We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
Online ordering will be unavailable from 17:00 GMT on Friday, April 25 until 17:00 GMT on Sunday, April 27 due to maintenance. We apologise for the inconvenience.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
With the increasing accessibility of tools such as ChatGPT, Copilot, DeepSeek, Dall-E, and Gemini, generative artificial intelligence (GenAI) has been poised as a potential, research timesaving tool, especially for synthesising evidence. Our objective was to determine whether GenAI can assist with evidence synthesis by assessing its performance using its accuracy, error rates, and time savings compared to the traditional expert-driven approach.
Methods
To systematically review the evidence, we searched five databases on 17 January 2025, synthesised outcomes reporting on the accuracy, error rates, or time taken, and appraised the risk-of-bias using a modified version of QUADAS-2.
Results
We identified 3,071 unique records, 19 of which were included in our review. Most studies had a high or unclear risk-of-bias in Domain 1A: review selection, Domain 2A: GenAI conduct, and Domain 1B: applicability of results. When used for (1) searching GenAI missed 68% to 96% (median = 91%) of studies, (2) screening made incorrect inclusion decisions ranging from 0% to 29% (median = 10%); and incorrect exclusion decisions ranging from 1% to 83% (median = 28%), (3) incorrect data extractions ranging from 4% to 31% (median = 14%), (4) incorrect risk-of-bias assessments ranging from 10% to 56% (median = 27%).
Conclusion
Our review shows that the current evidence does not support GenAI use in evidence synthesis without human involvement or oversight. However, for most tasks other than searching, GenAI may have a role in assisting humans with evidence synthesis.
The outbreak of major epidemics, such as COVID-19, has had a significant impact on supply chains. This study aimed to explore knowledge innovation in the field of emergency supply chain during pandemics with a systematic quantitative analysis.
Methods
Based on the Web of Science (WOS) Core Collection, proposing a 3-stage systematic analysis framework, and utilizing bibliometrics, Dynamic Topic Models (DTM), and regression analysis to comprehensively examine supply chain innovations triggered by pandemics.
Results
A total of 888 literature were obtained from the WOS database. There was a surge in the number of publications in recent years, indicating a new field of research on Pandemic Triggered Emergency Supply Chain (PTESC) is gradually forming. Through a 3-stage analysis, this study identifies the literature knowledge base and distribution of research hotspots in this field and predicts future research hotspots and trends mainly boil down to 3 aspects: pandemic-triggered emergency supply chain innovations in key industries, management, and technologies.
Conclusions
COVID-19 strengthened academic exchange and cooperation and promoted knowledge output in this field. This study provides an in-depth perspective on emergency supply chain research and helps researchers understand the overall landscape of the field, identifying future research directions.
This study delves into the intricate relationship between chief executive officers' (CEOs') experiences of poverty and the digital transformation of their firms. Employing comprehensive data collection on CEOs' birthplaces and leveraging advanced text analytics to quantify digitalization, our analysis encompasses a wide array of listed companies in China. The findings reveal that CEOs' impoverished experiences exert a detrimental influence on their firms' digital transformation efforts, primarily due to a lack of motivation and social resources necessary for such initiatives. However, this adverse effect can be ameliorated when CEOs gain access to substantial social resources in later life. Our conclusions are robust, supported by rigorous testing, and underscore not only the impact of CEOs' early-life poverty on corporate digitalization but also the potential for overcoming these challenges through the acquisition of external social resources and connections in adulthood. This study contributes significantly to existing literature and offers practical implications for enhancing corporate digital transformation strategies.
This study explores an interesting fluid–structure interaction scenario: the flow past a flexible filament fixed at two ends. The dynamic performance of the filament under various inclination angles ($\theta$) was numerically investigated using the immersed boundary method. The motion of the filament in the $\theta$–$Lr$ space was categorised into three flapping modes and two stationary modes, where $Lr$ is the ratio of filament length to the distance between its two ends. The flow fields for each mode and their transitions were introduced. A more in-depth analysis was carried out for flapping at a large angle (FLA mode), which is widely present in the $\theta$–$Lr$ space. The maximum width $W$ of the time-averaged shape of the filament has been shown to strongly correlate with the flapping frequency. After non-dimensionalising based on $W$, the flapping frequency shows little variation across different $Lr$ and $\theta$. Moreover, two types of lift variation process were also identified. Finally, the total lift, drag and lift-to-drag ratio of the system were studied. Short filaments, such as those with $Lr\leqslant 1.5$, were shown to significantly increase lift and the lift-to-drag ratio over a wide range of $\theta$ compared with a rigid plate. Flow field analysis concluded that the increases in pressure difference on both sides of the filament, along with the upper part of the flexible filament having a normal direction closer to the $y$ direction, were the primary reasons for the increase in lift and lift-to-drag ratio. This study can provide some guidance for the potential applications of flexible structures.
