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Perinatal mental health disorders affect more than one in five people and obstetrician/gynecologists (Ob/Gyns) are the primary providers for women during the reproductive years when there is increased risk of psychiatric morbidity. Therefore, Ob/Gyns are charged with screening and treating these disorders. Despite the availability of effective strategies for detection and treatment, perinatal mental health disorders are underrecognized and undertreated, and have significant detrimental maternal and infant consequences. Obstetrician/gynecologists should be prepared to counsel patients on the benefits and risks of psycho-pharmacotherapy, initiate psycho-pharmacotherapy, and refer patients to appropriate resources when indicated. A validated screening tool should then be used to monitor for response to treatment or remission of symptoms. Psychotherapy should be considered a first-line treatment for mild-to-moderate perinatal depression and selective serotonin reuptake inhibitors be used as first-line pharmacotherapy for perinatal depression and anxiety. Pharmacotherapy should be individualized based on prior response to therapy and optimal dosing established to avoid undertreatment. The risks associated with inadequately treated mental health conditions as well as the perinatal risks associated with psychopharmacologic agents must be addressed. Furthermore, a discussion about duration of treatment, need for long term follow-up, and considerations for future pregnancy is needed.
This study exploratively analyzed the associations of well-being with psychological characteristics, socioeconomic status (SES), and the number of relocations after the Fukushima nuclear disaster.
Methods
Using a cross-sectional study design, an online questionnaire survey was administered to 416 residents of Fukushima and Tokyo each aged 20-59 years (832 in total) between August 25 and 26, 2018, which was 7 and a half years after the disaster. Categorical factor analysis and multiple regression analysis were performed to investigate associations of 5 well-being scales (positive emotion, negative-free emotion, life satisfaction and general happiness, positive characteristics, and positive functioning) with psychological characteristics, SES, and the number of relocations.
Results
Four of the well-being scales, except for negative-free emotion, were strongly associated with each other and showed similarities in the strength of their associations with psychological characteristics and SES. Among the items surveyed, psychological distress, mindfulness, and marital status were strongly associated with well-being among Fukushima residents. Contrarily, radiation risk perception or the number of relocations were not significantly associated with well-being.
Conclusions
Focusing on psychological distress is expected to have a significant impact on improving well-being after the disaster. In addition, assistance in avoiding unintended family separation may be helpful.
Childhood bereavement is a public health issue with significant mental health implications, including depression, intrusive grief, and suicidality. Theories suggest that children’s malleable processes, like coping and subjective views of themselves and their environment, influence adaptation to bereavement. Protective processes may mitigate mental health risks, while risk processes may exacerbate them. Using a sample of support-seeking, parentally-bereaved children (8–16 years; M = 11.39, SD = 2.43; 53% male; 67% White), this study employs latent profile analysis to identify baseline patterns of coping and subjective views; and examines how profile membership predicts depression symptoms, intrusive grief, and suicidality at 14-month and six-year assessments. Three profiles were identified: Low Protective-High Risk (34%), High Protective-Low Risk (23%), and High Protective-High Risk (43%). Profile membership predicted depression symptoms. Children in the Low Protective-High Risk profile showed higher depression symptoms than those in the other profiles 14-months later, while children in the High Protective-Low Risk profile unexpectedly showed higher depression symptoms six-years later compared to those in the Low Protective-High Risk profile. Profile membership did not predict intrusive grief or suicidality. Findings underscore the importance of person-centered approaches in understanding adaptation following parental death and raise questions about the association between baseline childhood protective processes and long-term depression symptoms.
Recent changes in US government priorities have serious negative implications for science that will compromise the integrity of mental health research, which focuses on vulnerable populations. Therefore, as editors of mental science journals and custodians of the academic record, we confirm with conviction our collective commitment to communicating the truth.
Regardless of any socially held perceptions of privilege or power differentials, boys and men present unique developmental vulnerabilities and disproportionate rates of specific mental health problems, such as disruptive behaviour disorders, substance misuse and completed suicide. Moreover, men are less likely than women to seek help for psychological distress and adhere less well to treatments. In this brief article, some of the unique mental health problems experienced by boys and men are reviewed within a developmental perspective and general clinical guidance is outlined to improve adherence and treatment outcomes.
