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Chronic Graft Versus Host Disease
Interdisciplinary Management

$281.00 (G)

Carrie Kitko, James L. M. Ferrara, Kirk Schultz, Yu-Wayne Chu, Ronald Gress, Warren D. Shlomchik, Sally Arai, Mukta Arora, Douglas Rizzo, Mary Evelyn D. Flowers, Georgia Vogelsang, Görgün Akpek, Stephanie J. Lee, Ernst Holler, Anne Dickinson, Madan Jagasia, Howard M. Shulman, Alexandra H. Filipovich, Steven Pavletic, T. Hughes, Timothy McGuire, Andrea Bacigalupo, Nelson J. Chao, Paul J. Martin, Andrew L. Gilman, Hildegard T. Greinix, Joseph H. Antin, David Jacobsohn, Sandra A. Mitchell, Paul A. Carpenter, Dan R. Couriel, Edward W. Cowen, Sharon R. Hynes, Nathaniel S. Treister, Mark M. Schubert, Jane M. Fall-Dickson, Stella K. Kim, Janine A. Smith, James P. Dunn Jr., Maria L. Turner, Pamela Stratton, Miwa Sakai, George B. McDonald, Javier Bolaños-Meade, Jason W. Chien, Corey Cutler, Harry Openshaw, Li Li, Leighton Chan, Lynn H. Gerber, Juan Gea-Banacloche, Michael Boeckh, Paul A. Carpenter, Jean E. Sanders, Kristin Baird, Andrew L. Gilman, Loretta Williams, Karen L. Syrjala, Gérard Socié, H. J. Deeg, Sandra A. Mitchell, Bryce B. Reeve, Paul J. Martin, Donna Przepiorka, Stephanie J. Lee, Mohamad Mohty, Juliet N. Barker, Claudio Anasetti, Kristin Baird, Alan S. Wayne, David A. Jacobsohn, Viki Anders, Carina Moravec, Sandra A. Mitchell, Kathleen M. Castro, Susan Stuart, Myra J. Jacobs, Paula Kim, Stephanie J. Lee
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  • Date Published: April 2009
  • availability: In stock
  • format: Hardback
  • isbn: 9780521884235

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About the Authors
  • Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi-system disorder. Practitioners need to be able to recognize and effectively manage chronic GVHD as a late effect of more than half of allogenic transplantations. The text is oriented for the clinician, with chapters covering staging, organ site and system-specific manifestations, treatment options, and supportive care. Drs. Georgia B. Vogelsang and Steven Z. Pavletic have been pioneers in the recognition of the multi-organ complexity of this disease and have gathered the input of a variety of subspecialist physicians for this book. This book fills the gap in practical literature on chronic GVHD, providing a comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant.

    • Comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant
    • Oriented for clinicians, covers staging, organ site and system specific manifestations, treatment options, and supportive care
    • Interdisciplinary, with contributions from all medical subspecialties
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    Reviews & endorsements

    'The editors, Drs Georgia B. Voselsang and Steven Z. Pavletic, pioneers in the recognition of the multi-organ complexity of this disease, have included in the writing of this book a refreshing variety of subspecialists… the very first textbook dedicated to the cGVHD. It is easy to predict that it will have [a] permanent place in medical history with [a] strong impact [on] future understanding of the disease. … excellent book.' Croatian Medical Journal

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    Product details

    • Date Published: April 2009
    • format: Hardback
    • isbn: 9780521884235
    • length: 436 pages
    • dimensions: 285 x 220 x 23 mm
    • weight: 1.53kg
    • contains: 50 b/w illus. 113 colour illus. 108 tables
    • availability: In stock
  • Table of Contents