Serotonin (5-hydroxytryptamine, 5-HT) is a key monoamine neurotransmitter in insects, which regulates neural functions and influences various developmental and physiological processes by binding to its receptors. In this study, we investigate the molecular characteristics, phylogenetic relationships, and expression patterns of the 5-HT7 receptor (Cf5-HT7) in Chrysopa formosa, with a focus on its potential involvement in developmental and diapause regulation. The Cf5-HT7 gene was identified and cloned from the C. formosa transcriptome, revealing an open reading frame of 1788 bp encoding a 596 amino acid protein. Sequence analysis confirmed that Cf5-HT7 is a typical class A G protein-coupled receptor, characterised by seven transmembrane domains and several post-translational modifications, including palmitoylation and N-glycosylation sites. Phylogenetic analysis revealed that Cf5-HT7 is most closely related to the 5-HT7 receptor from Chrysoperla carnea, with high conservation of key motifs involved in ligand binding and receptor activation. Expression analysis across different developmental stages of C. formosa showed that Cf5-HT7 is highly expressed in the first instar larvae, with significant upregulation observed during the prepupal stage. Under diapause-inducing conditions, Cf5-HT7 expression is modulated in a stage-specific manner, showing a marked decrease at the onset of diapause, followed by a significant increase during the mid-to-late diapause maintenance phase. These findings suggest that it plays a pivotal role in regulating development and diapause processes in C. formosa, offering new insights into the molecular mechanisms governing insect life cycle transitions. This study lays the groundwork for future research into the functional roles of 5-HT7 receptors in insect physiology and their potential applications in manipulating diapause.
The Second Sino-Japanese War (1937-1945) occupies an integral position in the memory politics of the People's Republic of China (PRC). In recent years, dominant representations of the war create a memory discourse which portrays the heroic triumph of the Chinese people led by the Chinese Communist Party (CCP) over Japan. This article shows how the war has been remembered from the victory of the Communist revolution in 1949 to the present in the PRC. It contributes to the debate on the effectiveness and limitations of the monopoly of war memory by the CCP.
In this paper, we report the spatiotemporal dynamics of an intraguild predation (IGP)-type predator–prey model incorporating harvesting and prey-taxis. We first discuss the local and global existence of the classical solutions in N-dimensional space. It is found that the model has a global classical solution when controlling the prey-taxis coefficient in a certain range. Thereafter, we focus on the existence of the steady-state bifurcation. Moreover, we theoretically investigate the properties of the bifurcating solution near the steady-state bifurcation critical threshold. As a consequence, the spatial pattern formation of this model can be theoretically confirmed. Importantly, by means of rigorous theoretical derivation, we provide discriminant criteria on the stability of the bifurcating solution. Finally, the complicated patterns are numerically displayed. It is demonstrated that the harvesting and prey-taxis significantly affect the pattern formation of this IGP-type predator–prey model. Our main results of this paper reveal that (i) The repulsive prey-taxis could destabilize the spatial homogeneity, while the attractive prey-taxis effect and self-diffusion will stabilize the spatial homogeneity of this model. (ii) Numerical results suggest that over-harvesting for prey or predators is not advisable, it can lead to an ecological imbalance due to a significant reduction in population numbers. However, harvesting within a certain range is a feasible approach.
Intermittent swimming behaviour is commonly observed in larval zebrafish, often attributed to energy-saving mechanisms. In this study, we utilize a hybrid approach combining deep reinforcement learning and the immersed boundary–lattice Boltzmann method to train a larval zebrafish-like swimmer to reach a target with minimized energy expenditure. We find that when the tail-beat period is fixed, continuous swimming emerges as the optimal strategy. However, when the tail-beat period is allowed to vary, intermittent swimming proves superior in energy performance, achieved through reductions in tail-beat amplitude and frequency. Our detailed analysis reveals that intermittent swimmers employ rapid backward tail flicks to attain high speeds, coupled with slower forward tail flicks and coasting phases to conserve energy. Furthermore, we derive scaling laws governing the swimming performance of trained fish. These results offer valuable insights into the intermittent swimming patterns of fish, with implications for understanding bio-inspired locomotion and informing the design of energy-efficient aquatic systems.
