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Objectives/Goals: Team science (TS) competency is important for translational science team collaboration. However, there are few educators available to assist teams. Asynchronous learning is an effective strategy for delivering TS content. The goal of this project is to expand TS education by providing online access to our learners using online modules. Methods/Study Population: The Collaboration and Team Science (CaTS) team at the University of Cincinnati provides a robust TS education and training program. As the need for team science gains recognition, CaTS has received increased requests for services, leading to a need to broaden TS offerings. To address this demand, the CaTS team created “Team Science 101,” an online, asynchronous, series of 15 modules covering basic team science concepts. Each module consists of an educational recording lasting an average of 20 minutes, optional topic resources, pre- and post-module surveys assessing learners’ confidence and satisfaction, post-module knowledge checks, and evaluation questions. Upon completing all modules, participants receive a completion certificate. Results/Anticipated Results: TS 101 will be piloted with a group of participants who expressed interest in asynchronous TS content and will be adjusted based on the feedback received. The associated pre- and post-module survey, post-module knowledge check, and evaluation questions will be monitored to determine learning levels and improve TS 101 overall. Canvas is the educational platform that houses these modules, allowing for participant follow-up and scalable dissemination. The CaTS team plans to disseminate TS 101 nationally and internationally for anyone interested in this resource. Discussion/Significance of Impact: There is a national effort to collect and curate TS education, training, and toolkits. TS 101 will be a useful educational tool that will expand the reach of team science educators, provide the foundation for educators to explore topics more deeply by building on the module topics, and provide education to broader audiences who lack access to TS experts.
Objectives/Goals: To present findings from a focus group study that evaluate clinical research professionals’ (CRPs) team science learning preferences. The study aims to better understand CRPs’ experiential perceptions of team science skills, training gaps, team cohesion, conflict, and contributions for their preferred team science training. Methods/Study Population: This study targeted CRPs across various roles in Academic Health Centers via focus groups. The focus groups will assess current skills, identify training gaps, and share experiences on team cohesion, team conflict, team contribution, and their thoughts and perceptions about clinical research professional team science training. The focus groups will be held via Zoom in the Autumn of 2024 with volunteer participants from an initial survey that was conducted earlier in 2024. We will report on combined data from multiple 90-minute focus groups, with approximately 6 participants per session. Results/Anticipated Results: The focus group facilitator’s guide includes questions informed by the CRP team science learning needs assessment results and other questions on team issues that would benefit from focused training. Focus group methods and demographic characteristics of the participants by role and experience level will also be presented. Qualitative analyses of recorded focus-group discussions will present key themes by demographic groups, and as a whole, these data will contribute to the development of CRP team science educational programs and toolkits. Discussion/Significance of Impact: CRPs are vital members of clinical translational science teams. Overlooking CRP team science training can negatively affect the efficiency and effectiveness of the clinical translational science enterprise. CRP team science skills will foster a more collaborative and productive research environment.
Clinical research professionals (CRPs) are essential members of research teams serving in multiple job roles. However, recent turnover rates have reached crisis proportions, negatively impacting clinical trial metrics. Gaining an understanding of job satisfaction factors among CRPs working at academic medical centers (AMCs) can provide insights into retention efforts.
Materials/Methods:
A survey instrument was developed to measure key factors related to CRP job satisfaction and retention. The survey included 47 rating items in addition to demographic questions. An open-text question solicited respondents to provide their top three factors for job satisfaction. The survey was distributed through listservs of three large AMCs. Here, we present a factor analysis of the instrument and quantitative and qualitative results of the subsequent survey.
Results:
A total of 484 CRPs responded to the survey. A principal components analysis with Varimax rotation was performed on the 47 rating items. The analysis resulted in seven key factors and the survey instrument was reduced to 25 rating items. Self-efficacy and pride in work were top ranked in the quantitative results; work complexity and stress and salary and benefits were top ranked in the qualitative findings. Opportunities for education and professional development were also themes in the qualitative data.
Discussion:
This study addresses the need for a tool to measure job satisfaction of CRPs. This tool may be useful for additional validation studies and research to measure the effectiveness of improvement initiatives to address CRP job satisfaction and retention.
