Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

154 results

Page 1 of 8

  • 49 Case Study: Cognitive Deficits Associated with Norrie Disease

  • Amy LeRoy, Khushnoo K Indorewalla, Richard Phenis, Joyce Yi Hsuan Ku
  • Journal:
    Journal of the International Neuropsychological Society / Volume 29 / Issue s1 / November 2023
    Published online by Cambridge University Press:
    21 December 2023, pp. 655-656
    • Article
      • You have access
    • PDF
    • Export citation
  • Objective:

    Norrie disease is a rare, x-linked recessive genetic disorder associated with an NDP gene mutation. Males are predominantly affected. Typical symptoms include vision loss around the time of birth and progressive hearing loss. Cognitive and behavioral abnormalities also occur in 30-50% of individuals, including developmental delays, intellectual disability, cognitive regression, psychosis, and aggression. There is limited research, however, examining the neuropsychological deficits in adulthood resulting from Norrie disease, especially with neuropsychological data and in individuals without other neurological manifestations of the disease, such as seizures. Here, we present the neurocognitive profile of a patient with Norrie disease who presented for a cognitive evaluation in adulthood due to report of more recent memory decline.

    Participants and Methods:

    Mr. Smith is a Caucasian male in his mid-40's who previously underwent genetic testing and was subsequently diagnosed with Norrie disease. As a result of his diagnosis, he experienced complete vision loss since birth and bilateral hearing loss that began in childhood and gradually worsened in adolescence. Medical history was otherwise unremarkable. Developmental milestones were met on time. Historical intelligence testing conducted in elementary school revealed borderline on one intelligence test to high average performance on other intelligence tests. However, he was retained grades several times due to factors such as behavioral disruptions and academic difficulties. He had been employed as an assembly line worker for many years, but had not worked for 10 years prior to the neuropsychological evaluation. Emotionally, he had a longstanding history of anxiety and endorsed mild anxiety and depression at the time of the evaluation. The patient first noticed memory difficulties in adolescence then noticed further decline four years prior to the neuropsychological evaluation (around when he received a left-ear cochlear implant), which had remained stable since onset.

    Results:

    In the context of low average premorbid intellectual functioning, Mr. Smith's neurocognitive profile was notable for difficulties with alphanumeric set-shifting and abstract thinking, with otherwise preserved cognitive functioning. Weaknesses observed on testing may have represented longstanding weaknesses and did not rise to the level of a cognitive disorder. Affective distress was also suspected to have accounted for some of the cognitive lapses the patient reported experiencing with day-to-day functioning.

    Conclusions:

    The current poster aims to contribute to the limited body of literature examining neuropsychological deficits in adulthood resulting from Norrie disease. This is especially critical given that the long-term cognitive dysfunction of this disorder is relatively unknown and could negatively impact patients' quality of life over time.

  • 8 - Managing Responsibly

  • from Part III - Relationship-Building Skills for Global Managers
  • Richard M. Steers, University of Oregon, Joyce S. Osland, San José State University, California, Betina Szkudlarek, University of Sydney
  • Book:
    Management Across Cultures
    Published online:
    07 September 2023
    Print publication:
    21 September 2023, pp 236-271

  • Summary

    This chapter explores the following issues: key ethical and social challenges facing both companies and managers; the nature of ethical and institutional conflicts; hallmarks of ethical managerial behavior; laws and conventions on ethical behavior; and corporate environment-social-government initiatives aimed at giving back to global communities

  • 7 - Communicating Across Cultures

  • from Part III - Relationship-Building Skills for Global Managers
  • Richard M. Steers, University of Oregon, Joyce S. Osland, San José State University, California, Betina Szkudlarek, University of Sydney
  • Book:
    Management Across Cultures
    Published online:
    07 September 2023
    Print publication:
    21 September 2023, pp 204-235

  • Summary

    This chapter explores several aspects of intercultural communication, including the following: a model of the intercultural communication process; the influence of culture, combined with communication practices, on interpersonal behavior; barriers to effective intercultural communication; direct and indirect communication in intercultural interactions; understanding and recognizing different communication styles; and providing culturally-sensitive feedback to colleagues and co-workers

  • 6 - Leading People and Organizations

  • from Part III - Relationship-Building Skills for Global Managers
  • Richard M. Steers, University of Oregon, Joyce S. Osland, San José State University, California, Betina Szkudlarek, University of Sydney
  • Book:
    Management Across Cultures
    Published online:
    07 September 2023
    Print publication:
    21 September 2023, pp 165-203

  • Summary

    This chapter explores topics related to key questions about leadership in global settings, including: the meaning of leadership; how Eastern and Western leadership traditions differ; the meaning of global leadership; a look at two leadership models; the role of gender in leader behavior and success; and evaluating global leadership outcomes and effectiveness

  • 11 - Working and Living Globally

  • from Part III - Relationship-Building Skills for Global Managers
  • Richard M. Steers, University of Oregon, Joyce S. Osland, San José State University, California, Betina Szkudlarek, University of Sydney
  • Book:
    Management Across Cultures
    Published online:
    07 September 2023
    Print publication:
    21 September 2023, pp 341-376

  • Summary

    This chapter explores what is involved in global assignments, from moving abroad to returning home. Topics include: the purposes and types of global assignments; potential benefits and challenges of living and working globally; dealing with culture shock; choosing an acculturation strategy; and successful repatriation

  • 3 - Cultural Environments

  • from Part II - Contextual Skills for Global Managers
  • Richard M. Steers, University of Oregon, Joyce S. Osland, San José State University, California, Betina Szkudlarek, University of Sydney
  • Book:
    Management Across Cultures
    Published online:
    07 September 2023
    Print publication:
    21 September 2023, pp 51-87

  • Summary

    This chapter explores cultural environments, including a look at the nature and characteristics of cultures and subcultures; several contemporary models of national cultures; recent refinements to the models and how they can help managers understand some of the nuances of cultural differences; how managers can use these models to better understand managerial and organizational behavior; and the challenges and opportunities of cultural diversity and multiculturalism.

  • 5 - Managerial Work Environments

  • from Part II - Contextual Skills for Global Managers
  • Richard M. Steers, University of Oregon, Joyce S. Osland, San José State University, California, Betina Szkudlarek, University of Sydney
  • Book:
    Management Across Cultures
    Published online:
    07 September 2023
    Print publication:
    21 September 2023, pp 127-162

  • Summary

    This chapter examines several aspects of work and management, including the following: a look at what constitutes the global work environment for managers; how people’s expectations about suitable managerial behavior can differ; how situational differences can influence managerial behavior; how beliefs about work and leisure can vary across cultures; what motivates people at work in different situations and environments; and multiculturalism and inclusivity in the global workplace

  • 10 - Managing Global Teams

  • from Part III - Relationship-Building Skills for Global Managers
  • Richard M. Steers, University of Oregon, Joyce S. Osland, San José State University, California, Betina Szkudlarek, University of Sydney
  • Book:
    Management Across Cultures
    Published online:
    07 September 2023
    Print publication:
    21 September 2023, pp 308-340

  • Summary

    This chapter examines the following topics: key challenges facing the organization and management of global teams; managing teams and team processes; creating global team synergy; special management challenges of dispersed global teams; and leadership and global team-building

Page 1 of 8