Fluvial flooding is a recurring event in the Aie River basin in Assam, India. On August 14, 2021, floodwater breached a large stretch of embankment in the Bongaigaon District and inundated several villages. Using a cross-sectional design to conduct household surveys in February and March 2022, the study investigates responses six to seven months following the August 2021 flood disasters. The purpose of this study is to determine the prevalence and risk factors of four psychological health outcomes. Being flooded is strongly and adversely associated with each of these mental health outcomes. After adjusting for the potential confounders, the strength of the relationships is reduced to four times (adjusted OR 4.62 [95% CI 2.63–8.1]; p < 0.01) for PTSD, five times (adjusted OR 5.28[95% CI 3.38–8.26]; p < 0.01) for anxiety, and three times (adjusted OR 3.45[95% CI 2.24–5.33]; p < 0.01) for depression, and 21 times for comorbid PTSD, anxiety, and depression (adjusted OR 21.68[95% CI 7.38–63.74]; p < 0.01). The robustness of flood exposure is checked in an extended model. It includes variables that indicate the severity of flooding and various secondary stressors. The present study also explores the effects of ‘loss stressors’ such as crop loss, workday loss, livestock loss, and damage to infrastructure. Located in a resource-constrained setting, the effects of these factors add value to the study. Longer duration of floodwater in the house premise increases the odds of developing anxiety (adjusted OR 1.69[95% CI 1.04–2.75]; p < 0.05) and depression (adjusted OR 1.9[95% CI 1.15–3.12]; p < 0.05). Similarly, deeper floodwater inside the house increases the odds of depression (adjusted OR 1.87[95% CI 1.07–3.28]; p < 0.05). Among all the ‘loss’ stressors, damage to houses and the cost of repairing is significantly associated with PTSD (adjusted OR 2.04[95% CI 1.09–3.82]; p < 0.05), depression (adjusted OR 2.17[95% CI 1.22–3.87]; p < 0.01) and comorbid PTSD, anxiety and depression (adjusted OR 2.16[95% CI 1.07–4.36]; p < 0.05).
Unhealthy lifestyle behaviors are prevalent among people with mental illness (MI), affecting their physical and mental health. Most research has focused on the isolated effects of lifestyle behaviors, leaving the interconnectedness between these behaviors and health outcomes unexplored. This study aimed to examine these relationships and identify the most strongly connected lifestyle behavior or health outcome within a network.
Methods
We conducted a cross-sectional study with 423 inpatients with MI, receiving care as usual. Lifestyle behaviors, physical and mental health outcomes were assessed through questionnaires and routine data. A Gaussian Graphical Model was estimated, and strength centrality was calculated to identify the most influential nodes.
Results
Mean age was 55.5 years, 42% were female, and 41% were diagnosed with schizophrenia. Psychological and physical quality of life (QoL), nighttime sleep problems, and overall sleep quality were the most strongly connected nodes. Sleep was strongly associated with physical QoL. Furthermore, there were negative associations between healthy food intake and cholesterol ratio, and positive associations between daily doses of antipsychotics and length of hospital stay. Node strength was stable (CS(cor = 0.7) = 0.75). No clear pattern emerged among other lifestyle behaviors and health outcomes.
Conclusions
This study offers insights into the interrelatedness of lifestyle behaviors and health outcomes. Addressing sleep problems could enhance QoL and potentially influence other health outcomes. Psychological and physical QoL were also strongly associated, emphasizing the importance of perceived well-being in health outcomes. Future research could explore causal pathways to identify treatment targets to improve care.
The COVID-19 pandemic significantly challenged the mental health of children and adolescents, with existing research highlighting the negative effects of restrictive measures to control the virus’s spread. However, in the specific context of this pandemic, there is limited understanding of how these difficulties have persisted over time after the situation was fully restored. This study sought to evaluate the pandemic’s impact on psychological symptoms in children from Italy, Spain, and Portugal across five-time points (2, 5, and 8 weeks, 6 months, and three and a half years after the pandemic’s onset). A total of 1613 parents completed the Psychological Impact of COVID-19 and Confinement on Children and Adolescents Scale, reporting symptoms in their children aged 3–17 years (39.2% female). The findings reveal an initial surge in psychological difficulties—anxiety, mood, sleep, behavioral, eating, and cognitive disturbances—followed by improvements in these domains three and a half years later. By September 2023, Spanish children experienced more significant reductions in symptoms compared to their Italian and Portuguese peers. While the COVID-19 pandemic has been a prolonged crisis, with varying impacts over time and across regions depending on the strictness of restrictions, the trends suggest a gradual improvement in the psychological well-being of children and adolescents.
