Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

11 results

  • 7 - Cytopathology of Central Nervous System

  • Edited by Ji-Weon Park, Rush University, Chicago, Paolo Gattuso, Rush University, Chicago, Vijaya B. Reddy, Rush University, Chicago, Shahla Masood, University of Florida
  • Book:
    Differential Diagnosis in Cytopathology
    Published online:
    05 March 2021
    Print publication:
    06 May 2021, pp 201-250

  • Summary

    Cytopathological evaluation of central nervous system (CNS) lesions include evaluation of cerebrospinal fluid (CSF) and smears or crushed preparations of specimens submitted as intraoperative consultation following craniotomy or stereotactic CT guided needle biopsy technique. These specimens not only require a good understanding of the general concepts of cytopathology, but also needs an adequate knowledge of various neurological diseases and neuroanatomy. The cytopathologist must be able to correlate the clinical and radiological information and have a good understanding of clinicopathologic entities and their anatomical locations in the CNS.

Lung and Mediastinum Cytohistology
  • Edited by Syed Z. Ali, Grace C. H. Yang
  • Published online:
    05 January 2013
    Print publication:
    01 January 2000
  • Each volume in this richly illustrated series, sponsored by the Papanicolaou Society of Cytopathology, provides an organ-based approach to the cytological and histological diagnosis of small tissue samples. Benign, pre-malignant and malignant entities are presented in a well-organized and standardized format, with high-resolution color photomicrographs, tables, tabulated specific morphologic criteria and appropriate ancillary testing algorithms. Example vignettes allow the reader to assimilate the diagnostic principles in a case-based format. This volume provides comprehensive coverage of lung and mediastinal cytopathology. It presents a correlation of findings from fine-needle aspiration and exfoliative cytology and histologic findings obtained via core needle biopsies and surgical specimens. With a focus on malignant tumors, the full spectrum of inflammatory disorders, infectious diseases, hyperplasias and benign tumor or tumor-like lesions are also covered in detail. With over 500 printed photomicrographs and a CD-ROM offering all images in a downloadable format, this is an important resource for all anatomic pathologists.

  • 9 - Uncommon primary neoplasms

  • Edited by Syed Z. Ali, The Johns Hopkins University School of Medicine, Grace C. H. Yang, Cornell University, New York
  • Book:
    Lung and Mediastinum Cytohistology
    Published online:
    05 January 2013
    Print publication:
    01 January 2000, pp 168-187

  • Summary

    MALIGNANT MESOTHELIOMA

    Clinical features

    Malignant mesothelioma (MM) is a rare tumor that is strongly linked to asbestos exposure and has a poor prognosis. The patient’s clinical history and radiologic findings are important in making a diagnosis of MM. The diagnosis of MM may be made from pleural effusion fluid, percutaneous pleural biopsy, or thoracoscopic pleural biopsy. MMs are classified as epithelioid, sarcomatoid, or mixed. Typically only the epithelioid and mixed type MMs are seen in cytologic specimens as the sarcomatoid type MM tends not to shed cells into the pleural space.

    Treatment options for patients with MM include surgery (extrapleural pneumonectomy or pleural decortication), radiation therapy, and chemotherapy; however, the prognosis is generally poor despite therapy.

    Radiographic features

    Radiographically, MM typically presents as a diffuse pleural thickening. Computed tomography is the preferred imaging modality.

    Cytologic features

    On fine needle aspiration (FNA), epithelioid MM shows cellular smears with variably sized cellular fragments and some single cells (Fig. 9.1). The neoplastic cells are uniform with round nuclei and often prominent nucleoli. Binucleation is frequent and fine cytoplasmic lipid vacuoles are often present (Fig. 9.2). Although some fragments may show three-dimensional gland-like architecture, typical cellular pattern of MM on FNA is that of flat sheets. The latter feature may create diagnostic issues with peripherally located adenocarcinoma in situ (bronchioloalveolar carcinoma).