    Part I. General Principles:
    1. History Alois Gratwohl
    2. Pathophysiology of acute GVHD Carrie Kitko and James L. M. Ferrara
    3. Pathophysiology of chronic GVHD Kirk Schultz
    4. Animal models of chronic GVHD Yu-Wayne Chu, Ronald Gress, and Warren D. Shlomchik
    5. Incidence and trends Sally Arai, Mukta Arora, and Douglas Rizzo
    6. Clinical manifestations and natural history Mary Evelyn D. Flowers and Georgia Vogelsang
    7. Risk factors and predictive models Görgün Akpek and Stephanie J. Lee
    8. Biomarkers in prediction and monitoring Ernst Holler and Anne Dickinson
    Part II. Clinical Management:
    9. Diagnosis and staging Madan Jagasia, Howard M. Shulman, Alexandra H. Filipovich, and Steven Pavletic
    10. Chronic GVHD pharmacology and commonly used drugs T. Hughes and Timothy McGuire
    11. Prevention of chronic GVHD Andrea Bacigalupo and Nelson J. Chao
    12. Front line treatment of chronic GVHD Paul J. Martin and Andrew L. Gilman
    13. Salvage treatment of chronic GVHD Hildegard T. Greinix and Joseph H. Antin
    14. Response measurement David Jacobsohn, Sandra A. Mitchell, and Steven Z. Pavletic
    15. General principles in ancillary and supportive care Paul A. Carpenter and Dan R. Couriel
    Part III. Organ Site or System Specific Manifestations:
    16. Skin Edward W. Cowen and Sharon R. Hynes
    17. Mouth Nathaniel S. Treister, Mark M. Schubert, and Jane M. Fall-Dickson
    18. Eyes Stella K. Kim, Janine A. Smith, and James P. Dunn Jr.
    19. Genitalia Maria L. Turner and Pamela Stratton
    20. Gastrointestinal (including nutritional support) Miwa Sakai and George B. McDonald
    21. Pulmonary Javier Bolaños-Meade and Jason W. Chien
    22. Hematologic Corey Cutler
    23. Neurologic Harry Openshaw
    24. Musculoskeletal Li Li, Leighton Chan, and Lynn H. Gerber
    25. Infections Juan Gea-Banacloche and Michael Boeckh
    26. Metabolic and endocrine effects Paul A. Carpenter and Jean E. Sanders
    27. Other manifestations Kristin Baird and Andrew L. Gilman
    28. Psycho-social issues Loretta Williams and Karen L. Syrjala
    29. Secondary and late effects Gérard Socié and H. J. Deeg
    30. Quality of life assessments Sandra A. Mitchell and Bryce B. Reeve
    Part IV. Special Considerations in Chronic GVHD:
    31. Clinical trials design Paul J. Martin, Donna Przepiorka, and Stephanie J. Lee
    32. Unique clinical situations Mohamad Mohty, Juliet N. Barker, and Claudio Anasetti
    33. Pediatric chronic GVHD Kristin Baird, Alan S. Wayne, and David A. Jacobsohn
    34. Coordination and continuity of interdisciplinary practice Viki Anders, Carina Moravec, and Sandra A. Mitchell
    35. Patient and family education, advocacy, and support groups Kathleen M. Castro, Susan Stuart, Myra J. Jacobs, and Paula Kim
    36. Future directions Stephanie J. Lee.

  • Editors

    Georgia B. Vogelsang, The Johns Hopkins University School of Medicine
    Georgia B. Vogelsang, MD, is Professor of Oncology at the Johns Hopkins University School of Medicine, Baltimore, Maryland.

    Steven Z. Pavletic, National Cancer Institute, Bethesda, Maryland
    Steven Z. Pavletic, MD, is the head of the Graft versus Host and Autoimmunity Unit in the Experimental Transplantation and Immunology Branch of the National Cancer Institute, Bethesda, Maryland.

    Contributors

    Carrie Kitko, James L. M. Ferrara, Kirk Schultz, Yu-Wayne Chu, Ronald Gress, Warren D. Shlomchik, Sally Arai, Mukta Arora, Douglas Rizzo, Mary Evelyn D. Flowers, Georgia Vogelsang, Görgün Akpek, Stephanie J. Lee, Ernst Holler, Anne Dickinson, Madan Jagasia, Howard M. Shulman, Alexandra H. Filipovich, Steven Pavletic, T. Hughes, Timothy McGuire, Andrea Bacigalupo, Nelson J. Chao, Paul J. Martin, Andrew L. Gilman, Hildegard T. Greinix, Joseph H. Antin, David Jacobsohn, Sandra A. Mitchell, Paul A. Carpenter, Dan R. Couriel, Edward W. Cowen, Sharon R. Hynes, Nathaniel S. Treister, Mark M. Schubert, Jane M. Fall-Dickson, Stella K. Kim, Janine A. Smith, James P. Dunn Jr., Maria L. Turner, Pamela Stratton, Miwa Sakai, George B. McDonald, Javier Bolaños-Meade, Jason W. Chien, Corey Cutler, Harry Openshaw, Li Li, Leighton Chan, Lynn H. Gerber, Juan Gea-Banacloche, Michael Boeckh, Paul A. Carpenter, Jean E. Sanders, Kristin Baird, Andrew L. Gilman, Loretta Williams, Karen L. Syrjala, Gérard Socié, H. J. Deeg, Sandra A. Mitchell, Bryce B. Reeve, Paul J. Martin, Donna Przepiorka, Stephanie J. Lee, Mohamad Mohty, Juliet N. Barker, Claudio Anasetti, Kristin Baird, Alan S. Wayne, David A. Jacobsohn, Viki Anders, Carina Moravec, Sandra A. Mitchell, Kathleen M. Castro, Susan Stuart, Myra J. Jacobs, Paula Kim, Stephanie J. Lee

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