Societal concerns on the environmental impact of manufacturing activities in developing economies have intensified over the past decade. Open innovation (OI) has emerged as a promising approach to mitigate these adverse effects without compromising sustainable performance (SP). This primary aim of this study is to examine and evaluate the current state of research on OI and SP practices for further empirical studies in developing economies. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework, we systematically reviewed and analysed 108 articles from Scopus, Web of Science, Google Scholar, and ScienceDirect databases related to OI and SP practices. Our study highlights significant knowledge gaps in the relationship between OI and SP in manufacturing, noting a predominant focus on developed countries. This research contributes to the existing literature by identifying critical contextual and theoretical gaps, providing valuable insights and theoretical implications for future OI and SP research agendas in developing countries.