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Cerebral Microbleeds
Pathophysiology to Clinical Practice

£82.99

Vladimir Hachinski, Varinder Singh Alg, David J. Werring, Maarten J. Versluis, Andrew G. Webb, Mark A. van Buchem, E. Mark Haacke, Alexander S. Boikov, Samuel Barnes, Jaladhar Neelavalli, M. Ayaz Khan, Simone M. Gregoire, Neshika Samarasekera, Gillian Potter, Rustam Al-Shahi Salman, Sebastian Brandner, Lenore J. Launer, Eric E. Smith, Cheryl R. McCreary, Bo Norrving, Seung-Hoon Lee, Jae-Kyu Roh, Roland N. Auer, Anand Viswanathan, Steven M. Greenberg, Charlotte Cordonnier, Wiesje M. van der Flier, Rainer Scheid, Hugues Chabriat, Martin Dichgans, Hans Rolf Jäger, Mike O'Sullivan, Yannie O. Y. Soo, Lawrence K. S. Wong, Chelsea S. Kidwell
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  • Date Published: May 2011
  • availability: In stock
  • format: Hardback
  • isbn: 9780521198455

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  • Stroke is a leading cause of death and disability throughout the world. About one in three symptomatic strokes are due to disease of small perforating arteries; however, most effective interventions are targeted at disease of large arteries. The underlying mechanisms and treatment of small vessel disease remain poorly understood. Microbleeds have emerged as a critical imaging marker of small vessel disease, being found in all types of stroke. With increasing evidence that microbleeds are caused by hypertensive arteriopathy and cerebral amyloid angiopathy, they are likely to play a strong future role in increasing our understanding of the causes of small vessel disease and the potential link between cerebrovascular disease and neurodegeneration. Cerebral Microbleeds summarizes our current knowledge, bringing together expert research from global authorities in the field. This authoritative and systematic text will be of interest to all clinical researchers and physicians in the fields of stroke and cognitive impairment.

    • Draws together the available research on microbleeds into one accessible volume
    • Easy access to all relevant research with authoritative information and discussion
    • Systematically covers all aspects from pathology to clinical practice
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    Reviews & endorsements

    'Cerebral Microbleeds: Pathophysiology to Clinical Practice is a 198-page textbook that covers the entire current state of knowledge on microbleeds, ranging from the historical perspective to current imaging methods and histopathology … David Werring has succeeded in assembling virtually all authorities on cerebral microbleeds to share their knowledge and views on this emerging topic. This has yielded a comprehensive overview that is of interest both to the uninitiated student wanting to know what all the fuss is about and to the more experienced neuroscientist working in the field of cerebral small vessel disease.' The Lancet

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    Product details

    • Date Published: May 2011
    • format: Hardback
    • isbn: 9780521198455
    • length: 198 pages
    • dimensions: 253 x 195 x 15 mm
    • weight: 0.59kg
    • contains: 85 b/w illus.
    • availability: In stock
  • Table of Contents

    Preface
    Foreword Vladimir Hachinski
    A short note on terminology
    Part I. Historical Aspects, Detection and Interpretation:
    1. Historical overview: microaneurysms, cerebral microbleeds and intracerebral hemorrhage Varinder Singh Alg and David J. Werring
    2. Detection of microbleeds – physical principles, technical aspects and new developments Maarten J. Versluis, Andrew G. Webb and Mark A. van Buchem
    3. Susceptibility-weighted imaging E. Mark Haacke, Alexander S. Boikov, Samuel Barnes, Jaladhar Neelavalli and M. Ayaz Khan
    4. Defining and mapping cerebral microbleeds Simone M. Gregoire and David J. Werring
    5. Microbleed mimics Neshika Samarasekera, Gillian Potter and Rustam Al-Shahi Salman
    Part II. Mechanisms Underlying Microbleeds:
    6. Histopathology of cerebral microbleeds Sebastian Brandner
    7. Risk factors for cerebral microbleeds Lenore J. Launer
    8. Relationship of cerebral microbleeds to other imaging findings Eric E. Smith, David J. Werring and Cheryl R. McCreary
    Part III. Microbleeds in Relation to Specific Populations, Diseases and Neurological Symptoms:
    9. Microbleeds in healthy populations Bo Norrving
    10. Microbleeds in relation to cerebrovascular disease Seung-Hoon Lee and Jae-Kyu Roh
    11. Microbleeds in relation to hypertensive arteriopathy Eric E. Smith and Roland N. Auer
    12. Microbleeds in relation to cerebral amyloid angiopathy M. Ayaz Khan, Anand Viswanathan and Steven M. Greenberg
    13. Cerebral microbleeds and Alzheimer's disease Charlotte Cordonnier and Wiesje M. van der Flier
    14. Cerebral microbleeds in relation to brain trauma Rainer Scheid
    15. Cerebral microbleeds in CADASIL Anand Viswanathan, Hugues Chabriat and Martin Dichgans
    16. Miscellaneous conditions associated with cerebral microbleeds David J. Werring and Hans Rolf Jäger
    17. Cerebral microbleeds and cognitive impairment David J. Werring and Mike O'Sullivan
    18. Other clinical manifestations of cerebral microbleeds Simone M. Gregoire and David J. Werring
    19. Cerebral microbleeds and antithrombotic treatment Yannie O. Y. Soo and Lawrence K. S. Wong
    20. Cerebral microbleeds and thrombolysis Chelsea S. Kidwell
    Index.

  • Editor

    David J. Werring, Institute of Neurology, London
    David J. Werring is Clinical Senior Lecturer and Consultant Neurologist at the UCL Institute for Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

    Contributors

    Vladimir Hachinski, Varinder Singh Alg, David J. Werring, Maarten J. Versluis, Andrew G. Webb, Mark A. van Buchem, E. Mark Haacke, Alexander S. Boikov, Samuel Barnes, Jaladhar Neelavalli, M. Ayaz Khan, Simone M. Gregoire, Neshika Samarasekera, Gillian Potter, Rustam Al-Shahi Salman, Sebastian Brandner, Lenore J. Launer, Eric E. Smith, Cheryl R. McCreary, Bo Norrving, Seung-Hoon Lee, Jae-Kyu Roh, Roland N. Auer, Anand Viswanathan, Steven M. Greenberg, Charlotte Cordonnier, Wiesje M. van der Flier, Rainer Scheid, Hugues Chabriat, Martin Dichgans, Hans Rolf Jäger, Mike O'Sullivan, Yannie O. Y. Soo, Lawrence K. S. Wong, Chelsea S. Kidwell

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