Book contents
- Neuroscience for Neurosurgeons
- Neuroscience for Neurosurgeons
- Copyright page
- Contents
- Contributors
- Section 1 Basic and Computational Neuroscience
- Section 2 Clinical Neurosurgical Diseases
- Chapter 12 Glioma
- Chapter 13 Brain Metastases: Molecules to Medicine
- Chapter 14 Benign Adult Brain Tumors and Pediatric Brain Tumors
- Chapter 15 Biomechanics of the Spine
- Chapter 16 Degenerative Cervical Myelopathy
- Chapter 17 Spondylolisthesis
- Chapter 18 Radiculopathy
- Chapter 19 Spinal Tumors
- Chapter 20 Acute Spinal Cord Injury and Spinal Trauma
- Chapter 21 Traumatic Brain Injury
- Chapter 22 Vascular Neurosurgery
- Chapter 23 Pediatric Vascular Malformations
- Chapter 24 Craniofacial Neurosurgery
- Chapter 25 Hydrocephalus
- Chapter 26 Peripheral Nerve Injury Response Mechanisms
- Chapter 27 Clinical Peripheral Nerve Injury Models
- Chapter 28 The Neuroscience of Functional Neurosurgery
- Chapter 29 Neuroradiology: Focused Ultrasound in Neurosurgery
- Chapter 30 Magnetic Resonance Imaging in Neurosurgery
- Chapter 31 Brain Mapping
- Index
- References
Chapter 26 - Peripheral Nerve Injury Response Mechanisms
from Section 2 - Clinical Neurosurgical Diseases
Published online by Cambridge University Press: 04 January 2024
- Neuroscience for Neurosurgeons
- Neuroscience for Neurosurgeons
- Copyright page
- Contents
- Contributors
- Section 1 Basic and Computational Neuroscience
- Section 2 Clinical Neurosurgical Diseases
- Chapter 12 Glioma
- Chapter 13 Brain Metastases: Molecules to Medicine
- Chapter 14 Benign Adult Brain Tumors and Pediatric Brain Tumors
- Chapter 15 Biomechanics of the Spine
- Chapter 16 Degenerative Cervical Myelopathy
- Chapter 17 Spondylolisthesis
- Chapter 18 Radiculopathy
- Chapter 19 Spinal Tumors
- Chapter 20 Acute Spinal Cord Injury and Spinal Trauma
- Chapter 21 Traumatic Brain Injury
- Chapter 22 Vascular Neurosurgery
- Chapter 23 Pediatric Vascular Malformations
- Chapter 24 Craniofacial Neurosurgery
- Chapter 25 Hydrocephalus
- Chapter 26 Peripheral Nerve Injury Response Mechanisms
- Chapter 27 Clinical Peripheral Nerve Injury Models
- Chapter 28 The Neuroscience of Functional Neurosurgery
- Chapter 29 Neuroradiology: Focused Ultrasound in Neurosurgery
- Chapter 30 Magnetic Resonance Imaging in Neurosurgery
- Chapter 31 Brain Mapping
- Index
- References
Summary
The peripheral nervous system(PNS) comprises spinal and cranial nerves, which include motor, sensory, and autonomic nerves, as well as their roots, trunks, plexuses, ganglia, and accompanying supportive connective tissue distal to the brain and spinal cord. It is located peripheral to the central nervous system(CNS), and has very little in the way of protection from injury. In contrast to the CNS, it has a much higher innate capacity for repair and recovery after injury. Despite its physiological diversity, the PNS has a highly organized and choreographed injury response mechanism partially explaining its improved outcomes post-injury. In this chapter, we discuss the pathophysiology of peripheral nerve injury(PNI) and its ensuing reparative response. Before delving into PNIs and their classifications, it is important to review the basic anatomic organization of the PNS, its key cellular components, and supporting connective tissue.
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- Neuroscience for Neurosurgeons , pp. 348 - 354Publisher: Cambridge University PressPrint publication year: 2024