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Sickle cell disease (SCD) is hallmarked by recurrent episodes of severe acute pain and the risk for chronic pain. Remote peer support programs have been shown to effectively improve health outcomes for many chronic conditions. The objective of this study was to examine the feasibility and acceptability of an online peer mentoring program (iPeer2Peer program) for adolescents with SCD.
Method:
A waitlist pilot randomized controlled trial was conducted. Adolescents randomized to the intervention group were matched with trained peer mentors (19–25 years; successfully managing their SCD), consisting of up to 10 sessions of approximately 30-min video calls over a 15-week period. The control group received standard care. The primary outcomes were rates of accrual, withdrawal, and adherence to iP2P program/protocol, with secondary outcomes identifying topics of mentorship–mentee conversations through qualitative analysis.
Results:
Twenty-eight participants (14 intervention; 14 control) were randomized to the study (mean age: 14.8 ± 1.7 years; 57% female). Accrual rate was 80% (28/35) and withdrawal rate was 18% (5/28), with 28% (4/14) adhering to the iP2P program; however, 71% (10/14) of adolescents in the intervention completed at least one call. Based on content analysis of 75 mentor–mentee calls, three distinct content categories emerged: impact of SCD, self-management, transitioning to adulthood with SCD, and general topics.
Conclusion:
The results from this pilot study suggest that the current iteration of the iP2P SCD program lacks feasibility. Future research with the iP2P program can focus improved engagement via personalized mentoring, variable communication avenues, and an emphasis on gender.
The Minnesota Longitudinal Study of Risk and Adaptation (MLSRA) is a landmark prospective, longitudinal study of human development focused on a sample of mothers experiencing poverty and their firstborn children. Although the MLSRA pioneered a number of important topics in the area of social and emotional development, it began with the more specific goal of examining the antecedents of child maltreatment. From that foundation and for more than 40 years, the study has produced a significant body of research on the origins, sequelae, and measurement of childhood abuse and neglect. The principal objectives of this report are to document the early history of the MLSRA and its contributions to the study of child maltreatment and to review and summarize results from the recently updated childhood abuse and neglect coding of the cohort, with particular emphasis on findings related to adult adjustment. While doing so, we highlight key themes and contributions from Dr Dante Cicchetti’s body of research and developmental psychopathology perspective to the MLSRA, a project launched during his tenure as a graduate student at the University of Minnesota.
This Element introduces Aristotle's doctrine of hylomorphism, which provides an account of substances in terms of their 'matter' and 'form', adapting and applying it to the interface between physics and biology. It begins by indicating some reasons for the current revival of hylomorphism and by suggesting a way of classifying the confusing array of hylomorphisms that have arisen. It argues that, in order for composite entities to have irreducible causal powers which make a difference to how nature unfolds, they must have substantial forms which transform their matter such that the powers of their physical parts are grounded in the composite entity as a whole. It suggests how a contemporary form of hylomorphism might contribute to the philosophy of biology by grounding the non-intentional form of teleology that features in the identity conditions of biological systems, affirming a real distinction between living organisms and heaps of matter. This title is also available as Open Access on Cambridge Core.
Yarkoni's analysis clearly articulates a number of concerns limiting the generalizability and explanatory power of psychological findings, many of which are compounded in infancy research. ManyBabies addresses these concerns via a radically collaborative, large-scale and open approach to research that is grounded in theory-building, committed to diversification, and focused on understanding sources of variation.
This volume explores some of the key features of popular politics and resistance before and after 1994. It looks at continuities and changes in the forms of struggle and ideologies involved, as well as the significance of post-apartheid grassroots politics. Is this a new form of politics or does it stand as a direct descendent of the insurrectionary impulses of the late apartheid era? Posing questions about continuity and change before and after 1994 raises key issues concerning the nature of power and poverty in the country. Contributors suggest that expressions of popular politics are deeply set within South African political culture and still have the capacity to influence political outcomes. The introduction by William Beinart links the papers together, places them in context of recent literature on popular politics and ‘history from below’ and summarises their main findings, supporting the argument that popular politics outside of the party system remain significant in South Africa and help influence national politics. The roots of this collection lie in post-graduate student research conducted at the University of Oxford in the early twenty-first century.
The purpose of this study was to assess the pattern of adult dog bites presenting to a medium size Canadian city’s Emergency Departments.
Methods
All adult (≥16 years) patients presenting to Emergency Departments in our region during a 30-month period (January 2013 to June 2015) were identified. Demographics, injury patterns, and dog-specific characteristics were studied.
Results
A total of 475 dog bites were identified. The greatest proportion of dog bites occurred in the summer months (140, 30%). Pit-bull type was the most frequently implicated breed (27%). The majority of patients identified were female (295, 62%). The majority of bites occurred in the hands (264 cases, 56%). Bites occurring in the head and neck accounted for 11% of all injuries. Although 50% of injuries required only washout and dressing, 15 cases (3%) required a complex primary closure. The operating room was utilized in the reconstruction of eight defects (2%). There were four (1%) tendon repairs, one (0.2%) nerve repair, and one injury requiring a skin graft (0.2%). Three patients were admitted to hospital. We identified an overall infection rate of 10%.
Conclusions
Dog bites most commonly occurred in the hands and upper extremities, and carried an infection risk of approximately 10%. Large, muscular breeds were the most frequently implicated. The effectiveness of breed-specific legislation remains unclear, but educational programs for dog owners, children, and health care workers may help decrease the number and severity of attacks.
Previous research suggests that the experience of abuse and neglect in childhood has negative implications for physical health in adulthood. Using data from the Minnesota Longitudinal Study of Risk and Adaptation (N = 115), the present research examined the predictive significance of childhood physical abuse, sexual abuse, and physical/cognitive neglect for multilevel assessments of physical health at midlife (age 37–39 years), including biomarkers of cardiometabolic risk, self-reports of quality of health, and a number of health problems. Analyses revealed that childhood physical/cognitive neglect, but not physical or sexual abuse, predicted all three health outcomes in middle adulthood, even when controlling for demographic risk factors and adult health maintenance behaviors. We discuss possible explanations for the unique significance of neglect in this study and suggest future research that could clarify previous findings regarding the differential impact of different types of abuse and neglect on adult health.