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Essential Bioinformatics

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textbook
  • Date Published: March 2006
  • availability: Available
  • format: Paperback
  • isbn: 9780521600828

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  • Essential Bioinformatics is a concise yet comprehensive textbook of bioinformatics, which provides a broad introduction to the entire field. Written specifically for a life science audience, the basics of bioinformatics are explained, followed by discussions of the state-of-the-art computational tools available to solve biological research problems. All key areas of bioinformatics are covered including biological databases, sequence alignment, genes and promoter prediction, molecular phylogenetics, structural bioinformatics, genomics and proteomics. The book emphasizes how computational methods work and compares the strengths and weaknesses of different methods. This balanced yet easily accessible text will be invaluable to students who do not have sophisticated computational backgrounds. Technical details of computational algorithms are explained with a minimum use of mathematical formulae; graphical illustrations are used in their place to aid understanding. The effective synthesis of existing literature as well as in-depth and up-to-date coverage of all key topics in bioinformatics make this an ideal textbook for all bioinformatics courses taken by life science students and for researchers wishing to develop their knowledge of bioinformatics to facilitate their own research.

    • Concise yet comprehensive and written specifically for life scientists and those without a sophisticated computational background
    • Provides annotated guides to the most frequently used internet tools for each topic and discusses the advantages of different methods
    • Includes 6 step-by-step protocols for internet-based exercises to aid student's problem-solving skills using freely available bioinformatics tools
    • Glossary provides clear definitions and easy understanding of key bioinformatics concepts and tools
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    Reviews & endorsements

    'Essential Bioinformatics is a welcome addition to this area, by having a broad general approach that I think is particularly suitable for undergraduate teaching. The advantage of this being a new book is that there is not an overriding focus on structural bioinformatics that was seen in some earlier texts, which allows for a much broader coverage of newer areas like comparative and functional genomics.' http://www.sgm.ac.uk/pubs/micro_today/book_reviews/MTNOV06/MTN06_31.cfm

    'The book would be ideal for biologists who wish to gain a grasp of the different analysis techniques available to the microarray user.' http://www.sgm.ac.uk/pubs/micro_today/book_reviews/MTAUG04/MTA04_13.cfm

    'Awareness of bioinformatics is essential in a modern microbiological qualification and as this subject matures there are an increasing number of texts available. Essential Bioinformatics is a welcome addition to this area, by having a broad general approach that I think is particularly suitable for the undergraduate teaching.' Gavin Thomas, University of York

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    Product details

    • Date Published: March 2006
    • format: Paperback
    • isbn: 9780521600828
    • length: 352 pages
    • dimensions: 254 x 177 x 21 mm
    • weight: 0.82kg
    • contains: 9 tables
    • availability: Available
  • Table of Contents

    Preface
    Part I. Introduction and Biological Databases:
    1. Introduction
    2. Introduction to biological databases
    Part II. Sequence Alignment:
    3. Pairwise sequence alignment
    4. Database similarity search
    5. Multiple sequence alignment
    6. Profiles and hidden Markov models
    7. Protein motifs and patterns
    Part III. Gene and Promoter Prediction:
    8. Gene prediction
    9. Promoter and regulatory element prediction
    Part IV. Molecular Phylogenetics:
    10. Phylogenetics basics
    11. Phylogenetic tree construction methods and programs
    Part V. Protein Structure Basics:
    12. Protein structure basics
    13. Protein structure visualization, comparison and classification
    14. Protein secondary structure prediction
    15. Protein tertiary structure prediction
    16. RNA structure prediction
    Part VI. Genomics and Proteomics:
    17. Genome mapping, assembly and comparison
    18. Functional genomics
    19. Proteomics
    Practical exercises
    Glossary.

  • Resources for

    Essential Bioinformatics

    Jin Xiong

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  • Instructors have used or reviewed this title for the following courses

    • Advance topics in Biology
    • Bioinformatics
    • Introduction to Bioinformatics
    • functional genomics
  • Author

    Jin Xiong, Texas A & M University
    Jin Xiong is Assistant Professor of Biology at Texas A & M University, where he has taught bioinformatics to graduate and undergraduate students for several years.

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