In this paper, we will discuss stability and reliability requirements of organic electronic devices and evaluate different encapsulation approaches enabling stable organic ultra-thin and stretchable devices. We highlight the differences in requirements and encapsulation approaches for applications, including organic light emitting diode (OLED) displays, OLED lighting, photovoltaics, and sensors. Stability and reliability requirements addressed in this paper cover light management, mechanical characteristics, chemical compatibility, form factors, and durability. While flexible organic electronic devices have already been demonstrated and commercialized, so far only prototypes of ultra-thin and stretchable devices have been demonstrated. The technological progress is promising and by identifying the gaps between prototyping and product realization, we intend to stimulate further research and development in this area.