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Evolution, Cell Biology, and the Development of Multicellularity

Part of Developmental and Cell Biology Series

  • Date Published: August 2010
  • availability: Available
  • format: Paperback
  • isbn: 9780521152822


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About the Authors
  • Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.

    • A comprehensive book which covers all aspects of Dictyostelid research and biology
    • Covers both classical studies and modern findings
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    Reviews & endorsements

    Review of the hardback: '… a beautiful balance between the well understood and the relatively unexplored … it offers so much in such a tiny volume. I thoroughly recommend it.' P. R. Fisher, Soil Biology and Biochemistry

    Review of the hardback: '… a major achievement and will serve the field well for several years to come.' Jeffrey Williams, Trends in Genetics

    Review of the hardback: '… an excellent and up-to-date summary of how social amoebae do it, and is bristling with fascinating biological answers and questions.' John A. Lee, Geologist

    Review of the hardback: 'This book is an excellent and up-to-date summary of how social amoebae do it, and is bristling with fascinating biological answers and questions.' Biologist

    Review of the hardback: '… well organized and superbly presented … easy to read and very accessible to the newcomer to the field … the time is certainly right for a book to introduce this organism and its research to a wider audience. This is the ideal book.' Peter A. Thomason, Nature Cell Biology

    Review of the hardback: 'This will be the key reference work on this fascinating genus for decades, and a 'must' not only for developmental biologists but also the many mycologists who continue to dabble in and be fascinated by slime moulds.' Mycol. Research

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    Product details

    • Date Published: August 2010
    • format: Paperback
    • isbn: 9780521152822
    • length: 318 pages
    • dimensions: 229 x 152 x 18 mm
    • weight: 0.47kg
    • availability: Available
  • Table of Contents

    1. A brief introduction to Dictyostelium discoideum and its relatives
    2. A history of research on Dictyostelium discoideum
    3. The evolutionary biology of Dictyostelium
    4. The genome and genetics
    5. Membranes and organelles of Dictyostelium
    6. Cell motility and the cytoskeleton
    7. The transition from growth to development: from starvation to self sustaining cAMP signal relay
    8. Chemotaxis and aggregation
    9. Differentiation and adhesion in the aggregate
    10. Behavior of cells in the slug
    11. Culmination
    12. Formation and germination of spores
    13. Resources

  • Resources for


    Richard H. Kessin

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  • Author

    Richard H. Kessin, Columbia University, New York

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