This paper provides an overview of the current status of ultrafast and ultra-intense lasers with peak powers exceeding 100 TW and examines the research activities in high-energy-density physics within China. Currently, 10 high-intensity lasers with powers over 100 TW are operational, and about 10 additional lasers are being constructed at various institutes and universities. These facilities operate either independently or are combined with one another, thereby offering substantial support for both Chinese and international research and development efforts in high-energy-density physics.

In this study, we conducted interface-capturing high-resolution simulations of a bubbly upflow in a vertical channel to investigate the bubble distribution and its interaction with surrounding turbulence, focusing on the effects of the density ratio. A bulk Reynolds number $Re_b=2300$ was used for all simulations. The influence of density ratio on vortex structures and turbulence statistics differed between the near-wall and core regions of the channel. Adding 5.43 $\%$ gas caused an increase in wall friction. By applying a generalised FIK identity to analyse wall friction, it was determined that the drag rise in the bubbly channel was mostly due to the near-wall region. Visualisation of the bubble and vortex structures showed that small bubbles near the wall induced larger magnitude of Reynolds shear stress and increased wall friction. Bubble behaviour near the wall region was similar for density ratios above 30, leading to wall friction saturation. In the core region, large deformable bubbles created wake vortices due to slip velocity between liquid and gas phases. Wake vortices help large bubbles absorb smaller bubbles and maintain their sizes. As the density ratio increased, the slip velocity increased owing to greater difference in the gravitational acceleration between liquid and gas phases, resulting in corresponding increase in wake intensity and velocity fluctuations. However, quadrant analysis showed that Q1 and Q3 events increased together with Q2 and Q4 events in the core region, cancelling out any net effect of wake vortices on Reynolds shear stress or wall friction.

Embodiment theories postulate that language processing inherently engages the sensorimotor system. This study explores the embodiment of action verbs in the second language (L2) and the effects of various L2 experiences (L2 age of acquisition, exposure, dominance, and proficiency) on L2 embodiment. Sixty-one Chinese–English bilinguals participated in two experiments judging semantic relatedness: Experiment 1 involved verb–picture pairs, while Experiment 2 focused on verb–verb pairs. Both experiments were conducted in the participants’ first language (Chinese) and second language (English), with the stimuli depicting actions performed by specific effectors (e.g., mouth, hand, and foot). Results showed that participants took longer to reject mismatched verb–picture pairs and semantic-unrelated verb–verb pairs when the actions shared the same effector (e.g., walk–run) than those involving different effectors (e.g., eat–touch). Moreover, L2 age of acquisition, exposure, and dominance correlated with the L2 embodiment effect, with L2 age of acquisition and exposure modulating this effect. This study enhances our understanding of L2 embodied semantics and illuminates the impact of multidimensional L2 experiences on embodiment.

Laser-driven inertial confinement fusion (ICF) diagnostics play a crucial role in understanding the complex physical processes governing ICF and enabling ignition. During the ICF process, the interaction between the high-power laser and ablation material leads to the formation of a plasma critical surface, which reflects a significant portion of the driving laser, reducing the efficiency of laser energy conversion into implosive kinetic energy. Effective diagnostic methods for the critical surface remain elusive. In this work, we propose a novel optical diagnostic approach to investigate the plasma critical surface. This method has been experimentally validated, providing new insights into the critical surface morphology and dynamics. This advancement represents a significant step forward in ICF diagnostic capabilities, with the potential to inform strategies for enhancing the uniformity of the driving laser and target surface, ultimately improving the efficiency of converting laser energy into implosion kinetic energy and enabling ignition.

Exercise-based cardiac rehabilitation is effective in improving cardiovascular disease risk factor management, cardiopulmonary function, and quality of life. However, the precise mechanisms underlying exercise-induced cardioprotection remain elusive. Recent studies have shed light on the beneficial functions of noncoding RNAs in either exercise or illness models, but only a limited number of noncoding RNAs have been studied in both contexts. Hence, the present study aimed to elucidate the pathophysiological implications and molecular mechanisms underlying the association among exercise, noncoding RNAs, and cardiovascular diseases. Additionally, the present study analysed the most effective and personalized exercise prescription, serving as a valuable reference for guiding the clinical implementation of cardiac rehabilitation in patients with cardiovascular diseases.