There has been an increasing number of applications from unaccompanied asylum-seeking children (UASC) in the United Kingdom in recent years. It is well-known that this population is at high-risk of developing mental health disorders, which require early detection and intervention to facilitate successful integration. This paper describes the introduction of mental health screening for unaccompanied asylum-seeking children in a National Health Service (NHS) outpatient clinic in central London. This follows the results of a two-year retrospective analysis of the health needs of the population in our clinic, which identified a high incidence of disturbance to mood and sleep. We describe the selection process for a culturally appropriate and validated screening tool, piloting the Refugee Health Screener (RHS) tool with 20 UASC in clinic, and using preliminary findings to inform a more targeted referral to community Child and Adolescent Mental Health Services (CAMHS). We conclude that implementation of the RHS-13 is feasible for widespread mental health screening for UASC in an NHS setting, and provide suggestions for future research directions within this field.
There are 117.3 million people forcibly displaced because of war, conflict and natural disasters: 40% are children. With growing numbers, many high-income countries have adopted or are considering increasingly restrictive policies of immigration detention. Research on the impact of detention on mental health has focused on adults, although recent studies report on children.
Aims
To synthesise data on the impact of immigration detention on children’s mental health.
Method
Systematic searches were conducted in PsycINFO, MEDLINE and Embase databases and grey literature and studies assessed using PRISMA guidelines (PROSPERO registration CRD42023369680). Included studies were quantitative, assessed children younger than 18 years who had been in immigration detention and reported mental health symptoms or diagnoses. Methodological quality was assessed using the Appraisal Tool for Cross-Sectional Studies. Meta-analyses estimated prevalence for major depression and post-traumatic stress disorder (PTSD).
Results
Twenty-one studies reported data on 9620 children. Most studies were cross-sectional, had small sample sizes and used convenience sampling. A profoundly detrimental impact on children’s mental health across a variety of countries and detention settings was demonstrated. Meta-analysis found pooled prevalence of 42.2% for depression [95% CI 22.9, 64.3] and 32.0% for PTSD [95% CI 19.4, 48.0]. Severity of mental health impact increased with exposure to indefinite or protracted held detention.
Conclusions
Immigration detention harms children. No period of detention can be deemed safe, as all immigration detention is associated with adverse impacts on mental health. Our review highlights the urgency of alternative immigration policies that end the practice of detaining children and families.
Autistic people have high levels of mental ill-health and an increased risk of suicide across the lifespan. Yet autistic people report difficulties communicating with healthcare professionals and accessing a range of healthcare services. At the same time, mental healthcare workers in other countries are reporting links between confidence when working with autistic patients and the degree of autism knowledge and training they can access.
Methods:
We sought to examine what factors helped or hindered Irish mental healthcare colleagues when working with autistic healthcare service users. An online survey using quantitative and qualitative metrics was circulated among psychiatrists who are members of the College of Psychiatrists of Ireland, both in training and at consultant level, from April 2021 to April 2022.
Results:
Knowledge of autism was high among psychiatrists (n = 140), but self-efficacy scores were variable, particularly in relation to care pathways. Self-efficacy was better among psychiatrists with caseloads of children and youth or individuals with co-occurring intellectual disabilities. Three key qualitative themes emerged relating to capacity and training of mental health professionals, ways to improve mental health services provision for autistic individuals and also the critical need for co-creation and neurodiversity affirmative care.
Conclusions:
The study highlighted critical systemic and professional challenges in providing mental health care to autistic people in Ireland. We provide recommendations for reducing these challenges and for enabling the development of inclusive, evidenced-based care to autistic individuals.
This study aims to discern similarities and differences associated with the impact of war on Ukrainian and Israeli women. We hypothesize that country affiliation significantly determines their mental health and psycho-emotional well-being. A total of 1,071 Ukrainian (N = 601) and Israeli (N = 470) women were surveyed online from September to December 2022 in Ukraine and November 2023 to March 2024 in Israel. Valid and reliable survey instruments were used to gather data about the fear of war, depression, loneliness, suicidal ideation and substance misuse. Fear of war and depression were higher among Israeli respondents. However, Ukrainian women reported more loneliness, substance use and psycho-emotional deterioration. Respondents from both countries did not show a different level of suicidal ideation. Two-way analysis of variance (ANOVA) results show fear of war associated with country and depression; and depression linked to country and increased alcohol use, especially among Ukrainian respondents. Comparative results partially confirm the study hypothesis. The impact of the war on Ukrainian and Israeli women has similar effects; however, differences exist that may be attributed to culture and adaptation to war length. Further research, including uniform data collection and analysis, is needed to determine the impact of war on women as well as their familial and work-related responsibilities that tend to increase during such conditions.
