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In this work, the Riemann–Hilbert (RH) problem is employed to study the multiple high-order pole solutions of the cubic Camassa–Holm (cCH) equation with the term characterizing the effect of linear dispersion under zero boundary conditions and nonzero boundary conditions. Under the reflectionless situation, we generalize the residue theorem and obtain the multiple high-order pole solutions of cCH equation by solving an algebraic system. During the process of establishing the solution of RH problem, to simplify the calculations involving the implicitly expressed of variables (x, t) in the solution, we introduce a new scale (y, t) to ensure the solution of RH problem is explicitly expressed with respect to it. Finally, the exact solutions are obtained for cases involving one high-order pole and N high-order poles.
As a member of the Scathophagidae family, Scathophaga stercoraria (S. stercoraria) is widely distributed globally and is closely associated with animal feces. It is also a species of great interest to many scientific studies. However, its phylogenetic relationships are poorly understood. In this study, S. stercoraria was found in plateau pikas for the first time. The potential cause of its presence in the plateau pikas was discussed and it was speculated that the presence of S. stercoraria was related to the yak feces. In addition, 2 nuclear genes (18SrDNA and 28SrDNA), 1 mitochondrial gene (COI), and the complete mitochondrial genome of S. stercoraria were sequenced. Phylogenetic trees constructed based on 13 Protein coding genes (13PCGs), 18S and 28S rDNA showed that S. stercoraria is closely related to the Calliphoridae family; phylogenetic results based on COI suggest that within the family Scathophagidae, S. stercoraria is more closely related to the genus Leptopa, Micropselapha, Parallelomma and Americina. Divergence times estimated using the COI gene suggest that the divergence formation of the genus Scathophaga is closely related to changes in biogeographic scenarios and potentially driven by a combination of uplift of the Qinghai-Tibetan Plateau (QTP) and dramatic climate changes. These results provide valuable information for further studies on the phylogeny and differentiation of the Scathophaga genus in the future.
Nontuberculous mycobacteria (NTM) is a large group of mycobacteria other than the Mycobacterium tuberculosis complex and Mycobacterium leprae. Epidemiological investigations have found that the incidence of NTM infections is increasing in China, and it is naturally resistant to many antibiotics. Therefore, studies of NTM species in clinical isolates are useful for understanding the epidemiology of NTM infections. The present study aimed to investigate the incidence of NTM infections and types of NTM species. Of the 420 samples collected, 285 were positive for M. tuberculosis, 62 samples were negative, and the remaining 73 samples contained NTM, including 35 (8.3%) only NTM and 38 (9%) mixed (M. tuberculosis and NTM). The most prevalent NTM species were Mycobacterium intracellulare (30.1%), followed by Mycobacterium abscessus (15%) and M. triviale (12%). M. gordonae infection was detected in 9.5% of total NTM-positive cases. Moreover, this study reports the presence of Mycobacterium nonchromogenicum infection and a high prevalence of M. triviale for the first time in Henan. M. intracellulare is the most prevalent, accompanied by some emerging NTM species, including M. nonchromogenicum and a high prevalence of M. triviale in Henan Province. Monitoring NTM transmission and epidemiology could enhance mycobacteriosis management in future.
A new species of Moniliformis, M. tupaia n. sp. is described using integrated morphological methods (light and scanning electron microscopy) and molecular techniques (sequencing and analysing the nuclear 18S, ITS, 28S regions and mitochondrial cox1 and cox2 genes), based on specimens collected from the intestine of the northern tree shrew Tupaia belangeri chinensis Anderson (Scandentia: Tupaiidae) in China. Phylogenetic analyses show that M. tupaia n. sp. is a sister to M. moniliformis in the genus Moniliformis, and also challenge the systematic status of Nephridiacanthus major. Moniliformis tupaia n. sp. represents the third Moniliformis species reported from China.