Folate metabolism is involved in the development and progression of various cancers. We investigated the association of single nucleotide polymorphisms (SNP) in folate-metabolising genes and their interactions with serum folate concentrations with overall survival (OS) and liver cancer-specific survival (LCSS) of newly diagnosed hepatocellular carcinoma (HCC) patients. We detected the genotypes of six SNP in three genes related to folate metabolism: methylenetetrahydrofolate reductase (MTHFR), 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR). Cox proportional hazard models were used to calculate multivariable-adjusted hazard ratios (HR) and 95 % CI. This analysis included 970 HCC patients with genotypes of six SNP, and 864 of them had serum folate measurements. During a median follow-up of 722 d, 393 deaths occurred, with 360 attributed to HCC. In the fully-adjusted models, the MTRR rs1801394 polymorphism was significantly associated with OS in additive (per G allele: HR = 0·84, 95 % CI: 0·71, 0·99), co-dominant (AG v. AA: HR = 0·77; 95 % CI: 0·62, 0·96) and dominant (AG + GG v. AA: HR = 0·78; 95 % CI: 0·63, 0·96) models. Carrying increasing numbers of protective alleles was linked to better LCSS (HR10–12 v. 2–6 = 0·70; 95 % CI: 0·49, 1·00) and OS (HR10–12 v. 2–6 = 0·67; 95 % CI: 0·47, 0·95). Furthermore, we observed significant interactions on both multiplicative and additive scales between serum folate levels and MTRR rs1801394 polymorphism. Carrying the variant G allele of the MTRR rs1801394 is associated with better HCC prognosis and may enhance the favourable association between higher serum folate levels and improved survival among HCC patients.

Until now the research has mainly examined visible abusive supervision, like aggression and violence, but it’s unclear how subtle forms, such as gaslighting, impact victims. Gaslighting, an emotionally and psychologically manipulative form of abuse, is an increasingly prevalent phenomenon in contemporary times. Based on the conservation of resources theory, we examined how supervisory gaslighting affects job embeddedness directly and indirectly through work motivation. We also explored how coworker support moderates the gaslighting-work motivation link. Structural equation modeling was used to assess the two-wave time-lagged data from 337 Chinese hotel employees. The results show the negative direct and indirect effects of gaslighting, and coworker support moderates the negative link between gaslighting and work motivation. Hotel organizations should exercise caution when hiring supervisors to prevent gaslighting, which can undermine employee motivation and job embeddedness. This study also recommends raising awareness among employees to speak out against supervisors’ gaslighting behavior.

Previous animal studies found beneficial effects of choline and betaine on maternal glucose metabolism during pregnancy, but few human studies explored the association between choline or betaine intake and incident gestational diabetes mellitus (GDM). We aimed to explore the correlation of dietary choline or betaine intake with GDM risk among Chinese pregnant women. A total of 168 pregnant women with GDM cases and 375 healthy controls were enrolled at the Seventh People’s Hospital in Shanghai during their GDM screening at 24–28 gestational weeks. A validated semi-quantitative FFQ was used to estimate choline and betaine consumption through face-to-face interviews. An unconditional logistic regression model was adopted to examine OR and 95 % CI. Compared with the controls, those women with GDM incidence were likely to have higher pre-pregnancy BMI, be older, have more parities and have higher plasma TAG and lower plasma HDL-cholesterol. No significant correlation was observed between the consumption of choline or betaine and incident GDM (adjusted OR (95 % CI), 0·77 (0·41, 1·43) for choline; 0·80 (0·42, 1·52) for betaine). However, there was a significant interaction between betaine intake and parity on the risk of GDM (Pfor interaction = 0·01). Among those women with no parity history, there was a significantly inverse correlation between betaine intake and GDM risk (adjusted OR (95 % CI), 0·25 (0·06, 0·81)). These findings indicated that higher dietary betaine intake during pregnancy might be considered a protective factor for GDM among Chinese women with no parity history.

