Hostname: page-component-848d4c4894-5nwft Total loading time: 0 Render date: 2024-06-01T23:09:25.060Z Has data issue: false hasContentIssue false

Neonatal imitation and an epigenetic account of mirror neuron development

Published online by Cambridge University Press:  29 April 2014

Elizabeth A. Simpson
Affiliation:
Dipartimento di Biologia Evolutiva e Funzionale, Università di Parma, 43100 Parma, Italy. a.tramacere@gmail.compierfrancesco.ferrari@unipr.ithttp://mirroringdevelopment.uchicago.edu/project_3/people.shtmlhttp://www.unipr.it/arpa/mirror/english/staff/ferrarip.htm Laboratory of Comparative Ethology, Animal Center, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Dickerson, MD 20842. simpsonea@mail.nih.gov
Nathan A. Fox
Affiliation:
Department of Human Development and Quantitative Methodology, University of Maryland, College Park, MD 20742-1131. fox@umd.eduhttp://education.umd.edu/EDHD/faculty/Fox/
Antonella Tramacere
Affiliation:
Dipartimento di Biologia Evolutiva e Funzionale, Università di Parma, 43100 Parma, Italy. a.tramacere@gmail.compierfrancesco.ferrari@unipr.ithttp://mirroringdevelopment.uchicago.edu/project_3/people.shtmlhttp://www.unipr.it/arpa/mirror/english/staff/ferrarip.htm
Pier F. Ferrari
Affiliation:
Dipartimento di Biologia Evolutiva e Funzionale, Università di Parma, 43100 Parma, Italy. a.tramacere@gmail.compierfrancesco.ferrari@unipr.ithttp://mirroringdevelopment.uchicago.edu/project_3/people.shtmlhttp://www.unipr.it/arpa/mirror/english/staff/ferrarip.htm