Background: Duchenne muscular dystrophy (DMD) is caused by DMD gene mutations. Delandistrogene moxeparvovec is an investigational gene transfer therapy, developed to address the underlying cause of DMD. We report findings from Part 1 (52 weeks) of the two-part EMBARK trial (NCT05096221). Methods: Key inclusion criteria: Ambulatory patients aged ≥4-<8 years with a confirmed DMD mutation within exons 18–79 (inclusive); North Star Ambulatory Assessment (NSAA) score >16 and <29 at screening. Eligible patients were randomized 1:1 to intravenous delandistrogene moxeparvovec (1.33×1014 vg/kg) or placebo. The primary endpoint was change from baseline in NSAA total score to Week 52. Results: At Week 52 (n=125), the primary endpoint did not reach statistical significance, although there was a nominal difference in change from baseline in NSAA total score in the delandistrogene moxeparvovec (2.6, n=63) versus placebo groups (1.9, n=61). Key secondary endpoints (time to rise, micro-dystrophin expression, 10-meter walk/run) demonstrated treatment benefit in both age groups (4-5 and 6-7 years; p<0.05).There were no new safety signals, reinforcing the favorable and manageable safety profile observed to date. Conclusions: Based on the totality of functional assessments including the timed function tests, treatment with delandistrogene moxeparvovec indicates beneficial modification of disease trajectory.
The knowledge, skills, and abilities needed for clinical research professionals (CRPs) are described in the Joint Task Force (JTF) for Clinical Trial Competencies Framework as a basis for leveled educational programs, training curricula, and certification. There is a paucity of literature addressing team science competencies tailored to CRPs. Gaps in training, research, and education can restrict their capability to effectively contribute to team science.
Materials/Methods:
The CRP Team Science team consisted of 18 members from 7 clinical and translational science awarded institutions. We employed a multi-stage, modified Delphi approach to define “Smart Skills” and leveled team science skills examples using individual and team science competencies identified by Lotrecchiano et al.
Results:
Overall, 59 team science Smart Skills were identified resulting in 177 skills examples across three levels: fundamental, skilled, and advanced. Two examples of the leveled skillsets for individual and team competencies are illustrated. Two vignettes were created to illustrate application for training.
Discussion:
This work provides a first-ever application of team science for CRPs by defining specific individual and team science competencies for each level of the CRP career life course. This work will enhance the JTF Domains 7 (Leadership and Professionalism) and 8 (Communication and Teamwork) which are often lacking in CRP training programs. The supplement provides a full set of skills and examples from this work.
Conclusion:
Developing team science skills for CRPs may contribute to more effective collaborations across interdisciplinary clinical research teams. These skills may also improve research outcomes and stabilize the CRP workforce.
Translational science (TS) teams develop and conduct translational research. Academic TS teams can be categorized under three constituency groups: trainees and faculty, clinical research professionals (CRP), and community partners. Our study objectives were to define individual and team competencies of these three constituency groups during their career life course and determine relative importance and the level of mastery of each of the competencies needed at different stages of their life course.
Methods:
Each group was composed of experts for their constituency group. We applied individual and team competencies in TS teams by Lotrecchiano et al. (2020) as a starting point for structured expert discussions following a modified Delphi approach that we adapted based on the emergent needs and insights per constituency group.
Results:
The degree of relevance and level of mastery for individual and team competencies varies for trainees and faculty members across the career life course based on opportunities provided and relative importance at that career stage. However, CRPs enter TS teams at various career stages with fundamental, skilled, or advanced levels of smart skills that may or may not be contextual to their role. Community partners equally possess and develop competencies in a non-linear and contextual fashion that are required to facilitate constructive, bi-directional collaboration with other members of TS teams.
Conclusions:
Team science competencies across the career life course do not develop linearly among different constituency groups and require an adaptive framework to enhance TS team effectiveness.
Galaxy gas kinematics are sensitive to the physical processes that contribute to a galaxy’s evolution. It is expected that external processes will cause more significant kinematic disturbances in the outer regions, while internal processes will cause more disturbances for the inner regions. Using a subsample of 47 galaxies ($0.27<z<0.36$) from the Middle Ages Galaxy Properties with Integral Field Spectroscopy (MAGPI) survey, we conduct a study into the source of kinematic disturbances by measuring the asymmetry present in the ionised gas line-of-sight velocity maps at the $0.5R_e$ (inner regions) and $1.5R_e$ (outer regions) elliptical annuli. By comparing the inner and outer kinematic asymmetries, we aim to better understand what physical processes are driving the asymmetries in galaxies. We find the local environment plays a role in kinematic disturbance, in agreement with other integral field spectroscopy studies of the local universe, with most asymmetric systems being in close proximity to a more massive neighbour. We do not find evidence suggesting that hosting an Active Galactic Nucleus contributes to asymmetry within the inner regions, with some caveats due to emission line modelling. In contrast to previous studies, we do not find evidence that processes leading to asymmetry also enhance star formation in MAGPI galaxies. Finally, we find a weak anti-correlation between stellar mass and asymmetry (i.e., high stellar mass galaxies are less asymmetric). We conclude by discussing possible sources driving the asymmetry in the ionised gas, such as disturbances being present in the colder gas phase (either molecular or atomic) prior to the gas being ionised, and non-axisymmetric features (e.g., a bar) being present in the galactic disk. Our results highlight the complex interplay between ionised gas kinematic disturbances and physical processes involved in galaxy evolution.
