The Magellanic Stream (MS), a tail of diffuse gas formed from tidal and ram pressure interactions between the Small and Large Magellanic Clouds (SMC and LMC) and the Halo of the Milky Way, is primarily composed of neutral atomic hydrogen (HI). The deficiency of dust and the diffuse nature of the present gas make molecular formation rare and difficult, but if present, could lead to regions potentially suitable for star formation, thereby allowing us to probe conditions of star formation similar to those at high redshifts. We search for $\text{HCO}^{+}$, HCN, HNC, and C$_2$H using the highest sensitivity observations of molecular absorption data from the Atacama Large Millimeter Array (ALMA) to trace these regions, comparing with HI archival data from the Galactic Arecibo L-Band Feed Array (GALFA) HI Survey and the Galactic All Sky Survey (GASS) to compare these environments in the MS to the HI column density threshold for molecular formation in the Milky Way. We also compare the line of sight locations with confirmed locations of stars, molecular hydrogen, and OI detections, though at higher sensitivities than the observations presented here.

We find no detections to a 3$\sigma$ significance, despite four sightlines having column densities surpassing the threshold for molecular formation in the diffuse regions of the Milky Way. Here we present our calculations for the upper limits of the column densities of each of these molecular absorption lines, ranging from $3 \times 10^{10}$ to $1 \times 10^{13}$ cm$^{-2}$. The non-detection of $\text{HCO}^{+}$ suggests that at least one of the following is true: (i) $X_{\text{HCO}^{+}{}, \mathrm{MS}}$ is significantly lower than the Milky Way value; (ii) that the widespread diffuse molecular gas observed by Rybarczyk (2022b, ApJ, 928, 79) in the Milky Way’s diffuse interstellar medium (ISM) does not have a direct analogue in the MS; (iii) the HI-to-$\text{H}_{2}$ transition occurs in the MS at a higher surface density in the MS than in the LMC or SMC; or (iv) molecular gas exists in the MS, but only in small, dense clumps.

Childhood obesity represents a significant global health concern and identifying its risk factors is crucial for developing intervention programs. Many “omics” factors associated with the risk of developing obesity have been identified, including genomic, microbiomic, and epigenomic factors. Here, using a sample of 48 infants, we investigated how the methylation profiles in cord blood and placenta at birth were associated with weight outcomes (specifically, conditional weight gain, body mass index, and weight-for-length ratio) at age six months. We characterized genome-wide DNA methylation profiles using the Illumina Infinium MethylationEpic chip, and incorporated information on child and maternal health, and various environmental factors into the analysis. We used regression analysis to identify genes with methylation profiles most predictive of infant weight outcomes, finding a total of 23 relevant genes in cord blood and 10 in placenta. Notably, in cord blood, the methylation profiles of three genes (PLIN4, UBE2F, and PPP1R16B) were associated with all three weight outcomes, which are also associated with weight outcomes in an independent cohort suggesting a strong relationship with weight trajectories in the first six months after birth. Additionally, we developed a Methylation Risk Score (MRS) that could be used to identify children most at risk for developing childhood obesity. While many of the genes identified by our analysis have been associated with weight-related traits (e.g., glucose metabolism, BMI, or hip-to-waist ratio) in previous genome-wide association and variant studies, our analysis implicated several others, whose involvement in the obesity phenotype should be evaluated in future functional investigations.

In 1969 R.T.É.'s 7 Days dealt with the issue of illegal moneylending, claiming that Dublin was ‘a city of fear’ where 500 unlicensed moneylenders used violence as a tool to collect debts. The Fianna Fáil government rejected the suggestion that loan sharking was widespread and that Gardaí responses to it were ineffectual; a tribunal of inquiry was established to investigate 7 Days. Previous analyses situated these events within the context of government concerns over the influence of television journalism. This article takes a different approach, analysing moneylending ― rather than 7 Days ― within the context of the rediscovery of poverty during the 1960s. It examines how social and economic changes, including the growth of consumer credit and the re-housing of large numbers of Dubliners, combined to make illegal moneylending more visible. Historical accounts of Ireland in the 1960s have had a top down focus on economic policy and growth. Here, the focus is shifted to personal rather state finances to offer a more nuanced portrayal of a decade often understood as a boom one. Moreover, analysing the nature and conclusions of the tribunal lays bare the contemporary resistance to those attempting to reframe the problem of poverty.

Detailed analysis of a site near Cincinnati, Ohio, shows that 14C ages of samples in a single geologic unit can have a range of several thousand years and ages from different stratigraphic units can overlap. At the Sharonville site, four 14C samples from organic silt below glaciogenic deposits have an inverted chronologic sequence, suggesting contamination, but nevertheless they indicate the silt was deposited before 27,000 yr B.P. A stump cluster in growth position, wood fragments, and moss from the upper surface of the silt may differ by as much as 2300 14C yr. Five ages from the stump cluster constrain the timing of a glacier advance of the Laurentide ice sheet to its southern limit in the Cincinnati area at 19,670 ± 68 yr B.P. Overlying glaciogenic sediments contain transported wood that may be as much as 3200 yr older than the advance. This range of ages points out that, for a given site, several age measurements are required to determine when a glacier advance occurred. Because the measured ages in this study span the entire interval suggested for a twofold sequence of advance, retreat, and readvance of the margin of the Miami sublobe, we suggest a single advance to its terminal position in the Cincinnati area as an alternate hypothesis for testing.

The extent to which risk for French as a second language (L2) reading and language learning impairment are distinct and can be predicted using first language (L1) predictors was examined in English-speaking students in total French immersion programs. A total of 86 children were tested in fall of kindergarten, spring kindergarten, and spring Grade 1 using an extensive battery of L1 predictor tests (in kindergarten) and L2 outcome tests (in Grade 1). Analyses of the kindergarten predictor scores revealed distinct underlying components, one related to reading and one to oral language. Further analyses revealed that phonological awareness, phonological access, and letter-sound knowledge in L1 were significant predictors of risk for reading difficulties in L2 while performance on L1 sentence repetition, phonological awareness, and tense marking tests in kindergarten were the best predictors of risk for L1 and L2 oral language difficulties. Both fall- and spring-kindergarten predictors predicted Grade 1 outcomes to a significant extent, with the spring-kindergarten predictors being more accurate. These results provide support for distinctive risk profiles for L2 oral language and reading difficulty and, furthermore, argue that assessment of L1 abilities can be used to make reasonably accurate predictions of later reading and/or oral language learning difficulties in L2 students.

A survey of muscid flies from Churchill, Manitoba, Canada, in 2007 yielded 155 species. Some components of species richness and composition of this contemporary assemblage were compared with those of a historical (pre-1965) assemblage, and the contribution of the three collecting methods used in the 2007 survey protocol was evaluated. Estimates of species richness indicated that Malaise traps yielded more species than did pan traps or sweep netting, and that species composition did not differ significantly between Malaise trap and pan trap catches. These results suggest that Malaise traps and sweep netting are adequate methods to survey northern Muscidae. We report little difference in estimated species richness and composition between time periods for material collected by sweep netting. When all material from the 2007 survey was pooled, 87% of the pre-1965 species were collected again in 2007. Most nonoverlapping species between time periods were rare in samples and (or) collected by different methods, suggesting a failure to detect as the most likely explanation for their absence in one assemblage. Nevertheless, the proportion of aquatic and semiaquatic species of Spilogona Schnabl was more than twice as high in the list of species not recovered in 2007 than in the pre-1965 assemblage.