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Effects of Guanidinoacetic acid supplements on laying performance, egg quality, liver nitric oxide and energy metabolism in laying hens at the late stage of production

Published online by Cambridge University Press:  02 July 2020

Ayman S. Salah ,
Omar A. Ahmed-Farid  and
Mahmoud S. El-Tarabany Open the ORCID record for Mahmoud S. El-Tarabany [Opens in a new window]
Ayman S. Salah
Affiliation:
Department of Animal Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, New Valley University, New Valley, Egypt
Omar A. Ahmed-Farid
Affiliation:
Physiology Department, National Organization for Drug Control and Research (NODCAR), Cairo, Egypt
Mahmoud S. El-Tarabany*
Affiliation:
Department of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Egypt
*
Author for correspondence: Mahmoud S. El-Tarabany, E-mail: mahmoudtarabany2887@yahoo.com, mmohamedibrahim@zu.edu.eg
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Abstract

The objective was to elucidate the effects of dietary supplementation with guanidinoacetic acid (GAA) on performance, egg quality and the liver antioxidant activity of laying hens. A total of 128, 72-week-old ISA Brown laying hens were randomly divided into four equal groups (32 birds), and each subgroup had eight replicates (four birds/cage). The control group (GAA0) fed the basal diet with no supplements, while the other experimental groups fed the basal diets supplemented with 0.5 (GAA1), 1.0 (GAA2) and 1.5 (GAA3) g of GAA/kg diet. The experiment lasted for 6 weeks. The addition of GAA at a rate of 1.5 g kg−1 significantly increased the hen-day egg production and egg mass as compared to the control group (P = 0.016 and 0.003, respectively). Although the egg weight was not affected (P = 0.521) by the dietary supplements, the shell ratio, shell thickness, yolk index and Haugh units increased linearly with the increase in the dietary supplements of the GAA (P = 0.036, 0.001, 0.012 and 0.004, respectively). The liver MDA levels decreased linearly with the increment in the dietary levels of the GAA (P = 0.012). Birds in the GAA2 and GAA3 showed a significantly higher liver nitric oxide level (52.50 and 54.21 mg/g, respectively) when compared with GAA0 and GAA1 groups (P = 0.029). Compared to the GAA0 group, all GAA-supplemented groups showed significantly higher liver ATP levels (P = 0.047). In conclusion, the dietary GA supplements at doses of 1.0 or 1.5 g kg−1 may improve the laying performance, antioxidant activity and the status of cellular energy metabolism in laying hens.

Keywords

Guanidinoacetic acidlaying hensmetabolismperformance
Type
Animal Research Paper
Information
The Journal of Agricultural Science , Volume 158 , Issue 3 , April 2020 , pp. 241 - 246
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Copyright
Copyright © The Author(s), 2020. Published by Cambridge University Press

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