Soil aggregates consist of sand, silt, and clay size particles. Many of the clay size particles in soils are clay minerals, which actively influence soil behavior. The properties of clay minerals may change significantly as soil particle size decreases to the nanoscale; however, little information is available about these properties for the Ultisols in China. In the present study, the clay mineral components and structural characteristics of four particle-size fractions (i.e., <2000, 450–2000, 100–450, and 25–100 nm) of two Ultisol samples (Ult-1 and Ult-2) were investigated using elemental analysis, X-ray diffraction, Fouriertransform infrared spectroscopy, and thermal analysis. The molar SiO2 to Al2O3 ratios were lower in the nanoscale particle-size fraction (25–100 nm) than in the 450–2000 and <2000 nm fractions. This indicates greater desilicification and allitization of the smaller Ultisol particles. Furthermore, the Fe oxide and Al oxide contents increased and reached a maximum level in the 25–100 nm fraction of the two Ultisols. Goethite was mainly found in the 100–450 nm and 25–100 nm fractions. The dominant clay minerals in the Ultisol 25–100 nm fraction were kaolinite and illite with a small amount of a hydroxy-interlayered mineral in Ult-1 and gibbsite in Ult-2. The kaolinite crystallinity decreased as particle size decreased. The low crystallinity of the kaolinite in the A horizon 25–100 nm fraction was attributed to a reduction in the thickness of coherent scattering domains, as well as to decreases in OH groups and the dimensions of octahedral AlO6 sheets. A determination of the chemical and mineralogic properties of the different size fractions of the Ultisols is important to understand the desilicification and Al and Fe oxide enrichment mechanisms during soil formation. The significance of these results can help to reveal the nanoscale transformations of clay minerals. Analysis of clay mineral compositions in nanoparticles can provide the additional data needed to understand the adsorption and mobility of nutrients and pollutants.
This study aimed to investigate the characteristics and prognosis of patients with alcoholic Marchiafava–Bignami disease (MBD), a rare neurological disorder commonly associated with chronic alcoholism, in Chongqing, China.
Methods:
We conducted a retrospective analysis of clinical data from 21 alcoholic MBD patients treated at the First Affiliated Hospital of Chongqing University between 2012 and 2022.
Results:
The study included 21 patients with alcoholic MBD who had a mean age of 59 ± 9.86 years and an average drinking history of 35.48 ± 8.65 years. Acute onset was observed in 14 (66.7%) patients. The primary clinical signs observed were psychiatric disorders (66.7%), altered consciousness (61.9%), cognitive disorders (61.9%), and seizures (42.9%). Magnetic resonance imaging revealed long T1 and long T2 signal changes in the corpus callosum, with lesions predominantly found in the genu (76.2%) and splenium (71.4%) of the corpus callosum. The poor prognosis group demonstrated an increased incidence of altered consciousness (100% vs 50%, P = 0.044), pyramidal signs (80% vs 18.8%, P = 0.011), and pneumonia (100% vs 31.3%, P = 0.007). Patients with a longer drinking history (45.0 ± 10.0 years vs 32.69 ± 5.99 years, p = 0.008) and a lower thiamine dose (p = 0.035) had a poorer prognosis at 1 year.
Conclusions:
This study identified altered consciousness, pyramidal signs, and pneumonia as predictors of a poor prognosis in patients with alcoholic MBD. A longer duration of alcohol consumption and inadequate thiamine supplementation were associated with a poorer prognosis.
Wave radiation and diffraction problems of a body floating in an open water channel confined by two semi-infinite ice sheets are considered. The linearized velocity potential theory is used for fluid flow and a thin elastic plate model is adopted for the ice sheet. The Green function, which satisfies all the boundary conditions apart from that on the body surface, is first derived. This is obtained through applying Fourier transform in the longitudinal direction of the channel, and matched eigenfunction expansions in the transverse plane. With the help of the derived Green function, the boundary integral equation of the potential is derived and it is shown that the integrations over all other boundaries, including the bottom of the fluid, free surface, ice sheet, ice edge as well as far field will be zero, and only the body surface has to be retained. This allows the problem to be solved through discretization of the body surface only. Detailed results for hydrodynamic forces are provided, which are generally highly oscillatory owing to complex wave–body–channel interaction and body–body interaction. In depth investigations are made for the waves confined in a channel, which does not decay at infinity. Through this, a detailed analysis is presented on how the wave generated by a body will affect the other bodies even when they are far apart.
