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Chapter 6 - Management of Septicaemia and Septic Shock Antepartum, Intrapartum and Postpartum

from Section 2 - Algorithms for Management of the Top Five ‘Direct Killers’

Published online by Cambridge University Press:  06 May 2021

By
Karin Leslie  and
Sarah Hammond
Edited by
Edwin Chandraharan  and
Sir Sabaratnam Arulkumaran
Edwin Chandraharan
Affiliation:
St George's University of London
Sir Sabaratnam Arulkumaran
Affiliation:
St George's University of London
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Summary

The incidence of sepsis death is 4.7 per 10 000 maternities.

For each maternal sepsis death, approximately 50 women have life-threatening morbidity from sepsis. The rapid progression to severe sepsis highlights the importance of following the international Surviving Sepsis Campaign guideline of early administration of high-dose intravenous antibiotics within 1 hour of admission to hospital for anyone with suspected sepsis.

Signs of severe sepsis in peripartum women, particularly with confirmed or suspected group A streptococcal infection, should be regarded as an obstetric emergency.

Sepsis remains an important cause of maternal morbidity and mortality.

Type
Chapter
Information
Obstetric and Intrapartum Emergencies
A Practical Guide to Management
 , pp. 43 - 46
Publisher: Cambridge University Press
Print publication year: 2021

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References

NICE. Guideline NG51. Sepsis: Recognition, Diagnosis and Early Management, updated April 2019.Google Scholar
MBRRACE-UK. Saving lives, improving mother’s care: Lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2014–16.Google Scholar
Acosta, CD, Kurinczuk, JJ, Lucas, DN, Tuffnell, DJ, Sellers, S, Knight, M, United Kingdom Obstetric Surveillance System. Severe maternal sepsis in the UK, 2011–2012: a national case-control study. PLoS Med. 2014;11(7):e1001672.Google Scholar

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