This book explores the right of access to environmental information, considering both the environmental aspirations which underlie the right and how far these are evidenced in the right's use in practice. The right has a history separate from wider moves towards freedom of information. From its origins in the Rio Declaration to its current embodiment in the Aarhus Convention, a key aim of the right is to promote environmental governance and protect the environment through the provision of environmental information, both proactively and upon request.
However, there is little empirical evidence to show whether the right is achieving these environmental aims, if it is being used for its intended environmental purpose, or even how far it is being viewed as distinct from the general right to information. This book seeks to fill this gap through qualitative research conducted in Scotland, the findings of which highlight that individuals who seek environmental information under the right are often doing so for personal or professional reasons that do not further the right's environmental purpose. This is significant, because if the right is not being used for its intended environmental purpose, then its contribution to environmental governance can be questioned, as can the value of maintaining this specific right, distinct from wider freedom of information laws.
The previous chapter focused on professional users of the right to access environmental information and highlighted the stark mismatch between the expectations which underpin the right’s intended use and how the right is actually used in practice. Professional users serve as a clear example of this mismatch because the underpinning assumptions which animate the right and its legal regimes do not cater for this minority category of users. However, considering this mismatch in that context also provides the opportunity to identify whether the same is true for “personal users”. Personal users – the majority of those using the right – are more likely to be engaging directly with the environmental information held by public authorities and with the right’s environmental and participative aims. Yet, as with those in the professional user category, the individual actors within this second group are also diverse in terms of what motivates them, how they use information obtained and their levels of expertise in engaging with public authorities and the right itself. Thus, mismatches such as those identified in the context of professional users also arise in relation to personal users.
INTRODUCTION
The differences between personal users are key to how they experience and engage with the right of access to environmental information. These differences can be split into two themes. The first of these relates to the motive of personal users, referring to what drives these users to engage with the right and seek access to environmental information. The second theme relates to the levels of expertise that different users hold, encapsulating different aspects such as the ability in seeking proactively disclosed information, drafting and submitting requests for environmental information, and understanding any information accessed under the right. Such variety distinguishes different personal users from each other, creating a complex tapestry of personal users who are each engaging with the right in their own way and for their own reasons.
Although the environment may be intended to be the ultimate beneficiary, within the Aarhus Convention and the Environmental Information (Scotland) Regulations 2004 (EI(S)R) that give it effect in Scotland, users of the right are the actors who can claim direct benefits. It is therefore crucial that analysis of the right considers its users. It is these users who engage with the Convention’s moral duty to “protect and improve the environment for the benefit of present and future generations” and who exercise the right to seek access to environmental information through the proactive disclosure efforts of public authorities and the procedures set out in the EI(S)R. As a result, it is important to build both an appreciation of how the law perceives and constructs a vision of the users of the right to environmental information and an empirical understanding of who the users are and what they are doing.
INTRODUCTION
The starting point for understanding how the Aarhus Convention and the EI(S)R view users of the right is through the broad nature of the moral duty imposed on users to protect and improve the environment by participating in environmental decision-making processes. This duty is significant because it shapes expectations regarding how and why users engage with the right. Specifically, there is an assumption that users will be directly using the environmental information they access to “observe this duty” and fulfil their assumed altruistic, environmentally driven motivations for engaging with the right – a perspective reinforced by the legal instruments that preceded the Aarhus Convention. Further, users are expected to hold the necessary expertise effectively to understand and make use of the information they access for these purposes.
Yet while the Aarhus Convention holds these assumptions regarding those using the right, they are not fully reflected in the Convention’s provisions themselves. Under the Aarhus Convention, it is “the public” who can utilise its procedural rights, with “the public” being defined as:
One or more natural or legal persons, and, in accordance with national legislation or practice, their associations, organizations or groups.