Preexisting epidemiological studies suggest that early pubertal development in males is associated with externalizing (e.g. conduct problems, risky behavior, and aggression) and internalizing (e.g. depression and anxiety) traits and disorders. However, due to problems inherent to observational studies, especially of residual confounding, it remains unclear whether these associations are causal. Mendelian randomization (MR) studies take advantage of the random allocation of genes at conception and can establish causal relationships.
Methods
In this study, N = 76 independent genetic variants for male puberty timing (MPT) were derived from a large genome-wide association study (GWAS) on 205,354 participants and used as an instrumental variable in MR studies on 17 externalizing and internalizing traits and psychopathologies utilizing outcome GWAS with 16,400–1,045,957 participants.
Results
In these MR studies, earlier MPT was significantly associated with higher scores for the overarching phenotype of ‘Externalizing Traits’ (b = −0.03, 95% CI [−0.06, −0.01]). However, this effect was likely driven by an earlier age at first sexual contact (b = −0.17, 95% CI [−0.21, −0.13]), without evidence for an effect on further externalizing phenotypes. Regarding internalizing phenotypes, earlier MPT was associated with higher levels of the ‘Depressed Affect’ subdomain of neuroticism (b = −0.04, 95% CI [−0.07, −0.01]). Late MPT was related to higher scores of internalizing traits in early life (b = 0.04, 95% CI [0.01, 0.08]).
Conclusions
This comprehensive MR study supports a causal effect of MPT on specific traits and behaviors. However, no evidence for an effect of MPT on long-term clinical outcomes (depression, anxiety disorders, alcohol dependency, cannabis abuse) was found.
Care planning for recovery and to work towards hospital discharge is integral to good practice in mental health in-patient settings. Authorised leave from hospital, especially for those who are detained, can be used to check readiness for discharge and to maintain social connections that support a patient’s recovery journey. Leave therefore often involves friends and family, or ‘carers’. However, carer involvement in planning leave is limited, and carers struggle with feeling unsupported during the leave.
Aims
This study aimed to explore carers’ and mental health practitioners’ subjective experiences of leave in the context of implementing a set of practice guidelines for involving carers in planning and undertaking leave from hospital.
Method
Nine wards in six National Health Service trusts were recruited to implement the guidelines. Interviews were undertaken with carers (n = 6) and practitioners (n = 3) from these implementation wards and with carers (n = 7) from nine usual care wards. A further ten practitioners completed an anonymous online survey. Data were analysed thematically.
Results
Carers’ experiences on both implementation and usual care wards indicated variable levels of involvement, with carers positioned as partners in care, observers of care or outsiders to care. Practitioner perspectives highlighted practical, structural and conceptual challenges in working with carers, which precluded effective implementation of the guidelines.
Conclusions
The guidelines reflected what both carers and practitioners described as good practice, but resource limitations, unclear responsibilities and perceptions of carer roles limited engagement. Implementing approaches to working with carers in in-patient settings requires resourcing and clear role definition within staff–carer relationships.
Developing integrated mental health services focused on the needs of children and young people is a key policy goal in England. The THRIVE Framework and its implementation programme, i-THRIVE, are widely used in England. This study examines experiences of staff using i-THRIVE, estimates its effectiveness, and assesses how local system working relationships influence programme success.
Methods
This evaluation uses a quasi-experimental design (10 implementation and 10 comparison sites.) Measurements included staff surveys and assessment of ‘THRIVE-like’ features of each site. Additional site-level characteristics were collected from health system reports. The effect of i-THRIVE was evaluated using a four-group propensity-score-weighted difference-in-differences model; the moderating effect of system working relationships was evaluated with a difference-in-difference-in-differences model.
Results
Implementation site staff were more likely to report using THRIVE and more knowledgeable of THRIVE principles than comparison site staff. The mean improvement of fidelity scores among i-THRIVE sites was 16.7, and 8.8 among comparison sites; the weighted model did not find a statistically significant difference. However, results show that strong working relationships in the local system significantly enhance the effectiveness of i-THRIVE. Sites with highly effective working relationships showed a notable improvement in ‘THRIVE-like’ features, with an average increase of 16.41 points (95% confidence interval: 1.69–31.13, P-value: 0.031) over comparison sites. Sites with ineffective working relationships did not benefit from i-THRIVE (−2.76, 95% confidence interval: − 18.25–12.73, P-value: 0.708).
Conclusions
The findings underscore the importance of working relationship effectiveness in the successful adoption and implementation of multi-agency health policies like i-THRIVE.