Abstract

Neonatal imitation should not exclusively be considered at the population-level; instead, we propose that inconsistent findings regarding its occurrence result from important individual differences in imitative responses. We also highlight what we consider to be a false dichotomy of genetic versus learning accounts of the development of mirror neurons, and instead suggest a more parsimonious epigenetic perspective.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Arnstein, D., Cui, F., Keysers, C., Maurits, N. M. & Gazzola, V. (2011) μ-suppression during action observation and execution correlates with BOLD in dorsal premotor, inferior parietal, and SI cortices. Journal of Neuroscience 31(40):14243–49. doi: 10.1523/JNEUROSCI.0963-11.2011.CrossRefGoogle ScholarPubMed
Blekhman, R., Oshlack, A., Chabot, A. E., Smyth, G. K. & Gilad, Y. (2008) Gene regulation in primates evolves under tissue-specific selection pressures. PLoS Genetics 4(11):e1000271. doi: 10.1371/journal.pgen.1000271.CrossRefGoogle ScholarPubMed
Bonini, L. & Ferrari, P. F. (2011) Evolution of mirror systems: A simple mechanism for complex cognitive functions. Annals of the New York Academy of Sciences 1225:166–75. doi: 10.1111/j.1749-6632.2011.06002.x.CrossRefGoogle ScholarPubMed
Casile, A., Caggiano, V. & Ferrari, P. F. (2011) The mirror neuron system: A fresh view. Neuroscientist 17(5):524–38. doi: 10.1177/1073858410392239.Google Scholar
Chawarska, K., Macari, S. & Shic, F. (2013) Decreased spontaneous attention to social scenes in 6-month-old infants later diagnosed with autism spectrum disorders. Biological Psychiatry 74(3):195203. doi: 10.1016/j.biopsych.2012.11.022.CrossRefGoogle ScholarPubMed
de Waal, F. B. M. & Ferrari, P. F. (2010) Towards a bottom-up perspective on animal and human cognition. Trends in Cognitive Sciences 14:201–07. doi: 10.1016/j.tics.2010.03.003.Google Scholar
Del Giudice, M., Manera, V. & Keysers, C. (2009) Programmed to learn? The ontogeny of mirror neurons. Developmental Science 12(2):350–63. doi: 10.1111/j.1467-7687.2008.00783.x.Google Scholar
Domjan, M. & Galef, B. G. Jr. (1983) Biological constraints on instrumental and classical conditioning: Retrospect and prospect. Animal Learning and Behavior 11:151–61. doi: 10.3758/BF03199643.Google Scholar
Ferrari, P. F., Paukner, A., Ruggiero, A., Darcey, L., Unbehagen, S. & Suomi, S. J. (2009c) Interindividual differences in neonatal imitation and the development of action chains in rhesus macaques. Child Development 80(4):1057–68. doi: 10.1111/j.1467-8624.2009.01316.x.Google Scholar
Ferrari, P. F., Vanderwert, R. E., Paukner, A., Bower, S., Suomi, S. J. & Fox, N. A. (2012) Distinct EEG amplitude suppression to facial gestures as evidence for a mirror mechanism in newborn monkeys. Journal of Cognitive Neuroscience 24(5):1165–72. doi: 10.1162/jocn_a_00198.Google Scholar
Ferrari, P. F., Visalberghi, E., Paukner, A., Fogassi, L., Ruggiero, A. & Suomi, S. J. (2006) Neonatal imitation in rhesus macaques. PLoS Biology 4(9):1501–508, e302. doi: 10.1371/journal.pbio.0040302.Google Scholar
Heimann, M. (1989) Neonatal imitation, gaze aversion, and mother–infant interaction. Infant Behavior and Development 12:495505. doi: 10.1016/0163-6383(89)90029-5.Google Scholar
Jensen, P. (2013) Transgenerational epigenetic effects on animal behaviour. Progress in Biophysics and Molecular Biology 113(3):447–54. doi: 10.1016/j.pbiomolbio.2013.01.001.Google Scholar
Nagy, E., Pilling, K., Orvos, H. & Molnar, P. (2013) Imitation of tongue protrusion in human neonates: Specificity of the response in a large sample. Developmental Psychology 49(9):1628–38. doi: 10.1037/a0031127.Google Scholar
Paukner, A., Ferrari, P. F. & Suomi, S. J. (2011) Delayed imitation of lipsmacking gestures by infant rhesus macaques (Macaca mulatta). PLoS One 6(12):e28848. doi: 10.1371/journal.pone.0028848.Google Scholar
Paukner, A., Ferrari, P. F. & Suomi, S. J. (2013a) A comparison of neonatal imitation abilities in human and macaque infants. In: Navigating the social world: What infants, children, and other species can teach us, ed. Banaji, M. R. & Gelman, S. A., pp. 133138. Oxford University Press.CrossRefGoogle Scholar
Paukner, A., Simpson, E. A., Ferrari, P., Mrozek, T. & Suomi, S. J. (under review) Neonatal imitation predicts how infants engage with faces.Google Scholar
Paukner, A., Simpson, E. A., Ferrari, P. & Suomi, S. J. (2013b) Visual attention to a communicative gesture in infant macaques: Selective attention to the eye region in neonatal imitators. Paper presented at the Society for Research in Child Development Conference, Seattle, Washington, April 20, 2013.Google Scholar
Provençal, N., Suderman, M. J., Guillemin, C., Massart, R., Ruggiero, A., Wang, D., Bennett, A.J., Pierre, P. J., Friedman, D. P., Cote, S. M., Hallett, M., Tremblay, R. E., Suomi, S. J. & Szyf, M. (2012) The signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cells. The Journal of Neuroscience 32(44):15626–42. doi: 10.1523/JNEUROSCI.CrossRefGoogle ScholarPubMed
Reeb-Sutherland, B. C., Levitt, P. & Fox, N. A. (2012) The predictive nature of individual differences in early associative learning and emerging social behavior. PLoS ONE 7(1):e30511. doi: 10.1371/journal.pone.0030511.Google Scholar
Roth, T. L. (2012) Epigenetics of neurobiology and behavior during development and adulthood. Developmental Psychobiology 54(6):590–97. doi: 10.1002/dev.20550.Google Scholar
Sanefuji, W. & Ohgami, H. (2013) “Being-imitated” strategy at home-based intervention for young children with autism. Infant Mental Health Journal 34(1):7279. doi: 10.1002/imhj.21375.Google Scholar
Simpson, E. A., Paukner, A., Sclafani, V., Suomi, S. J. & Ferrari, P. F. (2013) Lipsmacking imitation skill in newborn macaques is predictive of social partner discrimination. PLoS ONE 8(12):e82921. doi: 10.1371/journal.pone.0082921Google Scholar
Simpson, E. A., Paukner, A., Suomi, S. J. & Ferrari, P. F. (2014) Visual attention during neonatal imitation in newborn macaque monkeys. Developmental Psychobiology 56(4):864–70. doi: 10.1002/dev.21146 CrossRefGoogle ScholarPubMed
Suddendorf, T., Oostenbroek, J., Nielsen, M. & Slaughter, V. (2012) Is newborn imitation developmentally homologous to later social-cognitive skills? Developmental Psychobiology 55:5458. doi: 10.1002/dev.21005.Google Scholar
Tachibana, M., Kagitani-Shimono, K., Mohri, I., Yamamoto, T., Sanefuji, W., Nakamura, A., Oishi, M., Kimura, T., Onaka, T., Ozono, K. & Taniike, M. (2013) Long-term administration of intranasal oxytocin is a safe and promising therapy for early adolescent boys with autism spectrum disorders. Journal of Child and Adolescent Psychopharmacology 23(2):123–27. doi: 10.1089/cap.2012.0048.Google Scholar