Hostname: page-component-848d4c4894-pftt2 Total loading time: 0 Render date: 2024-06-01T05:34:26.864Z Has data issue: false hasContentIssue false
  • English
  • Français

Neonatal death due to transposition in association with premature closure of the oval foramen

Published online by Cambridge University Press:  20 November 2006

Michael Ashworth ,
Mudher Al Adnani  and
Neil J. Sebire
Michael Ashworth
Affiliation:
Department of Paediatric Histopathology, Great Ormond Street Hospital, London, United Kingdom
Mudher Al Adnani
Affiliation:
Department of Paediatric Histopathology, Great Ormond Street Hospital, London, United Kingdom
Neil J. Sebire
Affiliation:
Department of Paediatric Histopathology, Great Ormond Street Hospital, London, United Kingdom
Get access Rights & Permissions [Opens in a new window]

Abstract

We present a male infant, born at term, who collapsed and died at 30 minutes of age. Autopsy demonstrated concordant atrioventricular and discordant ventriculo-arterial connections with premature closure of the oval foramen, which bulged markedly into the left atrium. Premature closure of the oval foramen is rare in the setting of transposition. As far as we know, there have been only three previously reported cases.

Keywords

Congenital heart diseasecyanosisneonatal collapse
Type
Brief Report
Information
Cardiology in the Young , Volume 16 , Issue 6 , December 2006 , pp. 586 - 589
Copyright
© 2006 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bhatt DR, Jue KL. Prenatal closure of the foramen ovale in complete transposition of great vessels. Observations in a case with intact ventricular septum and normally developed left heart chambers. Am J Cardiol 1979; 44: 563–565.Google Scholar
Berry LM, Padbury J, Novoa-Takara L. et al. Premature “closing” of the foramen ovale in transposition of the great arteries with intact ventricular septum: rare cause of sudden neonatal death. Pediatr Cardiol 1998; 19: 246–248.Google Scholar
Donofrio MT. Premature closure of the foramen ovale and ductus arteriosus in a fetus with transposition of the great arteries. Circulation 2002; 105: e65.Google Scholar
Lambert EC, Mneon VA, Wagner HR, et al. Sudden unexpected death from cardiovascular disease in children. A cooperative international study. Am J Cardiol 1974; 34: 89–96.Google Scholar