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4 results

  • Association between fibroblast growth factor 19 and depressive symptoms: the moderating role of smoking

  • Siyuan Li, Lingling Chen, Mingwei Ma, Yueling Hu, Fan Wang, Xingguang Luo, Yu-Hsin Chen, Hongke Gao, Yulin Ren, Weiming Hu, Yimin Kang, Wei Wang, Li Chen, Xiaokun Li, Yanlong Liu, Junnan Wu
  • Journal:
    Acta Neuropsychiatrica / Volume 37 / 2025
    Published online by Cambridge University Press:
    14 July 2025, e74
    • Article
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      • Open access
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  • Objective:

    This study aimed to examine the relationship between fibroblast growth factor 19 (FGF19) and depressive symptoms, measured by Beck’s Depression Inventory (BDI) scores and investigate the moderating role of smoking.

    Methods:

    This study involved 156 Chinese adult males (78 smokers and 78 non-smokers) from September 2014 to January 2016. The severity of depressive symptoms was evaluated using the BDI scores. Spearman rank correlation analyses were used to investigate the relationship between cerebrospinal fluid (CSF) FGF19 levels and BDI scores. Additionally, moderation and simple slope analyses were applied to assess the moderating effect of smoking on the relationship between the two.

    Results:

    FGF19 levels were significantly associated with BDI scores across all participants (r = 0.26, p < 0.001). Smokers had higher CSF FGF19 levels and BDI scores compared to non-smokers (445.9 ± 272.7 pg/ml vs 229.6 ± 162.7 pg/ml, p < 0.001; 2.7 ± 3.0 vs 1.3 ± 2.4, p < 0.001). CSF FGF19 levels were positively associated with BDI scores in non-smokers (r = 0.27, p = 0.015), but no similar association was found among smokers (r = −0.11, p = 0.32). Linear regression revealed a positive correlation between FGF19 and BDI scores (β = 0.173, t = 2.161, 95% CI: 0.015–0.331, p < 0.05), which was negatively impacted by smoking (β = −0.873, t = −4.644, 95% CI: −1.244 to −0.501, p < 0.001).

    Conclusion:

    These results highlight the potential role of FGF19 in individuals at risk for presence of or further development of depressive symptoms and underscore the importance of considering smoking status when examining this association.

  • 15 - Managing Urban Flood Risk and Building Resilience in a Changing Climate

  • from Part III - Sustainable Water Management under Future Uncertainty
  • Edited by Qiuhong Tang, Chinese Academy of Sciences, Beijing, Guoyong Leng
  • Book:
    Climate Risk and Sustainable Water Management
    Published online:
    17 March 2022
    Print publication:
    07 April 2022, pp 315-341

  • Summary

    Urban flooding disasters have increased due to climate change in recent decades. The induced casualties and economic losses are aggravated by intense urbanization. Climate change projections present high confidence in the increase of flood hazard in the future of the twenty-first century. Moreover, population growth and socio-economic development may lead to an increase of vulnerability to flood hazard. In this context, most countries have launched relevant initiatives to mitigate and adapt to urban flooding disaster, in order to improve urban resilience to flood disaster and achieve urban sustainable development goals. Structural, semi-structural and non-structural strategies have been developed and evaluated in the framework of flood risk management. Furthermore, the integrated flood modelling framework has been developed to support the integrated flood risk assessment under a changing environment. Based on projections, urban flood resilience can be estimated and applied to improve the decision-making of flood policy and regulation, and to guide the planning and design of the flood risk management strategy. In this context, this chapter reviews and discusses the natural and anthropogenic drivers of urban flooding, flood risk management in developing and developed countries and the integrated modelling framework of flood risk management.

  • Synthesis and Characterization of Copper-Iron Nitride ThinFilms

  • Hrishikesh Kamat, Xingwu Wang, James Parry, Yueling Qin, Hao Zeng
  • Journal:
    MRS Advances / Volume 1 / Issue 3 / 2016
    Published online by Cambridge University Press:
    14 December 2015, pp. 203-208
    Print publication:
    2016

  • Iron nitride thin films have potential applications in the biomedicine andenergy. The magnetic properties of these films can be tuned by incorporatingcopper nitride. In this study, iron copper nitride thin films have beenfabricated by magnetron sputtering technique either by co-sputtering ironnitride and copper nitride or by layer stacking of the materials. The structure,morphology and magnetic properties of the films have been studied by scanningelectron microscopy, x-ray diffraction, x-ray reflectivity and vibrating samplemagnetometry.

  • Linear laser plasma toward large-sized uniform soft X-ray source

  • Xiaofang Wang, Zhizhan Xu, Shisheng Chen, Aidi Qian, Yueling Li, Pinzhong Fan, Lihuang Lin
  • Journal:
    Laser and Particle Beams / Volume 10 / Issue 4 / December 1992
    Published online by Cambridge University Press:
    09 March 2009, pp. 777-786

  • The effect of laser intensity distribution along the line focus on the uniformity of the line-shaped plasmas produced is investigated with time-integrated and time-resolved soft X-ray and optical diagnostics. Evident plasma condition nonuniformities along the line focus resulting from nonuniform laser intensity distributions have been observed with a conventional simple line-focusing technique. With a new line-focusing technique producing a uniform laser illumination, a uniform, line-shaped plasma can be obtained. It is also found that nonuniformities under uniform laser illumination occur mostly during laser heating. The line-shaped uniform laser plasma can be used as a large, uniform X-ray source besides its importance in X-ray laser demonstration and amplification. As an application of such line-shaped plasmas as X-ray sources, the no-overcoat 5F X-ray film is calibrated for the first time by a new method in the soft X-ray range from 10–80 A.