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26 results

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Machiavelli: The Prince
  • 2nd edition
  • Niccolo Machiavelli
  • Edited by Quentin Skinner, Russell Price
  • Published online:
    14 July 2020
    Print publication:
    03 January 2019
  • This new edition of the acclaimed translation of Niccolò Machiavelli's The Prince - revised for the first time after thirty years - includes a rewritten and extended introduction by Quentin Skinner. Niccolò Machiavelli is arguably the most famous and controversial figure in the history of political thought. The Prince remains his best-known work, and throws down a challenge that subsequent writers on statecraft and political morality have found impossible to ignore. Quentin Skinner's introduction offers a lucid analysis of Machiavelli's text both as a response to the world of Florentine politics and as a critical engagement with the classical and Renaissance genre of advice-books for princes. This new edition also features an improved timeline of key events in Machiavelli's life, helping the reader place the work in the context of its time, in addition to an enlarged and fully updated bibliography.

  • Creating reasonable antibiograms for antibiotic stewardship programs in nursing homes: Analysis of 260 facilities in a large geographic region, 2016–2017

  • Scott K. Fridkin, Jacob Pack, Giancarlo Licitra, Ziduo Zheng, Russell Watkins, Steve Price, Mayfield Camp, Renee Moore
  • Journal:
    Infection Control & Hospital Epidemiology / Volume 40 / Issue 8 / August 2019
    Published online by Cambridge University Press:
    28 May 2019, pp. 839-846
    Print publication:
    August 2019
  • Objective:

    To determine the best nursing home facility characteristics for aggregating antibiotic susceptibility testing results across nursing homes to produce a useful annual antibiogram that nursing homes can use in their antimicrobial stewardship programs.

    Design:

    Derivation cohort study.

    Setting:

    Center for Medicare and Medicaid Services (CMS) certified skilled nursing facilities in Georgia (N = 231).

    Participants:

    All residents of eligible facilities submitting urine culture specimens for microbiologic testing at a regional referral laboratory.

    Methods:

    Crude and adjusted metrics of antibiotic resistance prevalence (percent of isolates testing susceptible) for 5 bacterial species commonly recovered from urine specimens were calculated using mixed linear models to determine which facility characteristics were predictive of testing antibiotic susceptibility.

    Results:

    In a single year, most facilities had an insufficient number of isolates tested to create facility-specific antibiograms: 49% of facilities had sufficient Escherichia coli isolates tested, but only about 1 in 10 had sufficient isolates of Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis, or Pseudomonas aeruginosa. After accounting for antibiotic tested and age of the patient, facility characteristics predictive of susceptibility were: E. coli, region, year, average length of stay; K. pneumoniae, region, bed size; P. mirabilis, region; and for E. faecalis or P. aerginosa no facility parameter remained in the model.

    Conclusions:

    Nursing homes often have insufficient data to create facility-specific antibiograms; aggregating data across nursing homes in a region is a statistically sound approach to overcoming data shortages in nursing home stewardship programs.

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