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Blood Disorders in the Elderly

$184.00 (G)

Lodovico Balducci, William B. Ershler, Kushang V. Patel, Jack M. Guralnik, Oscar A. Cepeda, Julie K. Gammack, John E. Morley, Claudia Beghe, Gary Van Zant, David N. Haylock, Susan K. Nilsson, Rita Effros, France Laurencet, Gilbert Zulian, Cheryl Hardy, Yuping Deng, Stefan Gravenstein, Arati V. Rao, Harvey J. Cohen, Andrew S. Aartz, E. Nemeth, Tomas Ganz, Sally P. Stabler, Luigi Ferrucci, Dan L. Longo, Bindu Kanapuru, Magda Elkabani, Jeffrey Lancet, Salvatore Bruno, Femina Mazzella, Oscar Ballester, Todd J. Alekshun, Melissa Alsina, Nicole Jacobi, Bruce A. Peterson, Youssef Gamal, Samuel Kerr, Thomas P. Loughran, Alexander S. D. Spiers, Jerry L. Spivak, F. Baudo, F. de Cataldo, Jozef Vermylen, Marc F. Hoylaerts, Laura Terranova, Giancarla Gerli, Marco Cattaneo, Daniela Mari, Chiara Cerletti, H. J. Schunemann, Giovanni de Gaetano
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  • Date Published: January 2008
  • availability: In stock
  • format: Hardback
  • isbn: 9780521875738

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About the Authors
  • The developed world has an increasingly aging population, with approximately 10% of the population aged over 65 years. As the incidence and prevalence of blood disorders increases with age, these conditions are a heavy burden on healthcare systems. Blood Disorders in the Elderly will provide hematologists, geriatricians and all clinicians involved in the care of patients with blood disorders with clear clinical advice on the diagnosis and management of these conditions. The introductory section reviews epidemiology of aging and anemia and provides a comprehensive approach to the management of cancer in the aging patient. This is followed by a full discussion of hemopoiesis and changes it undergoes in aging. The remaining sections cover the diagnosis and management of all major disorders: anemia, malignancy, coagulation and platelet disorders and hemophilia. A detailed chapter on antithrombotic therapies is also included.

    • Comprehensive coverage of all blood disorders from international experts in hematology and geriatric medicine
    • Introduction sections on epidemiology and changes in hemopoiesis with aging
    • Contains a 16 page color plate section to aid diagnosis of disorders
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    Reviews & endorsements

    'This is a brilliant contribution to the field. The excellent organisation of the book is matched by superb editing that provides an even tone of voice often lacking in multi-authored books. … This book will be the lodestone that directs future research in the haematology of old age.' David O. Staats, University of Oklahoma Health Sciences Center

    'Haematologic disorders, covering from mild to severe diseases are part of everyday practice in geriatric wards. For this reason this book could be welcome on the shelves of geriatricians dealing with internal medicine. … The subject of this book, if covered in detail, could fill an encyclopaedia. The authors managed to treat the…topics in a comprehensive manner, limiting thereby the volume of this treatise. The texts are written in an easily understandable style… The chapter headings…show clearly that the chosen topic is well covered, For these reasons this book is highly recommended for geriatric clinical practitioners.' Gerontology 2008

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    Product details

    • Date Published: January 2008
    • format: Hardback
    • isbn: 9780521875738
    • length: 496 pages
    • dimensions: 253 x 195 x 28 mm
    • weight: 1.248kg
    • contains: 24 b/w illus. 1 colour illus. 97 tables
    • availability: In stock
  • Table of Contents

