Histiocytic Disorders of Children and Adults
Basic Science, Clinical Features and Therapy
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- Sheila Weitzman, University of Toronto
- R. Maarten Egeler, Rijksuniversiteit Leiden, The Netherlands
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This comprehensive reference on histiocytic disorders considers the genetics, pathophysiology, and clinical management of this wide range of diseases. It covers all aspects of hystiocytic disorders--from Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis, to the uncommon cutaneous and extracutaneous histiocytic disorders. Current views on the function of normal histiocytes in the immune system, the pathogenesis, underlying genetic defects, clinical presentation, treatment, controversies in therapy, salvage therapies and the late consequences are also presented.Read more
- A valuable resource for all physicians treating adults or children with a histiocytic disorder
- Written by leading experts in the field
- Provides a practical approach to diagnosis, treatment and management
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"This is the only current comprehensive text on histiocytic disorders...an essential addition to the libraries of those who are interested in these fascinating diseases."--Doody's Review Service
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- Date Published: September 2005
- format: Adobe eBook Reader
- isbn: 9780511113949
- availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
Table of Contents
Part I. Langerhans Cell Histiocytosis:
1. Introduction to the problem: overview, history, epidemiology and classification Sheila Weitzman and R. Maarten Egeler
2. The histopathology of Langerhans Cell Histiocytosis Ronald Jaffe
3. Histiocyte function and the normal immune system Tatjana Nikolic and Pieter Leenen
4. The immunologic basis of Langerhans Cell Histiocytosis Cristiana Costa, Nicola Annels and R Maarten Egeler
5. The genetics of Langerhans Cell Histiocytosis Maurizio Arico, S. Scappaticci and Cesare Danesino
6. Clinical aspects of Langerhans Cell Histiocytosis Jean Donadieu, Jon Pritchard and R. Maarten Egeler
7. Dermatologic aspects of the Histiocytic disorders Bernice Krafchik, Elena Pope and Scott Walsh
8. Langerhans Cell Histiocytosis of bone Sheila Weitzman and R. Maarten Egeler
9. Special aspects of Langerhans Cell Histiocytosis in the adult Maurizio Ariço, Emanuela De Juli, Thierry Genereau and Alan Saven
10. Adult lung Histiocytosis Tazi Abdellatif, Jeroen Hiltermann and Roberto Vassallo
11. Central nervous system involvement in Langerhans Cell Histiocytosis Nicole Grois, Helmut Prosch, Daniela Prayer and Hans Lassmann
12. The treatment of Langerhans Cell Histiocytosis Helmut Gadner and Stephan Ladisch
13. Novel and salvage therapies in Langerhans Cell Histiocytosis Sheila Weitzman, Kenneth McClain and Robert Arceci
14. Late effects of Langerhans Cell Histiocytosis and malignancy and LCH Riccardo Haupt, Vasanta Nanduri and R. Maarten Egeler
15. Uncommon Histiocytic disorders Sheila Weitzman and James Whitlock
Part II. Histiocytic Disorders Involving the Monocyte/Macrophage Pathway:
16. The histopathology of haemophagocytic lymphohistiocytosis Ronald Jaffe
17. Genetics and pathogenesis of hemophagocytic lymphohistiocytosis Kim Ericson, Bengt Fadeel and Jan-Inge Henter
18. Clinical aspects and therapy of hemophagocytic lymphohistiocytosis Gritta Janka, Jan-Inge Henter and Shinsaku Imashuku
19. Macrophage activation syndrome Ronald Laxer, Athimalaipet Ramanan and Rayfel Schneider
20. Malignant diseases of the mononuclear phagocytic system David Webb and Penelope Brock
21. Psychosocial aspects of the Histiocytic disorders Steven Simms, Elizabeth Kuh and Giulio D'Angio.
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