Data for Policy (dataforpolicy.org), a trans-disciplinary community of research and practice, has emerged around the application and evaluation of data technologies and analytics for policy and governance. Research in this area has involved cross-sector collaborations, but the areas of emphasis have previously been unclear. Within the Data for Policy framework of six focus areas, this report offers a landscape review of Focus Area 2: Technologies and Analytics. Taking stock of recent advancements and challenges can help shape research priorities for this community. We highlight four commonly used technologies for prediction and inference that leverage datasets from the digital environment: machine learning (ML) and artificial intelligence systems, the internet-of-things, digital twins, and distributed ledger systems. We review innovations in research evaluation and discuss future directions for policy decision-making.
Increasing daylight exposure might be a simple way to improve mental health. However, little is known about daylight-symptom associations in depressive disorders.
Methods
In a subset of the Australian Genetics of Depression Study (N = 13,480; 75% female), we explored associations between self-reported number of hours spent in daylight on a typical workday and free day and seven symptom dimensions: depressive (overall, somatic, psychological); hypo-manic-like; psychotic-like; insomnia; and daytime sleepiness. Polygenic scores for major depressive disorder (MDD); bipolar disorder (BD); and schizophrenia (SCZ) were calculated. Models were adjusted for age, sex, shift work status, employment status, season, and educational attainment. Exploratory analyses examined age-stratified associations (18–24 years; 25–34 years; 35–64 years; 65 and older). Bonferroni-corrected associations (p < 0.004) are discussed.
Results
Adults with depression reported spending a median of one hour in daylight on workdays and three hours on free days. More daylight exposure on workdays and free days was associated with lower depressive (overall, psychological, somatic) and insomnia symptoms (p’s<0.001), but higher hypo-manic-like symptoms (p’s<0.002). Genetic loading for MDD and SCZ were associated with less daylight exposure in unadjusted correlational analyses (effect sizes were not meaningful). Exploratory analyses revealed age-related heterogeneity. Among 18–24-year-olds, no symptom dimensions were associated with daylight. By contrast, for the older age groups, there was a pattern of more daylight exposure and lower insomnia symptoms (p < 0.003) (except for 25–34-year-olds on free days, p = 0.019); and lower depressive symptoms with more daylight on free days, and to some extent workdays (depending on the age-group).
Conclusions
Exploration of the causal status of daylight in depression is warranted.
The Early-Middle Jurassic impression/compression macroflora and the palynoflora from the Qaidam Basin in the northeastern Qinghai-Xizang (Tibetan) Plateau have been well studied; however, fossil wood from this region has not been previously documented systematically. Here, we describe an anatomically well-preserved fossil wood specimen from the Lower Jurassic Huoshaoshan Formation at the Dameigou section in northern Qinghai Province, northwestern China. This fossil exhibits typical Metapodocarpoxylon Dupéron-Laudoueneix et Pons anatomy with usually araucarian radial tracheid pits and variable cross-field pits, representing a new record for Metapodocarpoxylon in the Qaidam Basin. This discovery indicates that trees with this type of wood anatomy were not confined to northern Gondwana but also grew in more northerly regions in Laurasia. The wood displays distinct growth rings, with abundant, well-formed earlywood and narrow latewood. This observation, along with previous interpretations based on macroflora, palynoflora and sedimentological data, suggests that a warm and humid climate with mild seasonality prevailed in the region during the Early Jurassic.
This chapter traces the cultural history of lotus in the Chinese tradition: from its appearance in The Classic of Poetry and Han dynasty rhapsodies to the exuberant wordplay on ‘lotus’/’love” in the popular songs of the Southern Dynasties, from the flower of carnal desires to a symbol of enlightenment in Buddhism, from the neo-Confucian appropriation of the lotus as a sign of moral purity to the name of the most notorious female character in Chinese fiction, lotus is inscribed with various literary, cultural, social, and religious significance. Focusing on the changing and expanding story of the lotus, this chapter suggests that the lotus is a plant of hybridity, a site of contested meanings, and that its botanical and literary lives are intricately intertwined with the social and cultural histories of China.
The emotion regulation network (ERN) in the brain provides a framework for understanding the neuropathology of affective disorders. Although previous neuroimaging studies have investigated the neurobiological correlates of the ERN in major depressive disorder (MDD), whether patients with MDD exhibit abnormal functional connectivity (FC) patterns in the ERN and whether the abnormal FC in the ERN can serve as a therapeutic response signature remain unclear.
Methods
A large functional magnetic resonance imaging dataset comprising 709 patients with MDD and 725 healthy controls (HCs) recruited across five sites was analyzed. Using a seed-based FC approach, we first investigated the group differences in whole-brain resting-state FC of the 14 ERN seeds between participants with and without MDD. Furthermore, an independent sample (45 MDD patients) was used to evaluate the relationship between the aforementioned abnormal FC in the ERN and symptom improvement after 8 weeks of antidepressant monotherapy.
