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This comprehensive and cogent survey examines the subject of embryonic determination, the set of processes fundamental to animal development by which cells in the early embryo acquire different developmental capabilities. Examining both the classical literature and the newer, molecular findings, the author summarizes the current state of our understanding of determination and poses key questions for the future. He begins with a consideration of how much spatial pattern is already laid down when the egg forms inside the mother, and ends just before the formation of visible organs. Within these limits he also considers evidence obtained by a variety of techniques, both experimental and biochemical, derived from the embryos of a variety of animal groups. This is a suitable text for upper level undergraduates, graduate students and researchers in developmental biology.
Reviews & endorsements
"...an important addition to the developmental biologist's bookshelves." ScienceSee more reviews
"...an invaluable source of reference. In particular, the author has helped rescue from oblivion many classical experimental results that have progressively disappeared from textbooks simply because they either could not be approached by contemporary molecular techniques, or simply because they could not be explained by existing theoretical models." Pere Alberch, Quarterly Review of Biology
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- Date Published: July 2005
- format: Paperback
- isbn: 9780521017268
- length: 452 pages
- dimensions: 230 x 160 x 30 mm
- weight: 0.687kg
- availability: Available
Table of Contents
2. From oocyte to zygote
3. Does cleavage cut up a preformed spatial pattern?
4. The limits of mosaicism in non-spiralian cleavage
5. Cellular interations in the morula and blastula: the case of sea urchin embryos
6. Interactions at morula and blastula in other embryos
7. Interactions between moving cells: the case of amphibian gastrulae
8. Spatial determination in the gastrulae of other groups
9. Determination in embryos showing partial cleavage
10. Patterns and mechanisms in early spatial determination
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