The starting point for the creation of a right to environmental information is “the need to protect, preserve and improve the state of the environment and to ensure sustainable and environmentally sound development”. This need has become all the more pressing at a time of significant anthropogenic environmental change. However, the right of access to environmental information is framed in a way that primarily emphasises the concerns and needs of humanity. While this anthropocentric framing influences the interpretation of the right’s environmental aims, it also emphasises the role of human actors, particularly users of the right, in the operation of the right itself. Yet human actors are not the only actors that exert influence over how the right is guaranteed, implemented and utilised in practice; non-human actors influence how the right to environmental information is guaranteed. Notable examples of such actors include technology and the law, which influence the interactions between other actors, and the environment itself, an actor given limited attention both by the right itself and its implementing legal instruments. The role and impact of these actors remains unexplored, to the detriment both of how the right is implemented in practice and of how it seeks to achieve and understand its own environmental and participative aims. This chapter will discuss how to give better consideration to these actors and, in particular, will argue for the need to give more attention to the environment as an actor.
INTRODUCTION
Actor-Network Theory is concerned with the “the tracing of associations” between different actors in order to understand how they each engage with and interact with each other within society. It is these associations between the different actors which construct the “actor-network”, a network which is built up through the connections made between different actors. Through the construction of the actor-network, Actor-Network Theory provides a useful perspective to analyse and understand the operation of various aspects of society, including the right of access to environmental information.
This book has shown that the reality of the exercise of the right of public access to environmental information is rather different from and more complicated than much of the discussion of the topic suggests. From the Rio Declaration through the Aarhus Convention to the Environmental Information (Scotland) Regulations 2004 (EI(S)R), the provision of information is seen as a means of promoting the development of environmentally engaged citizens and enabling them to participate effectively in decision-making procedures with a view to protecting and enhancing the environment. Only a few of the uses fit well with this vision and, even when they do, users are left frustrated that they are not able to exercise more influence over decision-making procedures. As such, there is a gap between the aspirations of the right and the reality of its use that needs to be considered.
The most basic point perhaps is the low level of awareness of the existence of the particular right to environmental information that is distinct from any entitlements under more general laws on freedom of information and that lies behind information being accessible. Whether or not the use of the right is recognised as such by those involved, the practice does not always match the aspirations that lie behind it. The parties involved are more diverse than can be encapsulated in a single category of “users” or “holders” of information, and their relationships are shaped by their engagement not only with each other but also with a range of non-human actors. In addition, their motivations are often very different from the environmental objectives that providing access to environmental information was designed to serve. The overall result is a system where mismatches arise as a result of different motives and expectations, leading to frustrations and getting in the way of the right always being smoothly and successfully implemented. That different actors will define success in relation to the right differently, particularly in terms of focusing on procedural or substantive outcomes of engaging with the right, adds to the complexity.
In recent decades, the introduction of a right of public access to environmental information has been acclaimed as a major achievement in improving environmental governance across the world and it is frequently asserted that this right “will improve environmental protection”. Yet remarkably little work has been undertaken to examine how the right is being used in practice and whether it is in fact making a difference. This book will provide some answers to those vital questions, building on empirical work in Scotland to identify lessons that are of general application. It offers insights into the workings of the processes for accessing environmental information – who is using them, what information is being sought and for what purposes? – and into whether what is happening in practice lives up to the aspirations that underpin the introduction of the right. The findings reveal a significant mismatch between aspirations and practice that requires consideration of what is currently being achieved and how the position might be improved.
The research behind this book was carried out at the University of Dundee and was supported by a grant from the Economic and Social Research Council (ref. ES/P010067/1), running from January 2018 to June 2020. The investigators who submitted the proposal, Professor Colin Reid in Law and Dr Jonathan Mendel in Geography, were joined by Dr Sean Whittaker as a research assistant until he was appointed Lecturer in Law in late 2019. For the final months of the funded project, this research assistant post was filled by Dr Petya Dragneva who – despite the disruptions caused by the COVID-19 pandemic – was able to do excellent work in preparing interview material for archiving, working on interview transcripts, and other parts of the project. A project website was established and is available at: https://sites.dundee.ac.uk/envinfo.
