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Quality of life of children with sleep-disordered breathing treated with adenotonsillectomy

Published online by Cambridge University Press:  27 September 2010

S M Powell ,
M Tremlett  and
D A Bosman
S M Powell*
Affiliation:
Department of Otolaryngology, James Cook University Hospital, Middlesbrough, UK
M Tremlett
Affiliation:
Department of Anaesthesia, James Cook University Hospital, Middlesbrough, UK
D A Bosman
Affiliation:
Department of Otolaryngology, James Cook University Hospital, Middlesbrough, UK
*
Address for correspondence: Mr S M Powell, Department of Otolaryngology, James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW, UK Fax: (0)1642 282756 E-mail: steven_m_powell@hotmail.com
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Abstract

Objective:

To assess the quality of life of UK children with sleep-disordered breathing undergoing adenotonsillectomy, by using the Obstructive Sleep Apnoea 18 questionnaire and determining score changes and effect sizes.

Design:

Prospective, longitudinal study.

Setting:

The otolaryngology department of a university teaching hospital in Northern England.

Participants:

Twenty-eight children for whom adenotonsillectomy was planned as treatment for sleep-disordered breathing, and who had either a clinical history consistent with obstructive sleep apnoea or a polysomnographic diagnosis.

Main outcome measure:

The Obstructive Sleep Apnoea 18 questionnaire, a previously validated, disease-specific quality of life assessment tool; changes in questionnaire scores and effect sizes were assessed.

Methods:

The Obstructive Sleep Apnoea 18 questionnaire was administered to each child's parent pre-operatively, then again at the follow-up appointment. Questionnaire scores ranged from 1 to 7. Score changes were analysed using the paired t-test; effect sizes were calculated using 95 per cent confidence intervals.

Results:

Complete data were obtained for 22 children (mean age, 61 months). Ten had undergone pre-operative polysomnography. Twenty-one children underwent adenotonsillectomy (one underwent tonsillectomy). Median follow up was eight weeks (interquartile range, six to 11 weeks). Following surgery, the overall mean score improvement was 2.6 (p < 0.0001) and the mean effect size 2.4 (95 per cent confidence interval 1.9 to 2.8). There were significant improvements in each of the individual questionnaire domains, i.e. sleep disturbance (mean score change 3.9, p < 0.0001), physical suffering (2.2, p < 0.0001), emotional distress (2.0, p = 0.0001), daytime problems (1.8, p = 0.0001) and caregiver concerns (2.6, p < 0.0001).

Conclusion:

In these children with sleep-disordered breathing treated by adenotonsillectomy, Obstructive Sleep Apnoea 18 questionnaire results indicated significantly improved mean score changes and effect sizes across all questionnaire domains, comparing pre- and post-operative data.

Keywords

TonsillectomyAdenoidectomySleep-Disordered Breathing
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 2 , February 2011 , pp. 193 - 198
Copyright
Copyright © JLO (1984) Limited 2010

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Footnotes

Presented in part at the British Association of Paediatric Otolaryngology Meeting, 12 September 2008, Epsom, UK.

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