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Alcohol Use Disorder in Patients with Chronic Migraine: A Retrospective, Observational Study
Published online by Cambridge University Press: 25 January 2024
Abstract:
Objective:
The relationship between migraine and alcohol consumption is unclear. We assessed the association between chronic migraine and alcohol use disorder(AUD), relative to chronic disease controls, and in conjunction with common comorbidities.
Methods:
We conducted a retrospective, observational study. The primary outcome was the odds ratio for AUD in patients with chronic migraine or with chronic migraine and additional comorbidities relative to controls.
Results:
A total of 3701 patients with chronic migraine, 4450 patients with low back pain, and 1780 patients with type 2 diabetes mellitus met inclusion criteria. Patients with chronic migraine had a lower risk of AUD relative to both controls of low back pain (OR 0.37; 95% CI: 0.29–0.47, p < 0.001) and type 2 diabetes mellitus (OR 0.39; 95% CI: 0.29–0.52, p < 0.001). Depression was associated with the largest OR for AUD in chronic migraine (OR 8.62; 95% CI: 4.99–14.88, p < 0.001), followed by post-traumatic stress disorder (OR 6.63; 95% CI: 4.13–10.64, p < 0.001) and anxiety (OR 3.58; 95% CI: 2.23–5.75, p < 0.001).
Conclusion:
Patients with chronic migraine had a lower odds ratio of AUD relative to controls. But in patients with chronic migraine, those with comorbid depression, anxiety, or PTSD are at higher risk of AUD. When patients establish care, comorbid factors should be assessed and for those at higher risk, AUD should be screened for at every visit.
Résumé :
Troubles liés à la consommation d’alcool chez des patients souffrant de migraine chronique : une étude rétrospective et observationnelle.
La relation qui existe entre la migraine et la consommation d’alcool n’est pas claire. À cet égard, nous avons cherché à évaluer l’association entre la migraine chronique et les troubles liés à la consommation d’alcool (TCA) en comparaison avec des témoins atteints de maladies chroniques et en conjonction avec des comorbidités communes.
Nous avons mené une étude rétrospective et observationnelle dont le principal résultat évalué était le rapport de cotes (RC) pour les TCA chez des patients souffrant de migraine chronique ou de migraine chronique et de comorbidités supplémentaires en comparaison avec des témoins.
Au total, 3 701 patients souffrant de migraine chronique, 4 450 patients souffrant de lombalgie et 1 780 patients atteints de diabète de type 2 ont répondu à nos critères d’inclusion. À noter que les patients souffrant de migraine chronique ont présenté un risque plus faible de TCA par rapport aux témoins atteints de lombalgie (RC 0,37 ; IC 95 % : 0,29-0,47; p < 0,001) et de diabète de type 2 (RC 0,39 ; IC 95 % : 0,29-0,52 ; p < 0,001). Ajoutons aussi que la dépression a été associée à un RC plus important pour les TCA associés à la migraine chronique (RC 8,62 ; IC 95 % : 4,99-14,88 ; p < 0,001) ; elle a été suivie par le trouble de stress post-traumatique (TSPT) (RC 6,63 ; IC 95 % : 4,13-10,64 ; p < 0,001) et l’anxiété (RC 3,58 ; IC 95 % : 2,23-5,75 ; p < 0,001).
Les patients souffrant de migraine chronique ont présenté un RC des TCA inférieur à celui des témoins. Cela dit, les patients souffrant de migraine chronique ainsi que ceux qui présentent une comorbidité telle que la dépression, l’anxiété ou le TSPT ont donné à voir un risque plus élevé de souffrir de TCA. Ainsi donc, lorsque des patients commencent à recevoir des soins, ces facteurs de comorbidité devraient être évalués. De plus, pour ceux qui présentent un risque plus élevé, les TCA devraient faire l’objet d’un dépistage à chaque visite.
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- © The Author(s), 2024. Published by Cambridge University Press on behalf of Canadian Neurological Sciences Federation
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