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Discrimination of the Cognitive Profiles of MCI and Depression using the KBNA

Published online by Cambridge University Press:  23 September 2014

Michelle C. E. Monette  and
Larry Leach
Michelle C. E. Monette
Affiliation:
Department of Psychology, University of Windsor, Windsor
Larry Leach*
Affiliation:
Neuropsychology & Cognitive Health Program, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
*
Neuropsychology & Cognitive Health Program, Baycrest Centre for Geriatric Care, Toronto, Ontario, M6a 2E1, Canada. Email: lleach@baycrest.org
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Abstract:

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Objective:

The current study sought to determine if the Kaplan-Baycrest Neurocognitive Assessment (KBNA) was capable of discriminating individuals with subjective memory complaints associated with depression from individuals with mild cognitive impairment (MCI).

Methods:

Scores on 12 subtests of the KBNA were compared for 27 participants with MCI and 28 participants being treated for depression using Bonferroni correct between-group comparisons for each subtest. KBNA subtest scores were corrected for age and education.

Results:

Significant between-group differences were obtained on six subtests with large effect sizes (Cohen's d) ranging from 1.19 - 1.58. The six subtests involved encoding and delayed episodic memory for verbal and visual information. Using logistic regression analysis, five subtests of the KBNA were able to correctly classify 96.4% of study participants.

Conclusion:

The results from this preliminary investigation indicate that the KBNA has the potential to serve as a brief and reliable assessment tool capable of distinguishing individuals with subjective memory complaints associated with depression from individuals with MCI in a clinical setting. Limitations of the current study and future research are discussed.

Type
Original Article
Information
Canadian Journal of Neurological Sciences , Volume 40 , Issue 5 , September 2013 , pp. 670 - 677
Copyright
Copyright © The Canadian Journal of Neurological 2013

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