    Introduction
    Part I. Epidemiology:
    1. Epidemiology of aging Lodovico Balducci and William B. Ershler
    2. Epidemiology of anemia: older adults Kushang V. Patel and Jack M. Guralnik
    3. Cancer in the older person: a comprehensive approach Oscar A. Cepeda, Julie K. Gammack and John E. Morley
    4. From fitness to frailty: toward a nosologic classification of the older aged person Lodovico Balducci and Claudia Beghe
    Part II. Hemopoiesis:
    5. Stem cell exhaustion and aging Gary Van Zant
    6. Hemopoietic micro-environment and age David N. Haylock and Susan K. Nilsson
    7. Replicative senescence, aging, and cancer Rita Effros
    8. Qualitative changes of hemopoiesis France Laurencet and Gilbert Zulian
    9. Aging and hemopoietic stress Lodovico Balducci and Cheryl Hardy
    10. Immunoglobulin response and aging Yuping Deng and Stefan Gravenstein
    11. Biological and clinical significance of monoclonal gammopathy Arati V. Rao and Harvey J. Cohen
    Part III. Anemia of Aging:
    12. Erythropoietin and aging Andrew S. Aartz
    13. Iron and aging E. Nemeth and Tomas Ganz
    14. Prevalence and mechanism of B12 deficiency Sally P. Stabler
    15. The consequences of anemia Luigi Ferrucci and Dan L. Longo
    16. The pathogenesis of late-life anemia Bindu Kanapuru and William B. Ershler
    17. Treatment of late-life anemia William B. Ershler
    Part IV. Hematological Malignancies and Aging:
    18. Cancer chemotherapy in the older person Lodovico Balducci
    19. Acute myeloid leukemia in the elderly Magda Elkabani and Jeffrey Lancet
    20. Acute lymphoblastic leukemia in elderly patients: diagnosis and therapy Salvatore Bruno, Femina Mazzella and Oscar Ballester
    21. Multiple myeloma Todd J. Alekshun and Melissa Alsina
    22. Non-Hodgkin lymphoma Nicole Jacobi and Bruce A. Peterson
    23. Unusual lymphomas in the elderly Youssef Gamal, Samuel Kerr and Thomas P. Loughran
    24. Chronic lymphocytic leukemia in the elderly Alexander S. D. Spiers
    25. Polycythemia vera and idiopathic myelofibrosis in the elderly Jerry L. Spivak
    Part V. Disorders of Hemostasis in the Elderly:
    26. Acquired hemophilia in the elderly F. Baudo and F. de Cataldo
    27. Blood coagulation and aging Jozef Vermylen and Marc F. Hoylaerts
    28. Platelet disorders in the elderly Laura Terranova, Giancarla Gerli and Marco Cattaneo
    29. Gene-environment interactions and vascular risk in the elderly Daniela Mari
    30. Antithrombotic therapy: guidelines for the elderly Chiara Cerletti, H. J. Schunemann and Giovanni de Gaetano.

  • Editors

    Lodovico Balducci, H. Lee Moffitt Cancer Center & Research Institute, Florida
    Lodovico Balducci is the Division Chief of the Senior Adult Oncology Program at the H. Lee Moffitt Cancer Center and Research Institute, Tampa, and Professor of Oncology and Medicine.

    William Ershler, Institute for Advanced Studies in Aging and Geriatric Medicine, Washington DC
    William Ershler is Director of the Institute for Advanced Studies in Aging and Geriatric Medicine, Washington DC.

    Giovanni de Gaetano, Catholic University, Campobasso
    Giovanni de Gaetano is Director of the Research Laboratories at the Centre for High Technology Research and Education in Biomedical Sciences, Catholic University, Campobasso, Italy.

    Contributors

    Lodovico Balducci, William B. Ershler, Kushang V. Patel, Jack M. Guralnik, Oscar A. Cepeda, Julie K. Gammack, John E. Morley, Claudia Beghe, Gary Van Zant, David N. Haylock, Susan K. Nilsson, Rita Effros, France Laurencet, Gilbert Zulian, Cheryl Hardy, Yuping Deng, Stefan Gravenstein, Arati V. Rao, Harvey J. Cohen, Andrew S. Aartz, E. Nemeth, Tomas Ganz, Sally P. Stabler, Luigi Ferrucci, Dan L. Longo, Bindu Kanapuru, Magda Elkabani, Jeffrey Lancet, Salvatore Bruno, Femina Mazzella, Oscar Ballester, Todd J. Alekshun, Melissa Alsina, Nicole Jacobi, Bruce A. Peterson, Youssef Gamal, Samuel Kerr, Thomas P. Loughran, Alexander S. D. Spiers, Jerry L. Spivak, F. Baudo, F. de Cataldo, Jozef Vermylen, Marc F. Hoylaerts, Laura Terranova, Giancarla Gerli, Marco Cattaneo, Daniela Mari, Chiara Cerletti, H. J. Schunemann, Giovanni de Gaetano

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