Results
Compared to the HCs, patients with MDD exhibited aberrant FC between 7 ERN seeds and several cortical and subcortical areas, including the bilateral middle temporal gyrus, bilateral occipital gyrus, right thalamus, calcarine cortex, middle frontal gyrus, and the bilateral superior temporal gyrus. In an independent sample, these aberrant FCs in the ERN were negatively correlated with the reduction rate of the HAMD17 score among MDD patients.
Conclusions
These results might extend our understanding of the neurobiological underpinnings underlying unadaptable or inflexible emotional processing in MDD patients and help to elucidate the mechanisms of therapeutic response.
The three-dimensional flow field past an I-shaped dual-step cylinder has been obtained by numerical integration of the Navier–Stokes equations at Reynolds number ($Re_D$) 150. The I-shaped cylinder consisted of two large-diameter (D) cylinders with a small-diameter (d) cylinder in between. With a view to exploring the vortex dynamics and structural loads, simulations were performed for eight different lengths $l$ of the small cylinder, varied from $l/D=10$ to 0.2 for a fixed diameter ratio $D/d=2$. When the length of the small cylinder is sufficiently large, the wake behind the I-shaped cylinder is similar to the wake behind the single-step cylinder (Tian et al., J. Fluid Mech., vol. 891, 2020, A24). As the small cylinder length decreases, the enhanced interactions between the two steps make the present wake deviate from the wake of the single-step cylinder, leading to four different wake modes distinguished by different combinations of vortex cells. The physical formation mechanisms were analysed in terms of the vortex dynamics. Besides the wake flow, the streamwise vortices around the I-shaped step cylinder were also investigated. A pair of edge vortices and a junction vortex were identified for $l/D \geq ~1$. When the gap between the two steps becomes too small, $l/D \leq ~0.2$, the junction vortex disappears, and only a pair of edge vortices exists. Varying the distance between the two steps strongly affects the structural loads (drag and lift) along the I-shaped cylinder. The dependence of the loads on $l/D$ was readily explained by the different wake modes.
Depressive and anxiety disorders constitute a major component of the disease burden of mental disorders in China.
Aims
To comprehensively evaluate the disease burden of depressive and anxiety disorders in China.
Method
The raw data is sourced from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021. This study presented the disease burden by prevalence and disability-adjusted life years (DALYs) of depressive and anxiety disorders at both the national and provincial levels in China from 1990 to 2021, and by gender (referred to as 'sex' in the GBD 2021) and age.
Results
From 1990 to 2021, the number of depressive disorder cases (from 34.4 to 53.1 million) and anxiety disorders (from 40.5 to 53.1 million) increased by 54% (95% uncertainty intervals: 43.9, 65.3) and 31.2% (19.9, 43.8), respectively. The age-standardised prevalence rate of depressive disorders decreased by 6.4% (2.9, 10.4), from 3071.8 to 2875.7 per 100 000 persons, while the prevalence of anxiety disorders remained stable. COVID-19 had a significant adverse impact on both conditions. There was considerable variability in the disease burden across genders, age groups, provinces and temporal trends. DALYs showed similar patterns.
Conclusion
The burden of depressive and anxiety disorders in China has been rising over the past three decades, with a larger increase during COVID-19. There is notable variability in disease burden across genders, age groups and provinces, which are important factors for the government and policymakers when developing intervention strategies. Additionally, the government and health authorities should consider the potential impact of public health emergencies on the burden of depressive and anxiety disorders in future efforts.
In certain scenarios, the large footprint of a robot is not conducive to multi-robot cooperative operations. This paper presents a generalized single-loop parallel manipulator with remote center of motion (GSLPM-RCM), which addresses this issue by incorporating a reconfigurable base. The footprint of this RCM manipulator can be adjusted by varying the parameters of the reconfigurable base. First, utilizing configuration evolution, a reconfigurable base is constructed based on the principle of forming RCM motion. Then, according to the modular analysis method, the inverse kinematics of this parallel RCM manipulator is analyzed, and the workspace is also analyzed. Subsequently, the motion/force transmissibility of this RCM manipulator is analyzed by considering its single-loop and multi-degree of freedom characteristics. Leveraging the workspace index and transmissibility indices, dimension optimization of the manipulator is implemented. Finally, the influence of the reconfigurable base on the workspace and the transmissibility performance of the optimized manipulator is studied.