dry matter per day than they would have eaten had the diet consisted of hay, concentrates and swedes. The increased appetite is to be attributed to the superior palatability of the young grass.
The paper records the results of an investigation into the composition, digestibility and nutritive value of marrow stem kale (both unthinned and singled-out) and thousand head kale. A number of the main findings are recorded below.
The average dry-matter content of unthinned marrow stem kale during September and October was 13·3 per cent. During the following January it had reached a slightly higher level, namely, 14·2 per cent. Singling out of the marrow stem kale appeared to exercise little effect on the dry-matter content of the crop. Thousand head kale, with an average dry-matter content of 15·8 per cent., is significantly richer in dry matter than the marrow stem kale, although this advantage was offset by the lower yield, in terms of green matter, given per acre by the thousand head kale.
The development is recorded of the series of experiments with potatoes at Rothamsted during 1925–27, designed to examine the quantitative response of yield to varying quantities of nitrogenous and potassic manures, and to test the relative value with this crop of different sources of potash.
While rather precise comparisons were obtained on the qualitative question by means of Latin squares in 1925–26, the reality of the depression ascribable to chloride could not be demonstrated in these years, but became clearly apparent when in the following year, the qualitative experiment was merged with the quantitative one.
In the earlier quantitative experiments, although satisfactory responses were obtained, the precision of the results left much to be desired, since only four replicates could be used. When by merging the experiments this was increased to nine replicates, much smaller responses were clearly measurable.
The large and complex type of experiment finally adopted thus supplied more precise information on both heads than could previously be obtained, and in addition to a more thorough exploration of the different combinations possible.
The practice of applying nitrogenous fertilisers to cereal crops as a top dressing is one which has become firmly incorporated into normal farm routine.
The classic wheat experiment on Broadbalk field shows that to apply all the nitrogenous fertiliser at the time of drilling the seed in autumn leads to a diminution in crop when compared with the yield of a plot in which only a quarter of the nitrogenous fertiliser was applied in autumn.
We present the adaptive optics assisted, near-infrared VLTI instrument GRAVITY for precision narrow-angle astrometry and interferometric phase referenced imaging of faint objects. With its two fibers per telescope beam, its internal wavefront sensors and fringe tracker, and a novel metrology concept, GRAVITY will not only push the sensitivity far beyond what is offered today, but will also advance the astrometric accuracy for UTs to 10 μas. GRAVITY is designed to work with four telescopes, thus providing phase referenced imaging and astrometry for 6 baselines simultaneously. Its unique capabilities and sensitivity will open a new window for the observation of a wide range of objects, and — amongst others — will allow the study of motion within a few times the event horizon size of the Galactic Center black hole.