Flexural-gravity wave interactions with multiple cracks in an ice sheet of infinite extent are considered, based on the linearized velocity potential theory for fluid flow and thin elastic plate model for an ice sheet. Both the shape and location of the cracks can be arbitrary, while an individual crack can be either open or closed. Free edge conditions are imposed at the crack. For open cracks, zero corner force conditions are further applied at the crack tips. The solution procedure starts from series expansion in the vertical direction based on separation of variables, which decomposes the three-dimensional problem into an infinite number of coupled two-dimensional problems in the horizontal plane. For each two-dimensional problem, an integral equation is derived along the cracks, with the jumps of displacement and slope of the ice sheet as unknowns in the integrand. By extending the crack in the vertical direction into the fluid domain, an artificial vertical surface is formed, on which an orthogonal inner product is adopted for the vertical modes. Through this, the edge conditions at the cracks are satisfied, together with continuous conditions of pressure and velocity on the vertical surface. The integral differential equations are solved numerically through the boundary element method together with the finite difference scheme for the derivatives along the crack. Extensive results are provided and analysed for cracks with various shapes and locations, including the jumps of displacement and slope, diffraction wave coefficient, and the scattered cross-section.
The microbiota–gut–brain axis, especially the microbial tryptophan (Trp) biosynthesis and metabolism pathway (MiTBamp), may play a critical role in the pathogenesis of major depressive disorder (MDD). However, studies on the MiTBamp in MDD are lacking. The aim of the present study was to analyze the gut microbiota composition and the MiTBamp in MDD patients.
Methods
We performed shotgun metagenomic sequencing of stool samples from 26 MDD patients and 29 healthy controls (HCs). In addition to the microbiota community and the MiTBamp analyses, we also built a classification based on the Random Forests (RF) and Boruta algorithm to identify the gut microbiota as biomarkers for MDD.
Results
The Bacteroidetes abundance was strongly reduced whereas that of Actinobacteria was significantly increased in the MDD patients compared with the abundance in the HCs. Most noteworthy, the MDD patients had increased levels of Bifidobacterium, which is commonly used as a probiotic. Four Kyoto Encyclopedia of Genes and Genomes (KEGG) orthologies (KOs) (K01817, K11358, K01626, K01667) abundances in the MiTBamp were significantly lower in the MDD group. Furthermore, we found a negative correlation between the K01626 abundance and the HAMD scores in the MDD group. Finally, RF classification at the genus level can achieve an area under the receiver operating characteristic curve of 0.890.
Conclusions
The present findings enabled a better understanding of the changes in gut microbiota and the related Trp pathway in MDD. Alterations of the gut microbiota may have the potential as biomarkers for distinguishing MDD patients form HCs.
Wave radiation and diffraction by a circular cylinder submerged below an ice sheet with a crack are considered based on the linearized velocity potential theory together with multipole expansion. The solution starts from the potential due to a single source, or the Green function satisfying both the ice sheet condition and the crack condition, as well as all other conditions apart from that on the body surface. This is obtained in an integral form through Fourier transform, in contrast to what has been obtained previously in which the Green function is in the series form based on the method of matched eigenfunction expansion in each domain on both sides of the crack. The multipole expansion is then constructed through direct differentiation of the Green function with respect to the source position, rather than treating each multipole as a separate problem. The use of the Green function enables the problem of wave diffraction by the crack in the absence of the body to be solved directly. For the circular cylinder, wave radiation and diffraction problems are solved by applying the body surface boundary condition to the multipole expansion, through which the unknown coefficients are obtained. Extensive results are provided for the added mass and damping coefficient as well as the exciting force. When the cylinder is away from the crack, a wide spacing approximation method is used, which is found to provide accurate results apart from when the cylinder is quite close to the crack.
