No CrossRef data available.
Article contents
Should we compromise on n-of-1 data analyses?
Published online by Cambridge University Press: 19 March 2024
Summary
Despite their increasing popularity, n-of-1 designs employ data analyses that might not be as complete and powerful as they could be. Borrowing from existing advances in educational and psychological research, this article presents a few techniques and references for rigorous data analytic techniques in n-of-1 research.
- Type
- Research Methods
- Information
- Copyright
- Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of Royal College of Psychiatrists
References
Hedges, LV, Pustejovsky, JE, Shadish, WR (2012) A standardized mean difference effect size for single case designs. Research Synthesis Methods, 3: 224–39.CrossRefGoogle ScholarPubMed
Hedges, LV, Pustejovsky, JE, Shadish, WR (2013) A standardized mean difference effect size for multiple baseline designs across individuals. Research Synthesis Methods, 4: 324–41.CrossRefGoogle ScholarPubMed
Hedges, LV, Shadish, WR, Natesan Batley, P (2023) Power analysis for single-case designs: computations for (AB)k designs. Behavioral Research Methods, 55, 3494–503.CrossRefGoogle ScholarPubMed
Huitema, BE, McKean, JW (2000) Design specification issues in time-series intervention models. Educational and Psychological Measurement, 60: 38–58.CrossRefGoogle Scholar
Kronish, IM, Hampsey, M, Falzon, L, et al (2018) Personalized (N-of-1) trials for depression: a systematic review. Clinical Psychopharmacology, 38: 218–25.CrossRefGoogle ScholarPubMed
Lévesque, M, Savard, J, Simard, S, et al (2004) Efficacy of cognitive therapy for depression among women with metastatic cancer: a single-case experimental study. Journal of Behavioral Therapy and Experimental Psychiatry, 35: 287–305.CrossRefGoogle ScholarPubMed
Marwick, KFM, Stevenson, AJ, Davies, C, et al (2018) Application of n-of-1 treatment trials in schizophrenia: systematic review. British Journal of Psychiatry, 213: 398–403.CrossRefGoogle ScholarPubMed
Mordijck, E, Danckaerts, M, Onghena, P (2018) [N-of-1 trials in child and adolescent psychiatry: a closer look at stimulants]. Tijdschrift Voor Psychiatrie, 60: 315–25.Google Scholar
Natesan, P, Hedges, LV (2017) Bayesian unknown change-point models to investigate immediacy in single case designs. Psychological Methods, 22(4): 743.CrossRefGoogle ScholarPubMed
Natesan Batley, P, Hedges, LV (2021) Accurate model vs. accurate estimates: a study of Bayesian single-case experimental designs. Behavior Research Methods, 53: 1782–98.CrossRefGoogle ScholarPubMed
Natesan Batley, P, McClure, EB, Brewer, B, et al (2023a) Evidence and reporting standards in N-of-1 medical studies: a systematic review. Translational Psychiatry, 13(1): 263.CrossRefGoogle ScholarPubMed
Natesan Batley, P (2023b) Bayesian analysis of single case experimental design count data in trauma research: a tutorial. Psychological Trauma, 15: 829–37.CrossRefGoogle ScholarPubMed
Natesan Batley, P, Thamaran, M, Hedges, LV (2023c) ABkPowerCalculator: an app to compute power for balanced (AB)k single case experimental designs. Multivariate Behavioral Research. [Epub ahead of print] 17 Oct. Available from: https://doi.org/10.1080/00273171.2023.2261229.CrossRefGoogle ScholarPubMed
Porcino, AJ, Shamseer, L, Chan, AW, et al (2020) SPIRIT extension and elaboration for n-of-1 trials: SPENT 2019 checklist. BMJ, 368: m122.CrossRefGoogle ScholarPubMed
Zuidersma, M, Riese, H, Snippe, E, et al (2020) Single-subject research in psychiatry: facts and fictions. Frontiers in Psychiatry, 11: 539777.CrossRefGoogle Scholar
eLetters
No eLetters have been published for this article.