Field and laboratory studies were conducted to evaluate the efficacy of several herbicides applied after small-grain harvest on Russian thistle (Salsola iberica Sennen and Pau # SASKR) control and subsequent seed germination. Best postharvest control of Russian thistle was with chlorsulfuron {2-chloro-N-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino] carbonyl] benzenesulfonamide} treatments, paraquat (1,1′-dimethyl-4,4′-bipyridinium ion), and bromoxynil (3,5-dibromo-4-hydroxybenzonitrile) plus metribuzin [4-amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one], where control ranged from 73 to 96%. During the summer-fallow year, chlorsulfuron and paraquat decreased Russian thistle population and biomass compared to the untreated control. Germination of large seeds from plants treated with paraquat and both rates of chlorsulfuron was reduced at least 64% compared to seeds of similar size from untreated plants.