In traditional antenna design, metal components are not placed in the central part of the antenna as they change the characteristics of near field radiation. However, we show that placing a metal ring in the centre of the strip lines, which connect the ends of folded high-frequency dipoles, does not damage the performance of the feed. Instead it significantly improves the voltage standing wave ratio of the feed whilst other performance indicators are not compromised. Thus, our findings show an excellent way of improving the wide band feed. Based on this foundation, a new circularly polarised feed for operation between 0.4 to 2 GHz is introduced for the Chinese Spectral Radioheliograph in this paper. The issue of a feed impedance matching network is investigated. By optimising the impedance matching, the performance of the feed is enhanced with respect to the previous realisations of the Eleven feed. The simulation and experimental results show that the gain of the feed is about 10 dBi, and the VSWR is less than 2:1. In addition, the feed has a low axial ratio, fixed phase centre location, and constant beam width in the range of 0.4 to 2 GHz.
The Chinese Spectral Radioheliograph is an aperture-synthesis telescope observing the Sun in ultra wide bandwidth on the ground. It contains two arrays Chinese Spectral Radioheliograph-I and Chinese Spectral Radioheliograph-II from 0.4 to 15 GHz. In order to obtain ultra wide-band performance, the cascaded folded dipoles are used in this feed. At the same time, in order to get circularly polarised signals coming from the Sun, a wide-band 90° hybrid is added in the output ports of the feed. This feed has characteristics of about 10 dBi gain, less than 1.5 voltage standing wave ratio. It also has characteristics with low axial ratio, fixed phase centre location, and constant beam width in operating frequencies. Through cross-correlating all combinations of two orthogonal polarisations at each antenna, the polarisation state of the waves is measured and give a differential instrumental delay between two data channels. The relationship between the own polarisation degree of the Sun and the observed polarisation degree is also measured for cross-polarised delay in observing the Sun in this paper.
Low-temperature stress is an important limiting factor to tobacco growth in early spring of south China. In this study, a low-temperature-resistant agent (LTRA) was employed to examine its ameliorating effect on the inhibition of tobacco growth triggered by low-temperature stress. Results indicated that low-temperature stress of 12 °C for 6 days reduced root number and biomass of tobacco seedling by 27.4% and 24.1%, while treatment with LTRA could recover the inhibitory effect of low-temperature stress on tobacco growth significantly. The content of ascorbic acid and the activities of superoxide dismutase and catalase at low-temperature stress were 65.2%, 53.5% and 32.1% of those at normal temperature condition (26 °C), while the corresponding values with LTRA treatment were 89.2%, 88.9% and 74.2%, suggesting that LTRA treatment could enhance the activity of antioxidant enzyme and the synthesis of antioxidant compounds. Low-temperature stress increased the membrane permeability by 84.8%, while LTRA treatment recovered it by 77.4%. Furthermore, LTRA treatment contributed to increase chlorophyll synthesis and maintain the integrity of tobacco leaf structure. Effective component analysis indicated that the complex of ammonium calcium nitrate and glycine betaine was the main effective component of LTRA in maintaining membrane integrity. Its effective concentration was 1.0 g L−1. The above results suggested that LTRA could enhance the synthesis of chlorophyll, activate the activity of antioxidant enzyme, maintain the integrity of cell membrane, and thus elevate the tolerance of tobacco seedlings to low-temperature stress.
To investigate the influence of pulse repetition rate on the average
size of the nanoparticles, nanocrystalline Si films were prepared by
pulsed laser ablation in high-purity Ar gas with a pressure of 10 Pa at
room temperature, under the pulse repetition rates between 1 and 40 Hz,
using a nanosecond laser. Raman, X-ray diffraction spectra, and scanning
electron microscopy images show that with increasing pulse repetition
rate, the average size of the nanoparticles in the film first decreases
and reach its minimum at 20 Hz, and then increases, which may be
attributed to the nonlinear dynamics of the laser-ablative deposition. In
our experiment conditions, the duration of the ambient restoration, a
characteristic parameter being used to distinguish nonlinear or linear
region, is about a few seconds from the order of magnitude, which is
consistent with the previous experimental observation. More detailed model
to explain quantitively the observed effect is under investigation.
