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library synthesis

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4 results in Keywords: library synthesis

An Integrated Direct-to-Biology Platform for the Nanoscale Synthesis and Biological Evaluation of PROTACs

Rebecca Stevens, Enrique Bendito-Moll, David Battersby, Afjal Miah, Natalie Wellaway, Robert Law, Peter Stacey, Diana Klimaszewska, Justyna Macina, Glenn Burley, John Harling

Version 2 posted 01 September 2023

1,728

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1

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by ChemRxiv

Rapid PROTAC discovery platform: nanomole scale array synthesis and direct screening of reaction mixtures to facilitate the expedited discovery and follow-up of PROTAC hits.

Mateusz Plesniak, Emilia K. Taylor, Frederik Eisele, Christopher M. B. K. Kourra, Iacovos Michaelides, Alice Oram, Johan Wernevik, Zulma Santisteban-Valencia, Hannah Rowbottom, Nadia Mann, Linda Fredlund, Valentyna Pivnytska, Anna Noven, Mohammad Pirmoradian, Thomas Lundback, R. Ian Storer, Mariell Pettersson, Gian Marco De Donatis, Marie Rehnstrom

Version 1 posted 18 July 2023

1,688

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by ChemRxiv

Antibiotic Discovery with Synthetic Fermentation: Library Assembly, Phenotypic Screening, and Mechanism of Action of Beta-Peptides Targeting Penicillin-Binding Proteins

Iain A. Stepek, Trung Cao, Anika Koetemann, Satomi Shimura, Bernd Wollscheid, Jeffrey Bode

Version 1 posted 27 March 2019

911

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by ChemRxiv

Unlocking the Potential of High-Throughput Experimentation for Electrochemistry with a Standardized Microscale Reactor

Jonas Rein, James R. Annand, Michael K. Wismer, Jiantao Fu, Juno C. Siu, Artis Klapars, Neil A. Strotman, Dipannita Kalyani, Dan Lehnherr, Song Lin

Version 2 posted 11 March 2021

1,418

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3

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by ChemRxiv