Analysis of the right of access to environmental information is generally conducted through one of two legal perspectives. The work here offers insights beyond these typical approaches both by drawing more on social theory and through empirical study of how the right is operating in practice. The first conventional approach, relying on a widespread legal methodology, studies the legal framework and also the aims and aspirations that underpin the creation of the right, “grappling with the foundational concepts that inspire the ambitious vision” that lies behind it. The second, narrower approach seeks to examine the right through the doctrinal method of analysis, an approach which focuses on the internal working and operation of “black-letter” law and its position within the legal hierarchy. The latter perspective follows the legal origins of the right and the way it has been embodied. From the Stockholm Declaration through the Rio Declaration and the Aarhus Convention to the measures ensuring its implementation in the EU and Scotland, the recognition and development of the right have been dominated by the law and the legal procedures which give it effect. The doctrinal methodology, with its basis in legal study, thus dominates discussion and analysis of the right of access to environmental information.
Both approaches bring numerous benefits in analysing the right of access to environmental information. The focus on the underlying concepts and ambitions enables access to information to be considered in the wider context of analysing governance. The doctrinal approach, by adopting an internal perspective on the laws that govern the right, offers analysis that can consider the internal logic of these laws and whether they are aligned with the objectives that they are seeking to achieve. However, while both approaches provide valuable perspectives on the right, they do not consider whether the law operates in the “real world” as intended. Described as the gap between “the law in the books” and “the law in action”, there is a risk that relying wholly on either methodology will result in a distorted understanding of the right that is based on how the law was intended to operate or is assumed to be operating rather than how it actually operates in practice.
In recent decades, the introduction of a public right to access environmental information has been acclaimed as a major achievement in improving environmental governance across the world and it is frequently asserted that this right “will improve environmental protection”. This book critically assesses that assertion, examining the operation and impact of the right in practice to see how far what happens in real life matches the assumptions and aspirations that surround the right. Ultimately this leads to an examination of the value of a distinct right to environmental information operating separately from wider rules on transparency and freedom of information.
There can be no doubt that the environment needs greater protection, not least from the overarching issue of climate change and its negative impacts on both humanity and the wider environment. Such global concerns are also felt locally in relation to climate adaptation and mitigation measures, but local concerns also focus on other issues, such as land use and urban planning matters, waste disposal, water quality, noise and smells. An increased interest in environmental matters has led to a more intense desire from the public for greater transparency and involvement in environmental governance. While this interest is seen in non-environmental issues as well, there has been a particular emphasis on transparency, accountability and public participation in the environmental context due to the increased recognition of our shared vulnerability to, and responsibility for, the Earth’s environmental degradation. It is from this recognition that the right of access to environmental information was born.
This right was created as a means of promoting the flow of environmental information between the state and the public, either through proactively publishing environmental information or disclosing environmental information on request. At the core of the right is the assumption that the disclosure of such environmental information will contribute to humanity’s efforts to slow, or even reverse, the degradation of the environment. This will be achieved by promoting the transparency and accountability of public bodies in environmental matters, but even more so by encouraging and enabling public participation in decision-making on environmental issues.
The right of access to environmental information has been the focus of this book so far, but this right does not operate in isolation. Linked to the right of access to environmental information is the right to participate in environmental decision-making procedures. Broadly defined as ensuring the ability for individuals to participate in environmental decisions made by a public authority, the development of this right and its role in protecting and enhancing the environment has occurred in parallel with the right of access to environmental information. Indeed, at the extreme, the right to access information can be presented as a subsidiary matter, existing merely to ensure that public participation can be effective. How far the use of the right to access environmental information is in practice linked to the exercise, and effectiveness, of the right to participate – and the broader efficacy of public participation – are therefore crucial to exploring what these rights are achieving.
INTRODUCTION
The parallel development of the rights to access environmental information and to participate in environmental decision-making is evidenced in the Rio Declaration, which boldly asserted that: “Environmental issues are best handled with the participation of all concerned citizens.” The Rio Declaration was notable not just for this assertion, but for also explicitly linking the provision of environmental information with the ability to effectively participate in environmental decision-making procedures. This position was generally adopted in subsequent legal instruments, particularly the Aarhus Convention, and represented a broader trend towards viewing human rights and “environmental participatory rights” as a connected set of rights.
Yet the stark clarity of the assertion made by the Rio Declaration masks the fact that there is considerable uncertainty over what such participation is supposed to achieve and how it should be made possible. As Lee and Abbot noted: “Participation has a very strong pull on environmental policy making, but its meaning and aims are rarely made clear.” The rationale for promoting participation has been subject to considerable debate, reflecting a divergence in how public participation, and its aims, are conceptualised, with different levels of empowerment for the public involved.