In order to assess the influence of nutrient elements on the accumulation of β-N-oxalyl-L-α, β-diaminopropionic acid (β-ODAP; the probable cause of lathyrism) in Lathyrus sativus L. (grass pea), it was first examined under field conditions during the lifespan of a grass pea plant using high-performance liquid chromatography (HPLC). β-ODAP mainly accumulated in young seedlings, in developing and mature seeds and in young leaves, especially in young seedlings. In contrast, all mature leaves, roots, and stems showed a low level of β-ODAP. The β-ODAP accumulation pattern in seedlings grown in a nutrient-deficient solution was highest (3·57 mg/g) in shoots at 7 d growing in the nitrogen-deficient solution and higher compared to the control (2·31 mg/g) in zinc-, calcium-, phosphorus- and molybdenum-deficient shoots (P<0·05). The contents of β-ODAP in seedlings growing in other element-deficient solutions were similar to controls. When the content of β-ODAP in grass pea seedlings fertilized with different forms of organic nitrogen was assayed the results indicated that amino acids such as glutamine and serine, as well as nucleotide nitrogen, all significantly enhanced the accumulation of β-ODAP in young seedlings relative to controls (P<0·05). Taken together, these data suggest that β-ODAP accumulation in grass pea might be related to the level of total free nitrogenous compounds and that nitrogen and phosphate may be the crucial nutrient factors influencing β-ODAP content under field conditions. Thus, the application of appropriate nitrogen and phosphorus fertilizers to the soil could decrease the content of β-ODAP in the seeds and leaves of grass pea.
Covalent carbon nitride films have been synthesized by laser ablation and ion-beam coprocessing. Different laser ablations give different ablated graphite plasma. Beta- C3N4 polycrystalline has been found in the deposited films. Under laser energy of 50 mJ per pulse, the adoption of 532 nm laser used for ablation of graphite is proposed for the purpose of production of good carbon nitride films. The C-N crystal structures can be improved by followed ion-beam processing.
C50 films, are deposited on Si(111) substrates using neutral cluster beams of fullerenes generated from a crucible with a special nozzle. X-ray diffraction (XRD) have been used to investigate the structural properties of C50 films, which indicate highly textural films as close-packed structure with strong (110) XRD assignment and 400Å for correlation length. Raman spectrum indicates the existence of stable C60 films. X-ray photoelectron spectroscopy (XPS) and Auger electron spectroscopy (AES) measurements are carried out to analyze the electronic properties of the films. The resistivity to contamination of C50 film deposited here is better than that deposited by MBE. Different kinds of oxygen contamination on the surfaces of C50 films and HDPG are detected by the results of O 1s XPS analyses.
C60 films have been deposited using a partially ionized cluster beam deposition (PIBD) technique. The experimental results show that as Va. exceeds about 400 V almost all the C60 molecules fragmentate at collision with the substrate and the obtained films turn to be amorphous carbon layers at elevated Va, indicated by measurements of Raman spectra, X-ray diffraction, and ellipsometry.
Ionized cluster beam deposition (ICBD) technique has been used to deposit Ag films on both Si(111) and Si(100) substrates. Sizes of clusters in ionized cluster beam are found to distribute in a range of 100–600 atoms/cluster. X-ray diffraction (XRD), and α-step profile methods are used to analyze the properties of Ag films. As a comparison, Ag films deposited by conventional evaporation are also investigated. Highly textured Ag films with strong (111) orientation on Si (111) have been obtained at high accelerating voltage Va=4kV. The crystallinity and surface flatness of Ag films can be improved by ICBD at high accelerating voltages.