A partition calculation method (PCM) for calculating the diffraction efficiency of multilayer Fresnel zone plate with high aspect ratio is proposed. In contrast to the traditional theory, PCM designs and evaluates Fresnel zone plate (FZP) considering material pairs, all zone widths, thicknesses and X-ray energy more completely. The results obtained through PCM are validated by comparing them with the complex amplitude superposition theory and coupled wave theory numerical results. The PCM satisfies the requirements of the theoretical investigation of FZP with small outermost zone width (drN) and large thickness (t). Combining proper numerical analysis with the experimental conditions will present a great potential to break through the imaging performance of X-ray microscopy.

In the context of big data, the rise of digital inclusive finance is driving the digital transformation of various industries, which in turn, has a profound impact on labour employment. Based on the panel data of 258 prefecture-level cities in China from 2011 to 2021, this article evaluates the impact of digital financial inclusion on the employment structure of the labour force and investigates its spatial spillover effects by constructing a spatial Durbin model and a mediation model. The study finds that: (1) Digital financial inclusion increases the employment demand for high-skilled and low-skilled labour and decreases the employment demand for middle-skilled labour, that is, the employment structure of the labour force shows a polarisation trend. (2) There is a positive spatial spillover effect of the impact of the development of digital financial inclusion on the demand for high- and low-skilled labour. (3) Financial digitisation plays an intermediary role in the process of digital financial inclusion affecting the employment structure of the labour force. Taking advantage of the dividends brought about by the development of digital inclusive finance and formulating policies according to the actual situation of each region indicate an undeniable choice for achieving full employment.

Enhancing seedling quality and promoting root growth post-transplantation are crucial for improving mechanically transplanted rice productivity. Here we investigated the impact of various plant growth regulators on hybrid and conventional rice varieties. Treatments, including two-diethylaminoethyl hexanoate (DA-6, 10 mg L−1), a combination of potassium 3-indole-butyrate + potassium 1-naphthylacetate + 6-benzylaminopurine (C3, 50 + 50 + 10 mg L−1), potassium 3-indole-butyrate + potassium 1-naphthylacetate + 1-triacontanol (C4, 50 + 50 + 50 mg L−1), potassium 3-indole-butyrate + potassium 1-naphthylacetate + 1.8% sodium nitrophenolate (C5, 50 + 50 + 1 mg L−1), and a combination of potassium 3-indole-butyrate + potassium 1-naphthylacetate + 1.8% sodium nitrophenolate + DA-6 (C6, 50 + 50 + 1 + 10 mg L−1), were sprayed either 3 or 10 days before transplanting. Seedlings sprayed 10 days before transplanting exhibited a higher number of white roots and total roots at the returning green stage, along with increased grain yield, irrespective of the plant growth regulator used. The C6 combination emerged as the most effective treatment, enhancing the growth of both hybrid and conventional rice seedlings, accelerating the growth rate of white roots and total roots, and increasing the length of the longest white root during the greening period, ultimately resulting in higher grain yield. Our findings demonstrate that pre-transplantation application of a combination of plant growth regulators positively influences rice seedling growth.

Accurately predicting neurosyphilis prior to a lumbar puncture (LP) is critical for the prompt management of neurosyphilis. However, a valid and reliable model for this purpose is still lacking. This study aimed to develop a nomogram for the accurate identification of neurosyphilis in patients with syphilis. The training cohort included 9,504 syphilis patients who underwent initial neurosyphilis evaluation between 2009 and 2020, while the validation cohort comprised 526 patients whose data were prospectively collected from January 2021 to September 2021. Neurosyphilis was observed in 35.8% (3,400/9,504) of the training cohort and 37.6% (198/526) of the validation cohort. The nomogram incorporated factors such as age, male gender, neurological and psychiatric symptoms, serum RPR, a mucous plaque of the larynx and nose, a history of other STD infections, and co-diabetes. The model exhibited good performance with concordance indexes of 0.84 (95% CI, 0.83–0.85) and 0.82 (95% CI, 0.78–0.86) in the training and validation cohorts, respectively, along with well-fitted calibration curves. This study developed a precise nomogram to predict neurosyphilis risk in syphilis patients, with potential implications for early detection prior to an LP.