This study assessed whether a music therapy program improved mental health and school attendance among girls in the Democratic Republic of Congo (DRC) following economic and conflict-related insecurity. It included 483 girls aged 10–14 who participated in the Healing in Harmony (HiH) program, implemented by World Vision and Make Music Matter in Kasai-Central province. Participants completed surveys before and after the program, and up to two follow-up interviews assessing depression, anxiety, self-esteem, and school attendance. Before the program, 36.0% (95% CI 31.7%–40.3%) and 60.5% (95% CI 56.1%–64.8%) screened positive for depression and anxiety, respectively. After participation, the risk of screening positive declined by 75% for depression (RR = 0.27, 95% CI 0.22–0.32) and by about half for anxiety (RR = 0.46, 95% CI 0.41–0.53), with improvements sustained up to 17 months. Self-esteem scores increased by 3.93 points (95% CI 3.22–4.64, p<0.001). School absenteeism decreased from 10% (95% CI 7.2%–12.6%) to 5.4% (RR = 0.54, 95% CI 0.40–0.73). Participation in HiH was associated with sustained improvements in mental health and school attendance. These findings support integrating psychosocial care into humanitarian responses to improve both mental health and educational outcomes for crisis-affected children.
Hong Kong’s 3-year dynamic zero-COVID policy has caused prolonged exposure to stringent, pervasive anti-epidemic measures, which poses additional stressors on emotional well-being through pandemic fatigue, beyond the incumbent fear of the pandemic.
Aims
To investigate how major policy shifts in the zero-COVID strategy have corresponded with changing relationships between emotional well-being, pandemic fatigue from policy adherence, and pandemic fear, following the pandemic peak to a living-with-COVID policy.
Method
A three-wave repeated cross-sectional study (N = 2266) was conducted on the Chinese working-age population (18–64 years) during the peak outbreak (Wave 1), and subsequent policy shifts towards a living-with-COVID policy during the initial relaxation (Wave 2) and full relaxation (Wave 3) of anti-epidemic measures from March 2022 to March 2023. Non-parametric tests, consisting of robust analysis of covariance tests and quantile regression analysis, were performed.
Results
The severity of all measures was lowered after Wave 1; however, extreme pandemic fears reported in Wave 2 (n = 38, 7.7%) were associated with worse emotional well-being than the pandemic peak (Wave 1), which then subsided in Wave 3. Pandemic fatigue posed greater negative emotional well-being in Wave 1, whereas pandemic fear was the dominant predictor in Waves 2 and 3.
Conclusions
Pandemic fatigue and pandemic fear together robustly highlight the psychological cost of prolonged pandemic responses, expanding on a framework for monitoring and minimising the unintended mental health ramifications of anti-epidemic policies.
In the ‘classic’ sense, health professionals often view the health of individuals from a three-part biopsychosocial model of health. In this case, the ‘psych’ part relates directly to ‘mental health’. However, it is important to resist the temptation to separate this part from the bio and social aspects of the well-established model. Instead, it is best to view all parts of the established model as equally important and inter-related to each other. For instance, it is difficult to maintain good mental health and well-being if we lack either good social or ‘bio’ (physical) health. Traditionally, however, health professionals have tended to focus on the physical health component of the biopsychosocial model, especially those working in acute hospital/clinic environments. From a primary health care perspective, the ‘social’ (community development-focused) aspect is supposed to be the most dominant part of the model.
The cumulative effects of long-term exposure to pandemic-related stressors and the severity of social restrictions may have been important determinants of mental distress in the time of COVID-19.
Aim
This study aimed to investigate mental health among a cohort of Chinese university students over a 28-month period, focusing on the effects of lockdown type.
Methods
Depression, anxiety, stress and fear of COVID-19 infection were measured ten times among 188 Chinese students (females 77.7%, meanage = 19.8, s.d.age = 0.97), every 3 months: from prior to the emergence of COVID-19 in November 2019 (T1) to March 2022 (T10).
Results
Initially depression, anxiety and stress dipped from T1 to T2, followed by a sudden increase at T3 and a slow upward rise over the remainder of the study period (T3 to T10). When locked down at university, participants showed greater mental distress compared with both home lockdown (d = 0.35–0.48) and a no-lockdown comparison period (d = 0.28–0.40). Conversely, home lockdown was associated with less anxiety and stress (d = 0.19 and 0.21, respectively), but not with depression (d = 0.13) compared with a no-lockdown period.
Conclusions
This study highlights the cumulative effects of exposure to COVID-19 stressors over time. It also suggests that the way in which a lockdown is carried out can impact the well-being of those involved. Some forms of lockdown appear to pose a greater threat to mental health than others.