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Brachytherapy is an effective local treatment for early-stage head and neck cancers. Mold irradiation is a method in which the source is placed in the oral cavity in sites where the soft tissue is thin and an irradiation source cannot be implanted. However, dose calculations based on TG-43 may be subject to uncertainty due to the heterogeneity of tissues and materials used for the irradiation of head and neck cancers.
Materials and Methods:
In this study, we investigated the basic physical properties of different materials and densities in the molds, retrospectively analysed patient plans and verified the doses of intraoral mold irradiation using a dose verification system with MC simulations specifically designed for brachytherapy, which was constructed independently.
Results and Discussion:
Dose–volume histograms were obtained with a treatment planning system (TG-43) and MC simulation and revealed a non-negligible difference in coverage of high-risk clinical target volume (HR-CTV) and organ at risk (OAR) between calculations using computed tomography values and those with density changes. The underdose was 10·6%, 3·7% and 5·6% for HR-CTV, gross tumour volume and OAR, respectively, relative to the treatment plan. The calculations based on the differences in the elemental composition and density changes in TG-43, a water-based calculation algorithm, resulted in clinically significant dose differences. The validation method was used only for the cases of complex small source therapy.
Conclusion:
The findings of this study can be applied to more complex cases with steeper density gradients, such as mold irradiation.
4 Nines (99.99%) Cd and Te were purified to the semiconductor grade 6 Nines ∼ 7 Nines purity materials by the distillation and the zone melting processes, in order to be used for the growth of CdTe single crystal. The CdTe single crystal of 100 mm in diameter and 18kg in weight was successfully grown by the traveling heater method (THM). The shape of the growth interface had the key role for the single crystal growth. The distribution of the Te inclusion size was measured by IR microscopy. The uniformity of mobility-lifetime products and energy resolution in the wafer were also evaluated. The CdTe X-ray flat panel detector (FPD) was developed using the THM grown CdTe single crystal wafer. The CdTe pixel detectors with 100 mm pixel pitch were flip-chip bonded with the C-MOS readout ASIC and lined up on the print circuit board to cover the active area of 77 mm × 39 mm. The evaluation results showed that the CdTe X-ray FPD is promising as the imager for the non-destructive testing.
The present authors have already reported that barium oxide is the most effective catalyst for the conversion of waste polystyrene into styrene including both monomer and dimer. Around 85 wt.% of waste polystyrene was converted into styrene when it was degraded at 623 K in the presence of barium oxide as catalyst. In this paper, the preparation and the thermal degradation of polystyrene films with dispersed catalyst are described for a design of recyclable plastics for better environment. More than 85 wt.% of the films was degraded into styrene at 623 K without addition of other catalytic compounds. Techniques for foaming the films using either nitrogen or carbon dioxide are discussed. It was found that the polystyrene foams with dispersed catalyst are well converted into styrene when they are simply degraded at 673 K.
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